Results 21 to 30 of about 475 (151)

Investigation on Prevalence of Canine Trypanosomiasis in the Conservation Areas of Bwindi‐Mgahinga and Queen Elizabeth in Western Uganda

Journal of Parasitology Research, Volume 2022, Issue 1, 2022., 2022
Nowadays, despite the instauration of several control strategies, animal trypanosomiasis continues to be reported all over Uganda. Few canine African trypanosomiasis (CAT) studies have been carried out, yet dogs are known Trypanosoma reservoirs that share identical home ranges with livestock and serve as parasite link between livestock and humans. This
James Robert Ochieng, Marta Planellas Bachs, Anthony Nsubuga, Innocent B. Rwego, John Joseph M. Kisakye, Laura Muro Riba, Jesus Muro Figueres, John Kagira   +7 more
wiley   +1 more source

Knowledge, Attitude, and Practice of Livestock Owners and Livestock Assistants towards African Trypanosomiasis Control in The Gambia

Journal of Parasitology Research, Volume 2022, Issue 1, 2022., 2022
Background. In Africa, it has been estimated that 50 million cattle and 70 million sheep and goats are at risk of animal African trypanosomiasis, and three million cattle die annually. Methods. This study was conducted in all the regions of The Gambia except Kombo Saint Mary Island (Banjul).
Alpha Kargbo, Edrisa Jawo, Amien Isaac Amoutchi, Herve Koua, Rex Kuye, Zainabou Dabre, Abdoulie Bojang, Rafael F. C. Vieira, Lizandra Guidi Magalhães   +8 more
wiley   +1 more source

Diminazene resistance in Trypanosoma congolense is not caused by reduced transport capacity but associated with reduced mitochondrial membrane potential

Molecular Microbiology, Volume 116, Issue 2, Page 564-588, August 2021., 2021
Resistance to diminazene is one of the main problems facing the control of the livestock disease Animal African Trypanosomiasis (AAT, or nagana), caused by the parasite Trypanosoma congolense. We investigated the adaptations of the parasite that allow it to resist the drug and find that changes to the mitochondrion, where the parasite produces its ...
Lauren V. Carruthers, Jane C. Munday, Godwin U. Ebiloma, Pieter Steketee, Siddharth Jayaraman, Gustavo D. Campagnaro, Marzuq A. Ungogo, Leandro Lemgruber, Anne‐Marie Donachie, Tim G. Rowan, Rose Peter, Liam J. Morrison, Michael P. Barrett, Harry P. De Koning   +13 more
wiley   +1 more source

Molecular Identification of ABC2 Transporter Gene Encode Protein Ngawi Trypanosoma evansi Isolate that suspected resistance to Isometamidium Chloride [PDF]

BIO Web of Conferences, 2021
This study aims to determine the profile of the ABC2 encoding transporter on Trypanosoma evansi (T. evansi) Ngawi isolates, Indonesia, exposed with Isometamidium Chloride (ISM). This study used blood samples of mice containing Trypanosoma evansi that had
Wusahaningtyas Lu’lu’ Sahara, Nuryady Moh Mirza, Firdausy Lintang Winantya, Fahrurrozi Zs Ahmad, Nurcahyo R. Wisnu   +4 more
doaj   +1 more source

Prevalence of Bovine Trypanosomosis and Its Associated Risk Factor in Hawa Galan District, Kelem Wollega Zone of Ethiopia

Veterinary Medicine International, Volume 2021, Issue 1, 2021., 2021
An analytical cross‐sectional study was performed between November 2015 and April 2016 at Hawa Galan woreda, Kelem Wollega Zone, Oromia Region, Ethiopia, to estimate the proportion of cattle with trypanosomosis and to evaluate the elements associated with the prevalence of bovine trypanosomosis.
Girma Tsegaye, Belay Abebe, Geremew Haile, Remo Lobetti   +3 more
wiley   +1 more source

Antiprotozoal Drug Handling and Management Practices in Asella District, Central Oromia, Ethiopia

Veterinary Medicine International, Volume 2021, Issue 1, 2021., 2021
Background and Methods. Protozoal infections such as dourine caused by trypanosomes are found to be a threat to the life and productivity of the equine population. Inappropriate drug use is a problem of the whole world; however, the degree of the problem is higher in developing countries like Ethiopia.
Ashenafi Ababu, Dereje Endashaw, Haben Fesseha, Mesfin Mathewos, Carlos Alberto Hussni   +4 more
wiley   +1 more source

Reduced Mitochondrial Membrane Potential Is a Late Adaptation of Trypanosoma brucei brucei to Isometamidium Preceded by Mutations in the γ Subunit of the F1Fo-ATPase.

PLoS Neglected Tropical Diseases, 2016
BackgroundIsometamidium is the main prophylactic drug used to prevent the infection of livestock with trypanosomes that cause Animal African Trypanosomiasis.
Anthonius A Eze, Matthew K Gould, Jane C Munday, Daniel N A Tagoe, Valters Stelmanis, Achim Schnaufer, Harry P De Koning   +6 more
doaj   +1 more source

Effect of isometamidium hydrochloride on Trypanosoma evansi infections in rats [PDF]

Journal of Parasitic Diseases, 2009
Effect of Isometamidium treatment of rats infected with Trypanosoma evansi was studied under experimental condition. The infection resulted in 100 per cent mortality by 7 day post treatment (DPT) in the infected untreated rats (Gr.II) and Isometamidium-HCl exerted 90 percent anti-trypanosomal efficacy.
Upendra, Kumar, Ruma, Jas, J D, Ghosh
openaire   +2 more sources

Study of plasma protein binding activity of isometamidium and its impact on anthelmintic activity using trypanosoma induced calf model

Veterinary World, 2013
Aim: The objective of present study was to determine Plasma Protein Binding (PPB) activity and its effect on clinical efficacy of isometamidium after intramuscular administration in calves.
Suprita Sinha, Shweta Anand, Tapan Kumar Mandal   +2 more
doaj   +1 more source

Evaluation of isometamidium levels in the serum of sheep and goats after prophylactic treatment against trypanosomosis

Onderstepoort Journal of Veterinary Research, 2004
years, but recently there have been reports of prophylaxis failure under natural conditions. In this study, use of the drug for prophylactic purpose against trypanosomosis in small ruminants was investigated.
J.O. Wesongah, G.A. Murilla, J.K. Kibugu, T.W. Jones   +3 more
doaj   +1 more source