The individual components of commercial isometamidium do not possess stronger trypanocidal activity than the mixture, nor bypass isometamidium resistance [PDF]
International Journal for Parasitology: Drugs and Drug Resistance, 2019 The four components present in the trypanocidal treatment Samorin, the commercially available formulation of isometamidium, were separated and purified by column chromatography.
Anthonius A. Eze +4 more
doaj +3 more sources
Genomic analysis of Isometamidium Chloride resistance in Trypanosoma congolense [PDF]
International Journal for Parasitology: Drugs and Drug Resistance, 2017 Isometamidium Chloride (ISM) is one of the principal drugs used to counteract Trypanosoma congolense infection in livestock, both as a prophylactic as well as a curative treatment. However, numerous cases of ISM resistance have been reported in different
Eliane Tihon +5 more
doaj +4 more sources
Trypanosoma evansi and Surra: A review and perspectives on transmission, epidemiology and control, impact, and zoonotic aspects [PDF]
BioMed Research International, Volume 2013, Issue 1, 2013., 2013 This paper reviews the transmission modes of Trypanosoma evansi. Its worldwide distribution is attributed to mechanical transmission. While the role of tabanids is clear, we raise questions on the relative role of Haematobia sp.
Dargantes, Alan +5 more
core +4 more sources
Action trypanocide de deux sels d'isométamidium [PDF]
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1963 cf. fichier PDF de l'article.
Pierre Finelle, R. Lacotte
doaj +3 more sources
Trypanocide Use and Molecular Characterization of Trypanosomes Resistant to Diminazene Aceturate in Cattle in Northern Côte D’Ivoire [PDF]
Tropical Medicine and Infectious DiseaseThe resistance of trypanosomes to the doses of trypanocide administered by farmers to their animals acts as a real brake on efforts to control to combat African trypanosomiasis.
Jean-Yves Ekra +6 more
doaj +2 more sources
Prothidium and isometamidium as drug against Trypanosoma brucei canine trypanosomiasis
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1970 Le Prothidium et l'Isométamidium ont été utilisés dans le traitement de plusieurs cas de trypanosomiase expérimentale du chien à Trypanosoma brucei. Le Prothidium est administré à raison de 2 mg/kg de la solution à 2 p.100 et l'Isométamidium 1 mg/kg de ...
Saydil Touré
doaj +3 more sources
Chemosensitization of Trypanosoma congolense strains resistant to isometamidium chloride by tetracyclines and enrofloxacin. [PDF]
PLoS Neglected Tropical Diseases, 2010 BACKGROUND: Because of the development of resistance in trypanosomes to trypanocidal drugs, the livelihood of millions of livestock keepers in sub-Saharan Africa is threatened now more than ever.
Vincent Delespaux +7 more
doaj +7 more sources
Longitudinal observational (single cohort) study on the causes of trypanocide failure in cases of African animal trypanosomosis in cattle near wildlife protected areas of Northern Tanzania. [PDF]
PLoS Neglected Tropical DiseasesAfrican animal trypanosomosis (AAT) in cattle is primarily managed through trypanocide administration and insecticide application. Trypanocides can be used for both treatment and prophylaxis, but failure is often reported; this may occur due to ...
Shauna Richards +13 more
doaj +2 more sources
Assessment of Veterinary Drug Availability, Storage Conditions, and Handling Practices in and Around Nekemte Town, Southwestern Oromia, Ethiopia. [PDF]
Vet Med IntAnimal diseases pose a significant threat to both animal welfare and productivity, making veterinary drugs essential for their prevention, treatment, and control. In developing countries including Ethiopia, several challenges such as limited drug availability, inadequate storage facilities, improper handling, and insufficient knowledge among veterinary
Mekonen AW +4 more
europepmc +2 more sources
Prevalence and Associated Risk Factors of African Animal Trypanosomiasis in Cattle in Lambwe, Kenya. [PDF]
J Parasitol Res, 2022 Background. African animal trypanosomiasis (AAT) affects livestock productivity in sub‐Saharan Africa. This study aimed to determine cattle AAT’s prevalence and associated risk factors in Lambwe Valley, Kenya. Methods. In a cross‐sectional survey, livestock owners were recruited from four villages of Lambwe in Homa Bay, Kenya.
Okello I +5 more
europepmc +2 more sources