Results 51 to 60 of about 1,529 (123)

Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024

FEBS Open Bio, Volume 15, Issue 11, Page 1726-1737, November 2025.
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior, Michaela Kocholata, Marilena E. Lekka, Olga Janouskova, Moran Yadid, Maja Kosanovic   +5 more
wiley   +1 more source

A Survey Of MicroRNA Length Variants Contributing To MiRNome Complexity In Peach (Prunus persica)

Frontiers in Plant Science, 2012
MicroRNAs (miRNAs) are short non coding RNA molecules produced from hairpin structures and involved in gene expression regulation with major roles in plant development and stress response.
Moreno eColaiacovo, Letizia eBernardo, Isabella eCentomani, Cristina eCrosatti, Lorenzo eGiusti, Luigi eOrrù, Gianni eTacconi, Antonella eLamontanara, Luigi eCattivelli, Primetta eFaccioli   +9 more
doaj   +1 more source

How error correction affects polymerase chain reaction deduplication: A survey based on unique molecular identifier datasets of short reads

Quantitative Biology, Volume 13, Issue 3, September 2025.
Abstract Next‐generation sequencing data are widely utilised for various downstream applications in bioinformatics and numerous techniques have been developed for PCR‐deduplication and error‐correction to eliminate bias and errors introduced during the sequencing.
Pengyao Ping, Tian Lan, Shuquan Su, Wei Liu, Jinyan Li   +4 more
wiley   +1 more source

IsomiRage: from functional classification to differential expression of miRNAs and their isoforms

Frontiers in Bioengineering and Biotechnology, 2014
As more small RNA sequencing libraries are becoming available, it clearly emerges that microRNAs (miRNAs) are highly heterogeneous both in length and sequence.
heiko emuller, matteo jacopo marzi, Francesco eNicassio   +2 more
doaj   +1 more source

Comprehensive assessment of multiple biases in small RNA sequencing reveals significant differences in the performance of widely used methods

BMC Genomics, 2019
Background RNA sequencing offers advantages over other quantification methods for microRNA (miRNA), yet numerous biases make reliable quantification challenging.
Carrie Wright, Anandita Rajpurohit, Emily E. Burke, Courtney Williams, Leonardo Collado-Torres, Martha Kimos, Nicholas J. Brandon, Alan J. Cross, Andrew E. Jaffe, Daniel R. Weinberger, Joo Heon Shin   +10 more
doaj   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, Volume 599, Issue 13, Page 1821-1851, July 2025.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Circulating microRNAs and isomiRs as biomarkers for the initial insult and epileptogenesis in four experimental epilepsy models: The EPITARGET study

Epilepsia, Volume 65, Issue 11, Page 3406-3420, November 2024.
Abstract Objective Structural epilepsies can manifest months or years after the occurrence of an initial epileptogenic insult, making them amenable for secondary prevention. However, development of preventive treatments has been challenged by a lack of biomarkers for identifying the subset of individuals with the highest risk of epilepsy after the ...
Erwin A. van Vliet, Mirte Scheper, James D. Mills, Noora Puhakka, Kinga Szydlowska, Manuela Ferracin, Francesca Lovisari, Marie Soukupova, Silvia Zucchini, Prashant K. Srivastava, Michael R. Johnson, Katarzyna Lukasiuk, Jan A. Gorter, Eleonora Aronica, Asla Pitkänen, Michele Simonato   +15 more
wiley   +1 more source

Differential expression patterns of conserved miRNAs and isomiRs during Atlantic halibut development

BMC Genomics, 2012
Background MicroRNAs (miRNAs) play a major role in animal ontogenesis. Size variants of miRNAs, isomiRs, are observed along with the main miRNA types, but their origin and possible biological role are uncovered yet.
Bizuayehu Teshome T, Lanes Carlos FC, Furmanek Tomasz, Karlsen Bård O, Fernandes Jorge MO, Johansen Steinar D, Babiak Igor   +6 more
doaj   +1 more source

Differential levels of circulating RNAs prior to endometrial cancer diagnosis

International Journal of Cancer, Volume 155, Issue 5, Page 946-956, 1 September 2024.
What's new? While endometrial cancer (EC) is common among postmenopausal women, early detection is lacking, owing to an absence of effective screening strategies. Here, the authors explored circulating microRNAs (miRNAs) and changes in their abundance as markers for early EC detection.
Sina Rostami, Trine B. Rounge, Luca Pestarino, Robert Lyle, Renée Turzanski Fortner, Øystein Ariansen Haaland, Rolv T. Lie, Fredrik Wiklund, Tone Bjørge, Hilde Langseth   +9 more
wiley   +1 more source

A sliding-bulge structure at the Dicer processing site of pre-miRNAs regulates alternative Dicer processing to generate 5′-isomiRs

Heliyon, 2016
5′-isomiRs expand the repertoire of miRNA targets. However, how they are generated is not well understood. Previously, we showed that for some miRNAs in mammalian cells, Drosha cleaves at multiple sites to generate multiple pre-miRNAs that give rise to ...
Hongming Ma, Yonggan Wu, Qi Niu, Junli Zhang, Gengxiang Jia, N. Manjunath, Haoquan Wu   +6 more
doaj   +1 more source