Results 31 to 40 of about 475 (151)

Laboratory and Field Evaluation of Biodegradable Polyesters for Sustained Release of Isometamidium and Ethidium

open access: yesMemorias do Instituto Oswaldo Cruz, 1999
An overview is presented of the results obtained with biodegradable sustained release devices (SRDs) containing a mixture of polymers and either isometamidium (ISMM) or ethidium. Under controlled laboratory conditions (monthly challenge with tsetse flies
S Geerts, JRA Brandt, R De Deken
doaj   +1 more source

Assessment of the Resistance of Cattle Trypanosomes to Diminazene Aceturate and Isometamidium Chloride on the Adamawa Plateau in Cameroon Using a Field Test and a Test in Mice

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2006
Based on a survey in a few villages of the department of Faro et Deo, the village of Kontcha, where the highest trypanosomosis prevalence (32.5%) was observed, was selected to evaluate the resistance of trypanosomes to diminazene and isometamidium.
A. Mamoudou   +8 more
doaj   +1 more source

Occurrence of multiple drug resistance in Trypanosoma brucei rhodesiense isolated from sleeping sickness patients

open access: yesOnderstepoort Journal of Veterinary Research, 2007
The occurrence of cross-resistance among melarsoprol-resistant Trypanosoma brucei rhodesiense isolates was investigated in this study. The isolates, T. b. rhodesiense KETRI 237, 2538, 1992, 2709, 2694 and 3530, had been obtained from sleeping sickness
N. Maina, J.M. Kagira
doaj   +1 more source

Fluorescence analysis of the interaction of isometamidium with Trypanosoma congolense [PDF]

open access: yesBiochemical Journal, 1993
Isometamidium chloride (Samorin) is the only compound recommended for prophylaxis against bovine trypanosomiasis in sub-Saharan Africa. The fluorescence property of this compound was used to investigate the interaction of the molecule with in vitro-derived bloodstream forms of Trypanosoma congolense IL 1180.
Zilberstein, D.   +3 more
openaire   +2 more sources

Drug Resistant Trypanosomes: a Threat to Cattle Production in the Southwest of Ethiopia

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2003
Trypanosomosis is an important disease of cattle in the southwest of Ethiopia. At present chemotherapy and chemoprophylaxis are the only practical methods available for the control of animal trypanosomosis, but their effectiveness is being eroded by the ...
H. Chaka, G. Abébé
doaj   +1 more source

The susceptibility of Trypanosoma congolense isolated in Zambézia Province, Mozambique, to isometamidium chloride, diminazene aceturate and homidium chloride

open access: yesOnderstepoort Journal of Veterinary Research, 2005
Resistance to trypanocidal drugs has been detected in various African countries and is a serious impediment to the control of livestock trypanosomosis.
S. Jamal   +6 more
doaj   +1 more source

Isothermal microcalorimetry – A quantitative method to monitor Trypanosoma congolense growth and growth inhibition by trypanocidal drugs in real time

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2018
Trypanosoma congolense is a protozoan parasite that is transmitted by tsetse flies, causing African Animal Trypanosomiasis, also known as Nagana, in sub-Saharan Africa. Nagana is a fatal disease of livestock that causes severe economic losses.
M. Gysin   +5 more
doaj   +1 more source

Follow-up of dairy cattle naturally infected by Trypanosoma vivax after treatment with isometamidium chloride

open access: yesRevista Brasileira de Parasitologia Veterinária, 2021
Trypanosoma vivax infections cause nonspecific clinical signs in cattle associated with aparasitemic intervals, making disease diagnosis a challenge.
Kayo José Garcia de Almeida Castilho Neto   +7 more
doaj   +1 more source

Protective efficacy of isometamidium chloride and diminazene aceturate against natural Trypanosoma brucei, Trypanosoma congolense and Trypanosoma vivax infections in cattle under a suppressed tsetse population in Uganda

open access: yesOnderstepoort Journal of Veterinary Research, 2004
The protective efficacy of isometamidium chloride (ISMM) and diminazene aceturate (DIM) against Trypanosoma brucei, Trypanosoma congolense and Trypanosoma vivax infections in cattle under a suppressed tsetse population was assessed in southeast Uganda.
J.W. Magona   +3 more
doaj   +1 more source

Aberrant use and poor quality of trypanocides: a risk for drug resistance in south western Ethiopia

open access: yesBMC Veterinary Research, 2018
Background Trypanocidal drugs have been used to control African animal trypanosomosis for several decades. In Ethiopia, these drugs are available from both authorized (legal) and unauthorized (illegal) sources but documentation on utilization practices ...
T. Tekle   +14 more
doaj   +1 more source

Home - About - Disclaimer - Privacy