Results 91 to 100 of about 2,381,535 (223)

Negligible risk of inducing resistance in Mycobacterium tuberculosis with single-dose rifampicin as post-exposure prophylaxis for leprosy [PDF]

, 2016
Post-exposure prophylaxis (PEP) for leprosy is administered as one single dose of rifampicin (SDR) to the contacts of newly diagnosed leprosy patients. SDR reduces the risk of developing leprosy among contacts by around 60 % in the first 2-3 years after ...
Richard Anthony, Steinmann, P. (Peter), Mieras, Liesbeth, Bratschi, M W, Jan Hendrik Richardus, Kasang, C. (Christa), Arielle Cavaliero, Mieras, L. (Liesbeth), Lee Reichman, Jacques van den Broek, Cavaliero, A. (Arielle), Christa Kasang, Yew, W.W. (Wing Wai), Anthony, R, van Brakel, Wim, Reichman, L, Emmanuelle Cambau, Anthony, Richard, Steinmann, Peter, Perera, G, Saunderson, P. (Paul), Saunderson, Paul, Cavaliero, Arielle, Saunderson, P, Richardus, Jan hendrik; id_orcid, Kasang, Christa, van den Broek, Jacques, Kasang, C, Richardus, J.H. (Jan Hendrik), Cavaliero, A, Cambau, E. (Emmanuelle), Peter Steinmann, Anthony, R. (Richard), Yew, W W, Reichman, L. (Lee), Mieras, L, Yew, Wing Wai, Perera, G. (Geethal), Richardus, Jan Hendrik, Wim van Brakel, Brakel, W.H. (Wim) van, Bratschi, M.W. (Martin W.), Paul Saunderson, van Brakel, W, Cambau, E, Reichman, Lee, van den Broek, J, Bratschi, Martin W., Steinmann, P, Cambau, Emmanuelle, Geethal Perera, Wing Wai Yew, van den Broek, J. (Jacques), Perera, Geethal, Liesbeth Mieras, Martin W. Bratschi   +55 more
core   +1 more source

Feasibility and clinical outcomes of routine point‐of‐care screening for opportunistic infections among people with advanced HIV disease in Guyana

HIV Medicine, EarlyView.
Abstract Objectives We evaluated the feasibility and outcomes of implementing comprehensive Point‐of‐care (POC) opportunistic infections (OIs) screening among people with Advanced HIV disease (AHD) in Guyana. Methods We conducted a prospective multicentre cohort study across seven sites between February 2024 and March 2025.
Antonio Camiro‐Zúñiga, Tariq Jagnarine, Divya Shivdas, Lakshmi Narain, Kwesi Vanccoten, Kampta Prashad, Abiola Jacobs, Quacy Grant, Mallika Mootoo, Narissa Lawerence, Suzanne Siebs, Escalada Rainier, Omar Sued, Freddy Perez   +13 more
wiley   +1 more source

Implementation of tuberculosis intensive case finding, isoniazid preventive therapy, and infection control ("Three I's") and HIV-tuberculosis service integration in lower income countries [PDF]

, 2016
World Health Organization advocates for integration of HIV-tuberculosis (TB) services and recommends intensive case finding (ICF), isoniazid preventive therapy (IPT), and infection control ("Three I's") for TB prevention and control among persons living ...
M Katherine Charles, Barbara Castelnuovo (10700), Nguyen Thi Dung, Divine Avit-Edi, Cortés Moncada, Claudia, IeDEA, Ballif, Marie, Nakigozi, Gertrude, Marie Ballif, Durier, Nicolas, Dusingize, Jean Claude, Charles, M Katherine, Nguyen, Thi Dung, Wester, C William, ,, Meridith Blevins, Dung, Nguyen Thi, Cortes, Claudia P, Cortes, Claudia P., Fenner, Lukas, C William Wester, Wester, C. William, Jean Claude Dusingize (473718), Divine Avit-Edi (2609464), Claudia P. Cortes (473719), Mary Lou Lindegren (2609461), Lindegren, Mary Lou, Gertrude Nakigozi, Charles, M. Katherine, Gertrude Nakigozi (247948), C. William Wester (250717), Timothy R. Sterling (148936), Lukas Fenner, Marie Ballif (368655), Blevins, Meridith, Nicolas Durier (326615), Jean Claude Dusingize, Claudia P Cortes, Avit-Edi, Divine, Sterling, Timothy R., Nguyen Thi Dung (245054), Nicolas Durier, Castelnuovo, Barbara, Timothy R Sterling, International epidemiology Databases to Evaluate AIDS (IeDEA) Collaboration, Mary Lou Lindegren, Barbara Castelnuovo, Lukas Fenner (149822), Sterling, Timothy R, Meridith Blevins (291088), M. Katherine Charles (2609458), Sterling TR, Ballif M, Castelnuovo B, Fenner L, Blevins M, Charles MK, Avit-Edi D, Durier N, Cortes CP, Nakigozi G, Wester CW, Lindegren ML, Dung NT, Dusingize JC   +64 more
core   +3 more sources

