Results 61 to 70 of about 23,536 (214)

Catalytic Reactions Involving the Oxidative Addition of Si─Halogen and Si─Pseudohalogen Bonds as a Key Step

Chemistry – An Asian Journal, Volume 20, Issue 20, October 17, 2025.
This review highlights the transition metal‐catalyzed reactions in which the oxidative addition of R3Si‐X (I, Br, Cl, F, and OTf) appears to be a key step. The reaction of C─C multiple bonds, such as alkenes, alkynes, and 1,3‐dienes with R3Si‐X proceeds though silylmetalation.
Naoto Chatani
wiley   +1 more source

The reaction of trout hemoglobins with isocyanides [PDF]

European Journal of Biochemistry, 1983
Binding of alkylisocyanides of different bulkiness to the two major components of trout hemolysate is presented. In the case of trout hemoglobin I isocyanide binding is pH‐independent, similar to O2 and CO, and the bulkiness of the ligand is related to the endothermicity of ligand binding to the T quaternary state.
B. Giardina, FALCIONI, Giancarlo, M. Coletta, M. Brunori   +3 more
openaire   +4 more sources

Synthesis of Alpha‐Acyloxy‐(1,2,5‐Oxadiazole‐2‐Oxide) Carboxamides via Passerini Multicomponent Reaction. Evaluation of Nitric Oxide‐Releasing and Anti‐Proliferative Properties

Journal of Heterocyclic Chemistry, Volume 62, Issue 10, Page 1285-1292, October 2025.
The Passerini multicomponent reaction was used to synthesize α‐acyloxy‐(1,2,5‐oxadiazole‐2‐oxide)carboxamides in good to excellent yields (67‐97%) under microwave heating. All compounds were able to release NO in solution, within the concentration range of 0.8–7.4 μM. Antiproliferative activity was investigated against LNCaP, MCF‐7, and SK‐MEL‐28 tumor
Nicolas S. Anjos, Gustavo S. Sant’Ana, João Vitor C. Santos, Caroline Alves, Ana Caroline S. Teodoro, Paulo Vinicius de Sousa, Hugo P. Monteiro, Luiz S. Longo Jr   +7 more
wiley   +1 more source

Two new polytypes of 2,4,6-tribromobenzonitrile

Acta Crystallographica Section E: Crystallographic Communications, 2016
Three polymorphs of 2,4,6-tribromobenzonitrile (RCN), C7H2Br3N, two of which are novel and one of which is a redetermination of the original structure first determined by Carter & Britton [(1972). Acta Cryst. B28, 945–950] are found to be polytypic. Each
Doyle Britton, Wayland E. Noland, Kenneth J. Tritch   +2 more
doaj   +1 more source

Combined Inductive and Dispersion Effects Enhance Bioorthogonal Reactivity of Tetrazines Toward Isonitriles

Angewandte Chemie International Edition, Volume 64, Issue 39, September 22, 2025.
Bulky, electron‐withdrawing substituents can significantly enhance the reactivity and stability of tetrazines toward isonitriles, addressing a key challenge in bioorthogonal chemistry. This study explores the role of frontier‐orbital interactions, dispersion forces, and molecular conformation in optimizing tetrazine performance, leading to highly ...
Suprakash Biswas, Andreas Löffler, Pushkar Bansal, Randall T. Peterson, Dennis Svatunek, Raphael M. Franzini   +5 more
wiley   +1 more source

Diversity Oriented Syntheses of Conventional Heterocycles by Smart Multi Component Reactions (MCRs) of the Last Decade

Molecules, 2012
A collection of smart multicomponent reactions (MCRs) with continuative post condensation cyclizations (PCCs) is presented to construct conventional three- to seven-membered heterocyclic compounds in diversity oriented syntheses (DOS). These will provide
Heiner Eckert
doaj   +1 more source

Small Molecule Activation by Metallylenes and their Follow‐Up Reactions

ChemistryEurope, Volume 3, Issue 5, September 18, 2025.
Metallylenes offer a promising, tunable platform for small molecule activation, combining transition metal‐like reactivity with earth abundance. Ligand modifications and computational insights have unlocked new catalytic pathways, expanding their potential in sustainable synthesis.
Eveline H. Tiekink, Matthijs W. Kragtwijk, Trevor A. Hamlin   +2 more
wiley   +1 more source

A New Method for the Synthesis of 1-(1-Isocyanoethyl)adamantane

Molbank
A novel single-step method has been developed for the synthesis of 1-(1-isocyanoethyl)adamantane from 1-(1-adamantylethyl)amine, chloroform, and t-BuOK, in a dichloromethane/tert-butanol (1:1) medium, yielding 92%, which is 27% higher compared to the ...
Dmitry Pitushkin, Gennady Butov
doaj   +1 more source

Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy

Aggregate, Volume 6, Issue 9, September 2025.
Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang, Hao Fu, Jiangtao Lin, Meng Zhao, Chuanrong Chen, Hongze Liao, Yourong Duan   +6 more
wiley   +1 more source

Enlarged‐TriQuinoline (Enl‐TQ): Disparity in Chemical Behaviors by Geometric Scaling of the Trimeric Quinoline Ring System

Chemistry – An Asian Journal, Volume 20, Issue 17, September 4, 2025.
TriQuinoline (TQ), a quasi‐planar cyclic quinoline trimer in a head‐to‐tail arrangement, strongly captures a proton and exhibits unusual physicochemical properties. In this study, we designed and synthesized its expanded analog, Enlarged‐TriQuinoline (Enl‐TQ), in which three alkyne units are embedded between three quinoline units to acquire an expanded
Mai Yamashita, Ryosuke Tsutsumi, Toi Kobayashi, Naoya Kumagai   +3 more
wiley   +1 more source