Results 101 to 110 of about 2,381,535 (223)

Influence of the Nature of the Cationic Residues on the Activity of the Antimicrobial Peptides of the Lynronne Family

Journal of Peptide Science, Volume 32, Issue 12, December 2026.
Derivatives of Lynronnes with cationic residues substitution were designed and tested in terms of antimicrobial activity, anti‐biofilm activity, mechanism of action, and in vitro toxicity. Lys‐substitution emerges as a promising strategy for improved activity and selectivity, particularly against E. coli. ABSTRACT Most antimicrobial peptides (AMPs) are
Alexis Reinbold, Maxime Gâchon, Jean‐François Cavalier, Laure Genet, Sophie Guillier, Mathilde Lescat, Muriel Serradeil‐Albalat, Linda B. Oyama, Cendrine Nicoletti, Sharon A. Huws, Nicolas Vidal, Fabiano Cavalcanti Fernandes, Andreia Gomes Martins, Stéphane Canaan, Octávio Luiz Franco, Sophie Tronnet, Olga Iranzo, Marc Maresca   +17 more
wiley   +1 more source

Genetic Characterization Conferred Co-Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis Isolates from Southern Xinjiang, China

, 2023
Bin Cao,1,2,* Xiaokaiti Mijiti,3,* Le-Le Deng,2,4 Quan Wang,3 Jin-Jie Yu,1,2 Aiketaguli Anwaierjiang,5 Chengyu Qian,2,6 Machao Li,2 Dan-Ang Fang,2,6 Yi Jiang,2 Li-Li Zhao,2 Xiuqin Zhao,2 Kanglin Wan,2 Haican Liu,2 Guilian Li,2 Xiuqin Yuan1 ...
Mijiti X, Liu H, Li G, Qian C, Cao B, Li M, Zhao X, Jiang Y, Wang Q, Anwaierjiang A, Zhao LL, Deng LL, Wan K, Yuan X, Fang DA, Yu JJ   +15 more
core  

Evaluation of GenoType MTBDRplus for the detection of drug-resistant Mycobacterium tuberculosis on isolates from Karachi, Pakistan.

PLoS ONE, 2019
ObjectiveTo compare the diagnostic performance of the GenoType MRBDRplus assay with the gold standard phenotypic drug susceptibility testing in the detection of drug resistance among culture isolates obtained from patients in Karachi, Pakistan ...
Sara Siddiqui, Meredith B Brooks, Amyn A Malik, Junaid Fuad, Ahsana Nazish, Safia Bano, Mercedes C Becerra, Hamidah Hussain   +7 more
doaj   +1 more source

Ceftriaxone‐induced liver injury: Incidence, phenotypic characterization and predictive factors

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3874-3885, November 2026.
Introduction Ceftriaxone is a widely used third‐generation cephalosporin in hospitalized patients. Although generally considered safe, it has been associated with hepatobiliary complications and emerging reports of drug‐induced liver injury (DILI). However, data on its true incidence, phenotypic patterns, and predictors remain limited. This study aimed
Mohamed Hatem, Mohannad N. AbuHaweeleh, Humam Emad Rajha, Mhd Osama Rahhal, Ahmad Hamdan, Lina Naseralallah   +5 more
wiley   +1 more source

Clinical Presentation Characteristics of Isoniazid (INH) Mono-Resistant Tuberculosis Cases by INH Resistance Group.

, 2012
Clinical Presentation Characteristics of Isoniazid (INH) Mono-Resistant Tuberculosis Cases by INH Resistance Group.
Raymund Dantes (163374), Midori Kato-Maeda (163386), Philip C. Hopewell (163396), Masae Kawamura (163405), Adithya Cattamanchi (121837), Elizabeth Kim (15121), Payam Nahid (163417), John Metcalfe (163378)   +7 more
core   +1 more source

Frequency of isoniazid resistance Mycobacterium tuberculosis isolates with minimum inhibitory concentration and line probe assay result.

, 2022
Frequency of isoniazid resistance Mycobacterium tuberculosis isolates with minimum inhibitory concentration and line probe assay result.
Russell R. Kempker (7348955), Gobena Ameni (357071), Dereje Beyene (5334734), Henry M. Blumberg (7348961), Muluwork Getahun (6744347)   +4 more
core   +1 more source

Multidrug-resistant and heteroresistant Mycobacterium tuberculosis and associated gene mutations in Ethiopia

International Journal of Infectious Diseases, 2015
Background: The prevalence of multidrug-resistant tuberculosis (TB) among new and retreatment cases in 2011 in Ethiopia was 2.7% and 17.9%, respectively.
Daniel Mekonnen, Aschalew Admassu, Wondemagegn Mulu, Aranzazu Amor, Agustín Benito, Woynshet Gelaye, Fantahun Biadglegne, Bayeh Abera   +7 more
doaj   +1 more source

Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3716-3732, November 2026.
Dolutegravir underpins modern first‐ and second‐line HIV treatment regimens; however, interindividual variability in its disposition and tolerability presents challenges for optimal use. This scoping review mapped current evidence on the pharmacogenomics of dolutegravir, focusing on pharmacokinetics and pharmacodynamics, and methodological limitations ...
Ronald Kiguba, Mishael Ssesanga, Munir Pirmohamed   +2 more
wiley   +1 more source

Speeding up the diagnosis of multidrug-resistant tuberculosis in a high-burden region with the use of a commercial line probe assay

Jornal Brasileiro de Pneumologia, 2019
Objective: To evaluate the rapid diagnosis of multidrug-resistant tuberculosis, by using a commercial line probe assay for rifampicin and isoniazid detection (LPA-plus), in the routine workflow of a tuberculosis reference laboratory.
Angela Pires Brandao, Juliana Maira Watanabe Pinhata, Rosangela Siqueira Oliveira, Vera Maria Neder Galesi, Helio Hehl Caiaffa-Filho, Lucilaine Ferrazoli   +5 more
doaj   +1 more source

Correction: Risk Factors for Acquired Rifamycin and Isoniazid Resistance: A Systematic Review and Meta-Analysis

, 2015
Correction: Risk Factors for Acquired Rifamycin and Isoniazid Resistance: A Systematic Review and Meta ...
PLOS ONE (2189197)
core   +1 more source