Results 31 to 40 of about 1,450 (197)
Independence from kinetoplast DNA maintenance and expression is associated with multi-drug resistance in Trypanosoma brucei in vitro [PDF]
, 2014 It is well known that several antitrypanosomatid drugs accumulate in the parasite's mitochondrion, where they often bind to the organellar DNA, the kinetoplast.
A. Schnaufer +32 more
core +1 more source
Veterinary World, 2013 Aim: The objective of present study was to determine Plasma Protein Binding (PPB) activity and its effect on clinical efficacy of isometamidium after intramuscular administration in calves.
Suprita Sinha +2 more
doaj +1 more source
Onderstepoort Journal of Veterinary Research, 2004 years, but recently there have been reports of prophylaxis failure under natural conditions. In this study, use of the drug for prophylactic purpose against trypanosomosis in small ruminants was investigated.
J.O. Wesongah +3 more
doaj +1 more source
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2006 Based on a survey in a few villages of the department of Faro et Deo, the village of Kontcha, where the highest trypanosomosis prevalence (32.5%) was observed, was selected to evaluate the resistance of trypanosomes to diminazene and isometamidium.
A. Mamoudou +8 more
doaj +1 more source
Memorias do Instituto Oswaldo Cruz, 1999 An overview is presented of the results obtained with biodegradable sustained release devices (SRDs) containing a mixture of polymers and either isometamidium (ISMM) or ethidium. Under controlled laboratory conditions (monthly challenge with tsetse flies
S Geerts, JRA Brandt, R De Deken
doaj +1 more source
Onderstepoort Journal of Veterinary Research, 2007 The occurrence of cross-resistance among melarsoprol-resistant Trypanosoma brucei rhodesiense isolates was investigated in this study. The isolates, T. b. rhodesiense KETRI 237, 2538, 1992, 2709, 2694 and 3530, had been obtained from sleeping sickness
N. Maina, J.M. Kagira
doaj +1 more source
Epidemiological study of canine trypanosomosis in an urban area of Ivory Coast [PDF]
, 2009 Following confirmed cases of trypanosomosis in military working dogs, c cross-sectional study was undertaken to evaluate the source of infection and determine the prevalence of canine infection with Trypanosoma congolense in the urban focus of Abidjan ...
Cuny, Gérard +6 more
core +1 more source
Fluorescence analysis of the interaction of isometamidium with Trypanosoma congolense [PDF]
Biochemical Journal, 1993 Isometamidium chloride (Samorin) is the only compound recommended for prophylaxis against bovine trypanosomiasis in sub-Saharan Africa. The fluorescence property of this compound was used to investigate the interaction of the molecule with in vitro-derived bloodstream forms of Trypanosoma congolense IL 1180.
Zilberstein, D. +3 more
openaire +2 more sources
Drug Resistant Trypanosomes: a Threat to Cattle Production in the Southwest of Ethiopia
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2003 Trypanosomosis is an important disease of cattle in the southwest of Ethiopia. At present chemotherapy and chemoprophylaxis are the only practical methods available for the control of animal trypanosomosis, but their effectiveness is being eroded by the ...
H. Chaka, G. Abébé
doaj +1 more source
Integrated cost-benefit analysis of tsetse control and herd productivity to inform control programs for animal African trypanosomiasis [PDF]
, 2018 Animal African trypanosomiasis (AAT) and its tsetse vector are responsible for annual losses estimated in billions of US dollars ($). Recent years have seen the implementation of a series of multinational interventions.
Chilongo, K +7 more
core +1 more source