Results 71 to 80 of about 321 (141)

Multiple Isocyanide insertions promoted by protic and Lewis acids

Tetrahedron Chem
The protonation, or Lewis Acid complexation, of electrophiles can trigger the sequential insertion of two or more isocyanides resulting in valuable iminonitriles or heterocycles.
John Kornfeind, Fraser F. Fleming
doaj   +1 more source

Fluorinated and B‐Vinylated Tris(pyridyl)borate in Copper(I) Coordination Chemistry

European Journal of Inorganic Chemistry, Volume 29, Issue 24, 21 August 2026.
Coordinatively flexible tris(pyridyl)borate stabilizes copper coordination complexes, including those with ethylene and carbon monoxide. Fluorinated tris(pyridyl)borate with a vinyl substituent on boron was synthesized and comprehensively characterized, expanding the diversity and functional versatility of the poly(pyridyl)borate ligand family.
Deepika V. Karade, Mukundam Vanga, Xiuxiu Sun, H. V. Rasika Dias   +3 more
wiley   +1 more source

From o‐Phenylenediamine to Flavin Derivatives: A Potential Prebiotic Carbon Skeleton Expansion With Formaldehyde, Cyanide, and CO2

Advanced Synthesis &Catalysis, Volume 368, Issue 16, 18 August 2026.
A Strecker‐type reaction of aromatic ortho‐diamines with various aldehydes and cyanide assembles the bicyclic amidine core of flavin‐derived heterocycles under mild conditions. Subsequent oxidation, radical or photochemical cyanation, carboxylation with CO2, and CO2‐mediated cyclization build the three‐ring alloxazine scaffold. This sequence provides a
Christian Held, Rodrigo José da Silva Lima, Ji‐Woong Lee   +2 more
wiley   +1 more source

Optical Investigation of 2-amino-7-isocyanofluorene, a Novel Blue-Emitting Solvatochromic Dye

Colorants
Smart solvatochromic isocyano-aminoarenes (ICAArs) have been gaining attention owing to their unique photophysical, antifungal and anticancer properties.
Bence Kontra, Zoltán Mucsi, László Vanyorek, Miklós Nagy   +3 more
doaj   +1 more source

Ugi post-condensation copper-triggered oxidative cascade towards pyrazoles

Beilstein Journal of Organic Chemistry, 2011
Pyrazolidinones were prepared in a two-step sequence starting from α-hydrazonocarboxylic acids. After a four-component Ugi coupling, the resulting hydrazone was engaged in a copper triggered [3 + 2] cycloaddition/aerobic oxidation cascade.
Aurélie Dos Santos, Laurent El Kaim, Laurence Grimaud, Caroline Ronsseray   +3 more
doaj   +1 more source

Novel neutral iron(II) isocyanide maleonitrile dithiolate [Fe(S2C2(CN)2)(t-BuNC) 4] compound

Química Nova, 2004
FeBr2 reacts with the S2C2(CN)2(2-) ion (1:1 ratio) in the presence of an excess of t-BuNC in THF to give the mixed ligand [Fe(S2C2(CN)2)(t-BuNC) 4] compound.
Milton K. Morigaki, Elias M. da Silva, Carlos V. P. de Melo, Carlos Larica, Armando Biondo, Jair C. C. Freitas, Gilson H. M. Dias, Holgadinei R. Ribeiro   +7 more
doaj   +1 more source

A Novel Strategy of Ugi-4CR/Huisgen 1,3-Dipolar Synthesis of 1H-1,2,3-Triazole-Modified Peptidoimetics [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2018
In this protocol, we report a novel approach for the synthesis of a new class of heterocyclic 1H-1,2,3-triazole-modified peptidomimetic compounds. The process consists of an Ugi four-component condensation reaction of amines, an isocyanide, an aldehyde ...
Ahmad Shaabani, Hamid Mofakham, Fatemeh Hajishaabanha, Sajjad Mousavi Faraz, Milad Pedarpour Vajargahy   +4 more
doaj  

Multicomponent synthesis of artificial nucleases and their RNase and DNase activity

Beilstein Journal of Organic Chemistry, 2011
The synthesis of new, artificial ribonucleases containing two amino acid residues connected by an aliphatic linker has been developed. Target molecules were synthesized via a catalytic three-component Ugi reaction from aliphatic diisocyanides ...
Anton V. Gulevich, Lyudmila S. Koroleva, Olga V. Morozova, Valentina N. Bakhvalova, Vladimir N. Silnikov, Valentine G. Nenajdenko   +5 more
doaj   +1 more source

Synthesis of spiroindolenines through a one-pot multistep process mediated by visible light

Beilstein Journal of Organic Chemistry
Spiro-heterocyclic indolenines are privileged scaffolds widely present in numerous indole alkaloids. Here, we develop a novel approach for the one-pot multistep synthesis of different spiro[indole-isoquinolines].
Francesco Gambuti, Jacopo Pizzorno, Chiara Lambruschini, Renata Riva, Lisa Moni   +4 more
doaj   +1 more source

Efficacy of radical reactions of isocyanides with heteroatom radicals in organic synthesis

Beilstein Journal of Organic Chemistry
Isocyanide is a promising synthetic reagent not only as a one-carbon homologation reagent but also as a nitrogen source for nitrogen-containing molecules.
Akiya Ogawa, Yuki Yamamoto
doaj   +1 more source