Mutations conferring resistance to first-line anti-tuberculosis drugs in Peru: a systematic review of the literature

Revista Peruana de Medicina Experimental y Salud Pública, 2019
Objective. To systematize available information regarding mutations that confer resistance to first-line anti-tuberculosis drugs. Materials and Methods.
Aiko Vigo, Lely Solari, David Santos, Zully M. Puyén   +3 more
doaj   +1 more source

Patterns of Drug Resistance, Drug Resistance Conferring Mutations and Genomic DNA Methylation Revealed in Mycobacterium tuberculosis From South Africa

Tropical Medicine &International Health, EarlyView.
ABSTRACT Tuberculosis remains a major public health threat globally, with drug‐resistant strains undermining treatment efficacy. We analyzed 126 Mycobacterium tuberculosis (M. tuberculosis) isolates with diverse drug resistance spectra and selected 35 for whole genome sequencing (WGS) using Illumina NextSeq, SMRT PacBio Onso and SMRT PacBio Revio ...
Unarine Matodzi, Awelani Mutshembele, Eric Mensah, Dillon Muzondiwa, Ndivhuho A. Makhado, Oleg N. Reva   +5 more
wiley   +1 more source

Pyroptosis in Preeclampsia: Placenta‐to‐Maternal Organ Communication, Molecular Mechanisms, and Therapeutic Targets

Comprehensive Physiology, Volume 16, Issue 6, December 2026.
Schematic diagram illustrating the potential mechanisms and core molecules contributing to the development of PE via mediating pyroptosis: focus on trophoblasts and endothelial cells. Pyroptosis of trophoblast cells in the placenta of preeclampsia not only inhibits its invasion, migration, and differentiation, causing local infiltration and ...
Xianyi Zhou, Liming Yuan, Ya Li, Rong Zhou, Linbo Gao, Xiaohong Wei   +5 more
wiley   +1 more source

Mutations responsible for Mycobacterium tuberculosis isoniazid resistance in Italy

, 2005
SETTING: The incidence of tuberculosis as well as drug resistance in Italy is low as compared to other countries. Isoniazid is a frontline drug for the treatment of tuberculosis.
GARZELLI C., RINDI, LAURA, D. BONANNI, GARZELLI, CARLO, L. BIANCHI, E. TORTOLI   +5 more
core  

Epidemiology of isoniazid resistance mutations and their effect on tuberculosis treatment outcomes. [PDF]

, 2013
Isoniazid resistance is highly prevalent in Vietnam. We investigated the molecular and epidemiological characteristics and the association with first-line treatment outcomes of the main isoniazid resistance mutations in Mycobacterium tuberculosis in ...
Soolingen, D. van, Cobelens, F.G., Lan, N.T., Dung, N.H., Huyen, M.N., Buu, T.N., Kremer, K., Tiemersma, E.W.   +7 more
core   +1 more source

The Course of Pulmonary Tuberculosis in Patients Excreting Organisms which have Acquired Resistance to Isoniazid: Response to Continued Treatment for a Second Year with Isoniazid Alone or with Isoniazid plus PAS [PDF]

, 1962
This study from the Tuberculosis Chemotherapy Centre, Madras, summarizes the progress during the second year of the patients in a concurrent comparison of four domiciIiary chemotherapeutic regimens (isoniazid plus PAS and three regimens of isoniazid ...
Devadatta, S, Ramakrishnan, C V, Selkon, J B, Bhatia, A L, Narayana, A S L, Fox, Wallace, Velu, S   +6 more
core   +1 more source

Isoniazid-Resistant Tuberculosis, Taiwan, 2000-2010

Emerging Infectious Diseases, 2011
To the Editor: Vinnard et al. (1) reported that the risk factors associated with initial isoniazid resistance among patients with tuberculous meningitis in the United States during 1993–2005 included young age (25–34 years) and foreign birth (1). In a previous survey, conducted in Taiwan during 2000–2008, we found the rate of antituberculosis drug ...
Chih-Cheng Lai, Che-Kim Tan, Yu-Tsung Huang, Chun-Hsing Liao, Po-Ren Hsueh   +4 more
openaire   +3 more sources