Results 51 to 60 of about 475 (151)

Spatiotemporal changes in prevalence of Sodalis glossinidius, Spiroplasma spp. and trypanosome species in wild Glossina tachinoides from Sora‐Mboum animal African trypanosomiasis focus in northern Cameroon

Insect Science, Volume 32, Issue 5, Page 1713-1725, October 2025.
Abstract Sterile Insect Technique (SIT) has proven effective to reduce tsetse population density in large infected areas where animal African trypanosomosis (AAT) and human African trypanosomiasis (HAT) elimination was difficult to achieve. However, the decrease in mass production of insectary‐reared tsetse and the limited but incomplete knowledge on ...
Steve Feudjio Soffack, Tito T. Melachio Tanekou, Hugues C. Nana Djeunga, Oumarou Farikou, Ginette I. Kame Ngasse, Mureille C. Tchami Mbagnia, Murielle Wondji, Charles S. Wondji, Hager Khalil, Adly M. M. Abd‐Alla, Anne Geiger, Gustave Simo, Flobert Njiokou   +12 more
wiley   +1 more source

Trypanosoma evansi and Surra: A Review and Perspectives on Transmission, Epidemiology and Control, Impact, and Zoonotic Aspects

BioMed Research International, Volume 2013, Issue 1, 2013., 2013
This paper reviews the transmission modes of Trypanosoma evansi. Its worldwide distribution is attributed to mechanical transmission. While the role of tabanids is clear, we raise questions on the relative role of Haematobia sp. and the possible role of Stomoxys sp. in delayed transmission.
Marc Desquesnes, Alan Dargantes, De-Hua Lai, Zhao-Rong Lun, Philippe Holzmuller, Sathaporn Jittapalapong, Jude M. Przyborski   +6 more
wiley   +1 more source

Evaluation of trypanocidal and anthelmintic efficacy of an Isometamidium – Ivermectin association in bovine

Revista Científica, 2021
The objective of the present work was to evaluate the efficacy of the compound Hemoveex® (isometamidium chloride  2,4% and ivermectin 2,0%) of  Reveex,  a  Venezuelan  laboratory, on the control of mixed infections of Trypanosoma vivax and ...
Gustavo López-Valencia, Jesús Antonio Betancourt-Echeverry, Elias Ascanio-Evanoff, Willia Berrío-Cataño, Andrés Felipe Velásquez-Arboleda, Jorge Gómez-Oquendo, Gustavo Alonso López-Sierra   +6 more
doaj  

Investigation of Novel Isatinylhydantoin Derivatives as Potential Anti‐Kinetoplastid Agents

ChemMedChem, Volume 20, Issue 1, January 2, 2025.
A series of isatinylhydantoin derivatives were synthesized and investigated for antileishmanial and antitrypanosomal activities in vitro and in vivo. The derivative 5 was identified with higher leishmanicidal activity than the clinical drug amphotericin B while 4b was uncovered as in vitro trypanocidal hit against T. congolense parasite.
Keamogetswe Sechoaro, Janine Aucamp, Christina Kannigadu, Helena D. Janse van Rensburg, Keisuke Suganuma, David D. N'Da   +5 more
wiley   +1 more source

Immunological and Therapeutic Strategies against Salmonid Cryptobiosis

BioMed Research International, Volume 2010, Issue 1, 2010., 2010
Salmonid cryptobiosis is caused by the haemoflagellate, Cryptobia salmositica. Clinical signs of the disease in salmon (Oncorhynchus spp.) include exophthalmia, general oedema, abdominal distension with ascites, anaemia, and anorexia. The disease‐causing factor is a metalloprotease and the monoclonal antibody (mAb‐001) against it is therapeutic.
Patrick T. K. Woo, Luis I. Terrazas
wiley   +1 more source

Immunobiology of African Trypanosomes: Need of Alternative Interventions

BioMed Research International, Volume 2010, Issue 1, 2010., 2010
Trypanosomiasis is one of the major parasitic diseases for which control is still far from reality. The vaccination approaches by using dominant surface proteins have not been successful, mainly due to antigenic variation of the parasite surface coat.
Toya Nath Baral, Jorge Morales-Montor
wiley   +1 more source

Monitoring the incidence of trypanosomosis in cattle during the release of sterilized tsetse flies on Unguja Island, Zanzibar

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2000
The incidence of trypanosomosis in sentinel cattle on Unguja Island, Zanzibar, was monitored every two to five months in 1994-97 to observe changes in disease transmission attributable logically to the application of insecticides, the release of ...
V. A. Dyck, H. Pan, S. S. Kassim, F. W. Suleiman, W. A. Mussa, K. M. Saleh, K. G. Juma, P. A. Mkonyi, W. G. Holland, B. J.M. Van Der Eerden, R. H. Dwinger   +10 more
doaj   +1 more source

Kinetic modelling of isometamidium chloride (Samorin) uptake byTrypanosoma congolense

Parasitology, 1992
Clones ofTrypanosoma congolensewhich express resistance to the widely used trypanocide isometamidium chloride accumulate less of the drug than clones which are sensitive to drug treatment. A mathematical model has been developed which was able to predict theoretical lines representing the uptake kinetics in trypanosomes which were sensitive to ...
Sutherland, IA, Mounsey, A, Eisler, MC, Holmes, PH   +3 more
openaire   +3 more sources

Tractable Quinolone Hydrazides Exhibiting Sub‐Micromolar and Broad Spectrum Antitrypanosomal Activities

ChemMedChem, Volume 19, Issue 9, May 2, 2024.
Several (sub)species of Trypanosoma are responsible for human African trypanosomiasis (HAT), Chagas disease, and Nagana. These (sub)species have different drug susceptibility profiles. This work reports several easily accessed quinolone hydrazides exhibiting sub‐micromolar activities against multiple (sub)species of Trypanosoma.
Kgothatso A. Chirwa, Karol R. Francisco, Phelelisiwe S. Dube, Hayoung Park, Lesetja J. Legoabe, Thaiz Rodrigues Teixeira, Conor R. Caffrey, Richard M. Beteck   +7 more
wiley   +1 more source

Isometamidium chloride and homidium chloride fail to cure mice infected with Ethiopian Trypanosoma evansi type A and B. [PDF]

PLoS Neglected Tropical Diseases, 2018
BACKGROUND:Trypanosoma evansi is mechanically transmitted by biting flies and affects camels, equines, and other domestic and wild animals in which it causes a disease called surra.
Gebrekrustos Mekonnen, Elmi Fahiye Mohammed, Weldu Kidane, Awol Nesibu, Hagos Yohannes, Nick Van Reet, Philippe Büscher, Hadush Birhanu   +7 more
doaj   +1 more source