Results 61 to 70 of about 22,465 (222)

Cyclopropylamine‐Derived Distonic Iminium Radicals: Photoinduced Strategies in Chemo‐ and Stereo‐Selective Synthesis

Chemistry – A European Journal, EarlyView.
Cyclopropylamines have emerged as powerful photocatalytic building blocks. Upon light‐induced single‐electron oxidation, they undergo strain‐release ring opening to generate distonic iminium radicals that enable diverse transformations, including ring‐opening functionalization, formal [3 + 2] cycloadditions, radical cascades, and asymmetric bond ...
Maria Chiara Cabua, Alberto Luridiana, Francesco Secci, Emanuele Cocco   +3 more
wiley   +1 more source

Crystal structures of methyl 3,5-dibromo-4-cyanobenzoate and methyl 3,5-dibromo-4-isocyanobenzoate

Acta Crystallographica Section E: Crystallographic Communications, 2018
The title crystals, C9H5Br2NO2, are the first reported 2,6-dihalophenyl cyanide–isocyanide pair that have neither three- nor two-dimensional isomorphism. Both crystals contain contacts between the carbonyl O atom and a Br atom.
Wayland E. Noland, Ryan J. Herzig, Abigail J. Engwall, Renee C. Jensen, Kenneth J. Tritch   +4 more
doaj   +1 more source

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

Chemistry – A European Journal, EarlyView.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

Tuning π-Acceptor/σ-Donor Ratio of the 2-Isocyanoazulene Ligand: Non-Fluorinated Rival of Pentafluorophenyl Isocyanide and Trifluorovinyl Isocyanide Discovered

Molecules, 2021
Isocyanoazulenes (CNAz) constitute a relatively new class of isocyanoarenes that offers rich structural and electronic diversification of the organic isocyanide ligand platform. This article considers a series of 2-isocyano-1,3-X2-azulene ligands (X = H,
Mason D. Hart, John J. Meyers, Zachary A. Wood, Toshinori Nakakita, Jason C. Applegate, Nathan R. Erickson, Nikolay N. Gerasimchuk, Mikhail V. Barybin   +7 more
doaj   +1 more source

Fluorinated and B‐Vinylated Tris(pyridyl)borate in Copper(I) Coordination Chemistry

European Journal of Inorganic Chemistry, EarlyView.
Coordinatively flexible tris(pyridyl)borate stabilizes copper coordination complexes, including those with ethylene and carbon monoxide. Fluorinated tris(pyridyl)borate with a vinyl substituent on boron was synthesized and comprehensively characterized, expanding the diversity and functional versatility of the poly(pyridyl)borate ligand family.
Deepika V. Karade, Mukundam Vanga, Xiuxiu Sun, H. V. Rasika Dias   +3 more
wiley   +1 more source

Triple-Consecutive Isocyanide Insertions with Aldehydes: Synthesis of 4‑Cyanooxazoles [PDF]

, 2023
An efficient TMSOTf-promoted selective triple consecutive insertions of tert-butyl isocyanide into aldehydes has been developed, affording pharmacological interesting 4-cyanooxazoles in high yields in a one pot manner.
Chang-Hua Ding, Shaohang Lu (14515168), Shaohang Lu, Bin Xu, Chang-Hua Ding (1701772), Bin Xu (10691)   +5 more
core   +1 more source

Rhodium‐Catalyzed Carbene Transfer to Isocyanides Using Zinc Carbenoids

European Journal of Organic Chemistry, EarlyView.
A diazo‐free rhodium‐catalyzed carbene transfer to isocyanides using zinc carbenoids generated from α‐acyloxy halides is reported. This mild protocol furnishes ketenimines that can either be hydrolyzed to amides or intercepted with trimethylsilyl azide or carboxylic acids to give tetrazoles and imides, respectively.
Thomas R. Roose, Guillaume Voegeli, Max C. M. de Vries, Jordy M. Saya, Romano V. A. Orru, Eelco Ruijter   +5 more
wiley   +1 more source

Fungal Isocyanide Synthases and Xanthocillin Biosynthesis in Aspergillus fumigatus

mBio, 2018
Microbial secondary metabolites, including isocyanide moieties, have been extensively mined for their repertoire of bioactive properties. Although the first naturally occurring isocyanide (xanthocillin) was isolated from the fungus Penicillium notatum ...
Fang Yun Lim, Tae Hyung Won, Nicholas Raffa, Joshua A. Baccile, Jen Wisecaver, Antonis Rokas, Frank C. Schroeder, Nancy P. Keller   +7 more
doaj   +1 more source

isocyanides

, 2014
Citation: 'isocyanides' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.I03270 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Retro‐Hetero‐Michael Addition Strategies in Organic Synthesis

European Journal of Organic Chemistry, EarlyView.
In this review, synthetic approaches to carbo‐ and heterocyclic compounds, including natural products, published in the last 15 years (2011–2025) which have either relied upon or included a retro‐hetero‐Michael addition step at any stage are discussed.
Dina Scarpi, Ernesto G. Occhiato
wiley   +1 more source