Results 21 to 30 of about 321 (141)
Beilstein Journal of Organic Chemistry, 2023 Peptidomimetics with a substituted imidazo[1,2-a]pyridine fragment were synthesized by a tandem of Groebke–Blackburn–Bienaymé and Ugi reactions. The target products contain substituted imidazo[1,2-a]pyridine and peptidomimetic moieties as pharmacophores ...
Oleksandr V. Kolomiiets +5 more
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A Conserved Isoleucine Gates the Diffusion of CO and O2 to the Active Site of NiFe CO‐Dehydrogenase
Angewandte Chemie, EarlyView.A combination of protein film electrochemistry and site‐directed mutagenesis shows that isoleucine 563 (numbering of Thermococcus sp. AM4) gates the arrival of both CO and O2 to the active site of the nickel‐iron CO dehydrogenases. Mutations at this position increase the resistance to O2 at the cost of a slower reaction with CO.
Laura Opdam +7 more
wiley +2 more sources
(tert-Butyl isocyanide-κC)trichloridogallium(III)
IUCrData, 2016 The crystal structure of (tert-butyl isocyanide-κC)trichloridogallium(III), [GaCl3(C5H9N)], features the first reported isocyanide–gallium trihalide complex. The Ga—C—N—C fragment is essentially linear.
Jeremy L. Bourque +2 more
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The Chemistry of Phenylimidotechnetium(V) Complexes with Isocyanides: Steric and Electronic Factors
Molecules, 2022 Organometallic approaches are of ongoing interest for the development of novel functional 99mTc radiopharmaceuticals, while the basic organotechnetium chemistry seems frequently to be little explored. Thus, structural and reactivity studies with the long-
Guilhem Claude +5 more
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Tris(tert-butyl isocyanide-κC)carbonylnickel(0)
Acta Crystallographica Section E, 2008 The title compound, [Ni(C5H9N)3(CO)], was prepared from Ni(CO)4 and a tenfold excess of tert-butyl isocyanide. It crystallizes with two symmetry-independent molecules per asymmetric unit.
Wolfgang Imhof +2 more
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Isocyanide-Based Multicomponent Reactions for the Synthesis of Heterocycles
Molecules, 2015 Multicomponent reactions (MCRs) are extremely popular owing to their facile execution, high atom-efficiency and the high diversity of products. MCRs can be used to access various heterocycles and highly functionalized scaffolds, and thus have been ...
András Váradi +3 more
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Synthesis and structure of a tetrahedral homoleptic CuI complex with xylyl isocyanide
Acta Crystallographica Section E: Crystallographic CommunicationsTreatment of the CuI precursor [Cu(NCMe)4]PF6 with excess (10 equivalents) of relatively bulky xylyl isocyanide formed a tetra(isocyanide) complex, namely, tetrakis(2,6-dimethylphenylisocyanide)copper(I) hexafluorophosphate, [Cu(C9H9N)4]PF6 or [Cu(CNXyl ...
A. M. Buddhika Chandima +2 more
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Molecules, 2017 A facile access to polysubstituted 3-(isoxazol-5-yl)pyrroles was developed through [3+2] cycloaddition of tosylmethyl isocyanide (TosMIC) and styrylisoxazoles.
Xueming Zhang, Xianxiu Xu, Dawei Zhang
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Molecules, 2023 α-Ketoamide moieties, as privileged units, may represent a valuable option to develop compounds with favorable biological activities, such as low toxicity, promising PK and drug-like properties.
Jia Xu +6 more
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From Isocyanides to Iminonitriles via Silver-mediated Sequential Insertion of C(sp3)–H Bond
iScience, 2019 Summary: Heterocycles are prevalent constituents of many marketing drugs and biologically active molecules to meet modern medical challenges. Isocyanide insertion into C(sp3)–H bonds is challenging especially for the construction of quaternary carbon ...
Huiwen Chi +7 more
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