A Multinational Analysis of Mutations and Heterogeneity in PZase, RpsA, and PanD Associated with Pyrazinamide Resistance in M/XDR Mycobacterium tuberculosis. [PDF]
Pyrazinamide (PZA) is an important first-line drug in all existing and new tuberculosis (TB) treatment regimens. PZA-resistance in M. tuberculosis is increasing, especially among M/XDR cases.
Catanzaro, A +7 more
core +1 more source
Abstract Aims Child malnutrition remains a significant issue worldwide, particularly in developing regions like Asia. Age 6–23 months is critical for preventing malnutrition, yet numerous children within this range do not receive nutritionally sufficient complementary foods.
Intan Noor Hanifa +2 more
wiley +1 more source
Isoniazid-induced flu-like syndrome: A rare side effect
Drug-induced flu-like syndrome is very rare. It is mainly produced by rifampicin. We report a case of pulmonary tuberculosis (PTB) that developed isoniazid-induced flu-like syndrome, but could be cured with a modified regimen replacing isoniazid with ...
Sudipta Pandit +4 more
doaj +1 more source
New and Improved Diagnostics for Detection of Drug-Resistant Pulmonary Tuberculosis. [PDF]
PURPOSE OF REVIEW: Tuberculosis (TB) remains a global emergency and continues to kill 1.7 million people globally each year. Drug-resistant TB is now well established throughout the world and most TB patients are not being screened for drug resistance ...
Affolabi +41 more
core +1 more source
This study comprehended the allergen profiles of six edible crab species using proteomic and transcriptomic analyses and identified 11 putative allergens. King crab has a distinct protein and allergen profile, with the discovery of malate dehydrogenase as a novel king crab‐specific allergen registered as Para c 11.
Shanshan Li +11 more
wiley +1 more source
Antituberculosis Activity of Brotowali (Tinospora Crispa) Extract and Fractions Against Mycobacterium Tuberculosis Using Microplate Alamar Blue Assay Method [PDF]
Tuberculosis (TB), in which caused by pathogenic bacteria, Mycobacterium tuberculosis, has become the major causes of death among all of infectious diseases.
Irianti, T. (Tatang) +5 more
core
Paediatric Acute Generalised and Localised Exanthematous Pustulosis: A Systematic Review
JEADV Clinical Practice, EarlyView.
Miranda K. Branyiczky +6 more
wiley +1 more source
Synthesis and Characterization of pH-Sensitive Inulin Conjugate of Isoniazid for Monocyte-Targeted Delivery [PDF]
Franklin Afinjuomo +11 more
openalex +1 more source
The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley +1 more source
Background The activity of CYP2C9, an important drug metabolism enzyme, is subject to the impact of genetic polymorphism. The single nucleotide polymorphism *3 is significantly associated with the increased exposure of CYP2C9 substrates. In addition, metabolic enzyme inhibitors such as fluconazole may also increase the drug exposure of CYP2C9 ...
Shen Cheng +5 more
wiley +1 more source

