Isoginkgetin-loaded reactive oxygen species scavenging nanoparticles ameliorate intervertebral disc degeneration via enhancing autophagy in nucleus pulposus cells [PDF]
Excessive reactive oxygen species (ROS) in nucleus pulposus cells (NPCs) promote extracellular matrix (ECM) degradation and cellular inflammatory responses by activating a variety of cellular pathways, ultimately inducing cell apoptosis and leading to ...
Hao Yu +11 more
doaj +2 more sources
First study on in vitro antiviral and virucidal effects of flavonoids against feline infectious peritonitis virus at the early stage of infection [PDF]
Background and Aim: Feline infectious peritonitis (FIP), one of the most important infectious diseases in cats is caused by FIP virus (FIPV), a mutated variant of feline coronavirus.
Chanittha Triratapiban +5 more
doaj +2 more sources
Obesity-induced metabolic cardiomyopathy (MC), characterized by lipotoxicity and excessive oxidative stress, emerges as the leading cause of heart failure in the obese patients. Yet, its therapy remains very limited.
Xiaoqian Wu +9 more
doaj +2 more sources
Patterns of Biflavonoid Accumulation in Ginkgo (Ginkgo biloba L.) Leaves from 90 Trees and Their Variation with Age, Gender, and Location [PDF]
Biflavonoids are dimeric flavonoids recognized for their diverse biological activities and significant pharmacological potential, with ginkgo (Ginkgo biloba L.) serving as a primary natural source.
Dunja Šamec +3 more
doaj +2 more sources
High-performance liquid chromatography – diode array detection method validation for amentoflavone-type biflavonoids in five Encephalartos species with potential neuroprotective activity [PDF]
Ginkgo biloba is a well-known food supplement for enhancing memory and is rich in biflavonoids. Biflavonoids are predominant in the Order Cycadales (cycads). Among cycads, five Encephalartos species, E. ferox, E. kisambo, E. laurentianus, E.
Zainab G. El-Natory +4 more
doaj +2 more sources
Anticancer Effects of Five Biflavonoids from Ginkgo Biloba L. Male Flowers In Vitro
Ginkgo biloba L., an ancient dioecious gymnosperm, is now cultivated worldwide for landscaping and medical purposes. A novel biflavonoid—amentoflavone 7′′-O-β-d-glucopyranoside (1)—and four known biflavonoids were isolated ...
Min Li +7 more
doaj +2 more sources
Drying herbs is a crucial method for stabilizing and preserving their essential properties and bioactive compounds. Although freeze drying is the preferred method for most herbs, it is expensive due to high energy consumption and operating costs ...
Iva Jurčević Šangut +2 more
doaj +2 more sources
Isoginkgetin and Madrasin are poor splicing inhibitors [PDF]
The production of eukaryotic mRNAs requires transcription by RNA polymerase (pol) II and co-transcriptional processing, including capping, splicing, and cleavage and polyadenylation.
Tellier M, Ansa G, Murphy S.
europepmc +8 more sources
Human Telomerase RNA Processing and Quality Control [PDF]
The non-coding RNA subunit of telomerase provides the template for telomerase activity. In diverse fungi, 3′ end processing of telomerase RNA involves a single cleavage by the spliceosome.
Chi-Kang Tseng +5 more
doaj +2 more sources
Seasonal Variation of Polyphenols and Pigments in Ginkgo (Ginkgo biloba L.) Leaves: Focus on 3′,8″-Biflavones [PDF]
Ginkgo (Ginkgo biloba L.) is a widely recognized medicinal plant, often grown as an ornamental species in parks around the world. Its leaves change color from green in spring to yellow in autumn.
Iva Jurčević Šangut, Dunja Šamec
doaj +2 more sources

