Results 41 to 50 of about 23,536 (214)

Studies of Isocyanides. I. The Formation of Urethanes and Ureas from Isocyanides [PDF]

Bulletin of the Chemical Society of Japan, 1963
Abstract The reactions of isocyanides with alkyl hypochlorite, N-bromoamides, and hydroxylamine have been investigated. Cyclohexyl and phenyl isocyanides give t-butyl carbamates (urethanes) by the zinc chloride-catalyzed reaction with t-butyl hypochlorite, followed by treatment with water. An analogous reaction with N-bromosuccinimide or
Masaya Okano, Yoshihiko It\={o}, Tatsuya Sh\={o}no, Ryohei Oda   +3 more
openaire   +2 more sources

Crystal structures of methyl 3,5-dibromo-4-cyanobenzoate and methyl 3,5-dibromo-4-isocyanobenzoate

Acta Crystallographica Section E: Crystallographic Communications, 2018
The title crystals, C9H5Br2NO2, are the first reported 2,6-dihalophenyl cyanide–isocyanide pair that have neither three- nor two-dimensional isomorphism. Both crystals contain contacts between the carbonyl O atom and a Br atom.
Wayland E. Noland, Ryan J. Herzig, Abigail J. Engwall, Renee C. Jensen, Kenneth J. Tritch   +4 more
doaj   +1 more source

Isocyanides in the Synthesis of Nitrogen Heterocycles [PDF]

Angewandte Chemie International Edition, 2010
AbstractIsocyanides have long proved themselves to be irreplaceable building blocks in modern organic chemistry. The unique features of the isocyano group make isocyanides particularly useful for the synthesis of a number of important classes of nitrogen heterocycles, such as pyrroles, indoles, and quinolines.
Lygin, Alexander V., de Meijere, Armin
openaire   +5 more sources

High‐Throughput Strategies for Streamlining Lipid Nanoparticle Development Pipeline

Advanced Science, EarlyView.
This review highlights emerging state‐of‐the‐art high‐throughput strategies for optimising lipid nanoparticle formulation. By integrating combinatorial design, characterization, in vitro/in vivo screening, automation, and machine learning into a closed‐loop framework, it provides a roadmap to streamline discovery and accelerate the translation of ...
Lois Lam, Stephanie Watson, Yogambha Ramaswamy, Gurvinder Singh   +3 more
wiley   +1 more source

Isolierung von anionischen N‐heterocyclischen Olefinen und ihre vielseitige Reaktivität

Angewandte Chemie, EarlyView.
Es wird ein neuer Syntheseweg zu anionischen N‐heterocyclischen Olefinen (NHO) durch Ligandenaustausch in metallierten Yliden/Diazomethanen mit freien Carbenen beschrieben. Die anionischen NHOs weisen abgewinkelte Strukturen mit delokalisierter anionischer Ladung auf, was eine vielseitige Reaktivität ermöglicht, einschließlich der Darstellung ...
Prakash Duari, Alexander Linke, Margarita Shishkova, Quentin Le Dé, Arpan Das, Viktoria H. Gessner   +5 more
wiley   +1 more source

Studies on the interaction of isocyanides with imines: reaction scope and mechanistic variations

Beilstein Journal of Organic Chemistry, 2014
The interaction of imines with isocyanides has been studied. The main product results from a sequential process involving the attack of two units of isocyanide, under Lewis acid catalysis, upon the carbon–nitrogen double bond of the imine to form the 4 ...
Ouldouz Ghashghaei, Consiglia Annamaria Manna, Esther Vicente-García, Marc Revés, Rodolfo Lavilla   +4 more
doaj   +1 more source

Isolation of Anionic N‐Heterocyclic Olefins and Their Versatile Reactivity

Angewandte Chemie International Edition, EarlyView.
A new synthetic approach to anionic N‐heterocyclic olefins (NHOs) via ligand exchange of metalated ylides/diazomethanes with free carbenes is reported. The anionic NHOs adopt bent structures with delocalized anionic charge, which enables versatile reactivity, including the formation of highly functionalized NHOs, thermal rearrangement to N‐heterocyclic
Prakash Duari, Alexander Linke, Margarita Shishkova, Quentin Le Dé, Arpan Das, Viktoria H. Gessner   +5 more
wiley   +1 more source

Gold Liquid Crystals in the XXI Century

Inorganics, 2014
Since the first gold liquid crystal was described in 1986, much effort has been done to prepare new compounds bearing this property. The review deals with the last results obtained in this new century.
Manuel Bardají
doaj   +1 more source

Artificial intelligence‐assisted design, synthesis and analysis of smart biomaterials

BMEMat, EarlyView.
Smart biomaterials are rapidly emerging as tools for tissue engineering, and artificial intelligence has played essential roles in biomaterial studies. By bridging the literature gap in AI‐based design, synthesis and analysis of smart biomaterials, the current review shares perspectives on how biomaterial scientists can practically incorporate AI for ...
Pengfei Jiang, Yefei Dai, Yujun Hou, Joshua Stein, Shichen Steven Lin, Chaochen Zhou, Yannan Hou, Rongrong Zhu, Ki‐Bum Lee, Letao Yang   +9 more
wiley   +1 more source

Fungal Isocyanide Synthases and Xanthocillin Biosynthesis in Aspergillus fumigatus

mBio, 2018
Microbial secondary metabolites, including isocyanide moieties, have been extensively mined for their repertoire of bioactive properties. Although the first naturally occurring isocyanide (xanthocillin) was isolated from the fungus Penicillium notatum ...
Fang Yun Lim, Tae Hyung Won, Nicholas Raffa, Joshua A. Baccile, Jen Wisecaver, Antonis Rokas, Frank C. Schroeder, Nancy P. Keller   +7 more
doaj   +1 more source