Results 91 to 100 of about 97,287 (310)

Extensive transmission of isoniazid resistant M. tuberculosis and its association with increased multidrug-resistant TB in two rural counties of eastern China: A molecular epidemiological study

BMC Infectious Diseases, 2010
Background The aim of this study was to investigate the molecular characteristics of isoniazid resistant Mycobacterium tuberculosis (MTB), as well as its contribution to the dissemination of multi-drug resistant TB (MDR-TB) in rural areas of eastern ...
Wang Weibing, Jiang Weili, Hoffner Sven, Hu Yi, Xu Biao   +4 more
doaj   +1 more source

Post Penicillin Antibiotics: From acceptance to resistance? [PDF]

, 2000
Edited transcript of a Witness Seminar held at the Wellcome Institute for the History of Medicine, in London, on 12 May 1998. First published by the Wellcome Trust, 2000. ©The Trustee of the Wellcome Trust, London, 2000.
Reynolds, LA, Tansey, EM
core  

Acneiform dermatoses [PDF]

, 1998
Acneiform dermatoses are follicular eruptions. The initial lesion is inflammatory, usually a papule or pustule. Comedones are later secondary lesions, a sequel to encapsulation and healing of the primary abscess.
Jansen, Thomas, Plewig, G.
core   +1 more source

Tuberculous Retroperitoneal Lymphadenitis After Kidney Transplantation That Was Difficult to Diagnose and Treat: A Case Report

IJU Case Reports, EarlyView.
ABSTRACT Introduction We present a rare case of tuberculous retroperitoneal lymphadenitis after kidney transplantation that was difficult to diagnose and treat. Case Presentation A 52‐year‐old man who received a kidney transplantation from his wife presented with right lower quadrant pain.
Ryota Nakayasu, Yuki Kita, Yuki Teramoto, Kenji Nakamura, Toru Sakatani, Kimihiko Masui, Takayuki Goto, Ryoichi Saito, Takashi Kobayashi   +8 more
wiley   +1 more source

Inference without randomization or ignorability: A stability­ controlled quasi-experiment on the prevention of tuberculosis [PDF]

, 2019
When determining the effectiveness of a new treatment, randomized trials are not always possible or desirable. The stability-controlled quasi-experiment (SCQE) (Hazlett, 2019) is an observational approach that replaces the usual “no-unobserved confounding”
Hazlett, Chad, Maokola, Werner, Wulf, David Ami   +2 more
core  

ACCase 6 is the essential acetyl-CoA carboxylase involved in fatty acid and mycolic acid biosynthesis in mycobacteria [PDF]

, 2009
Mycolic acids are essential for the survival, virulence and antibiotic resistance of the human pathogen Mycobacterium tuberculosis. Inhibitors of mycolic acid biosynthesis, such as isoniazid and ethionamide, have been used as efficient drugs for the ...
Bazet Lyonnet, Bernardo, de la Iglesia, Agustina Inés, Gago, Gabriela Marisa, Gramajo, Hugo Cesar, Kurth, Daniel German, Lin, Ting Wang, Morbidoni, Héctor Ricardo, Tsai, Shiou Chuan   +7 more
core   +2 more sources

Is It an Intrapericardial Mass or a Localized Pericardial Effusion? A Case Report of Tuberculous Pericarditis Evaluated by Multimodal Imaging

Journal of Clinical Ultrasound, EarlyView.
Tuberculous pericarditis is a common type of pericarditis, but it is difficult to be diagnosed. The application of combined transesophageal echocardiography, contrast echocardiography, and CT multimodal imaging provides sufficient clinical diagnosis basis and guidance for distinguishing encapsulated pericardial effusion or mass.
Yang Han, Bingbing Liu, Yonghuai Wang, Fei Xia, Jun Yang, Chunyan Ma   +5 more
wiley   +1 more source

MmpL3 is the flippase for mycolic acids in mycobacteria [PDF]

, 2017
The defining feature of the mycobacterial outer membrane (OM) is the presence of mycolic acids (MAs), which, in part, render the bilayer extremely hydrophobic and impermeable to external insults, including many antibiotics.
Chng, Shu-Sin, Meshcheryakov, Vladimir A., Poce, Giovanna, Xu, Zhujun   +3 more
core   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Nevirapine versus Efavirenz for patients co-infected with HIV and Tuberculosis: A Randomised Non-Inferiority Trial [PDF]

, 2013
BACKGROUND: In countries with a high incidence of HIV and tuberculosis co-infection, nevirapine and efavirenz are widely used as antiretroviral therapy but both interact with antituberculosis drugs. We aimed to compare efficacy and safety of a nevirapine-
Agnès Sobry, Alexandra Calmy, Anne-Marie Taburet, Avihingsanon, Blackwelder, Boulle, Carlota Silva, Chen, Christine Rouzioux, Christophe Michon, Cohen, Cohen, Davies, Dejesus, Dieterich, Elisabeth Baudin, Elizabete Nunes, Flandre, Ford, Gengiah, Gulick, Ilesh Jani, Kwara, Laura Ciaffi, Maartens, Manosuthi, Manosuthi, Maryline Bonnet, Matteelli, Mbuagbaw, Meintjes, Nilesh Bhatt, Rui Bastos, Scourfield, Shipton, Soriano, Swaminathan, Tang, Telenti, van Leth   +39 more
core   +3 more sources