Results 31 to 40 of about 475 (151)
An overview is presented of the results obtained with biodegradable sustained release devices (SRDs) containing a mixture of polymers and either isometamidium (ISMM) or ethidium. Under controlled laboratory conditions (monthly challenge with tsetse flies
S Geerts, JRA Brandt, R De Deken
doaj +1 more source
Based on a survey in a few villages of the department of Faro et Deo, the village of Kontcha, where the highest trypanosomosis prevalence (32.5%) was observed, was selected to evaluate the resistance of trypanosomes to diminazene and isometamidium.
A. Mamoudou +8 more
doaj +1 more source
The occurrence of cross-resistance among melarsoprol-resistant Trypanosoma brucei rhodesiense isolates was investigated in this study. The isolates, T. b. rhodesiense KETRI 237, 2538, 1992, 2709, 2694 and 3530, had been obtained from sleeping sickness
N. Maina, J.M. Kagira
doaj +1 more source
Fluorescence analysis of the interaction of isometamidium with Trypanosoma congolense [PDF]
Isometamidium chloride (Samorin) is the only compound recommended for prophylaxis against bovine trypanosomiasis in sub-Saharan Africa. The fluorescence property of this compound was used to investigate the interaction of the molecule with in vitro-derived bloodstream forms of Trypanosoma congolense IL 1180.
Zilberstein, D. +3 more
openaire +2 more sources
Drug Resistant Trypanosomes: a Threat to Cattle Production in the Southwest of Ethiopia
Trypanosomosis is an important disease of cattle in the southwest of Ethiopia. At present chemotherapy and chemoprophylaxis are the only practical methods available for the control of animal trypanosomosis, but their effectiveness is being eroded by the ...
H. Chaka, G. Abébé
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Resistance to trypanocidal drugs has been detected in various African countries and is a serious impediment to the control of livestock trypanosomosis.
S. Jamal +6 more
doaj +1 more source
Trypanosoma congolense is a protozoan parasite that is transmitted by tsetse flies, causing African Animal Trypanosomiasis, also known as Nagana, in sub-Saharan Africa. Nagana is a fatal disease of livestock that causes severe economic losses.
M. Gysin +5 more
doaj +1 more source
Trypanosoma vivax infections cause nonspecific clinical signs in cattle associated with aparasitemic intervals, making disease diagnosis a challenge.
Kayo José Garcia de Almeida Castilho Neto +7 more
doaj +1 more source
The protective efficacy of isometamidium chloride (ISMM) and diminazene aceturate (DIM) against Trypanosoma brucei, Trypanosoma congolense and Trypanosoma vivax infections in cattle under a suppressed tsetse population was assessed in southeast Uganda.
J.W. Magona +3 more
doaj +1 more source
Aberrant use and poor quality of trypanocides: a risk for drug resistance in south western Ethiopia
Background Trypanocidal drugs have been used to control African animal trypanosomosis for several decades. In Ethiopia, these drugs are available from both authorized (legal) and unauthorized (illegal) sources but documentation on utilization practices ...
T. Tekle +14 more
doaj +1 more source

