Results 71 to 80 of about 2,381,535 (223)

Health risk assessment of heavy metal accumulation in fruits exposed to geothermal waters: a case study and global implications

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND The present study investigated the potential health risks of heavy metals (HMs) in the fruits and leaves of mulberry and sour cherry trees exposed to water from Sivas geothermal basin (Turkey). RESULTS The target HMs were ranked according to their hazard index as: Cd < Pb < Zn < Cu < Ni < Mn < Cr. The total hazard index for mulberry
E Işıl Arslan Topal, Murat Topal, Erdal Çelik, Erdal Öbek   +3 more
wiley   +1 more source

Elucidating Isoniazid Resistance Using Molecular Modeling

, 2016
The continuing rise in tuberculosis incidence and the problem of drug resistance strains have prompted the research on new drug candidates and the mechanism of drug resistance.
Amirin Sadikun (2396059), Yee-Siew Choong (2396065), Pazilah Ibrahim (2396062), Thomas Scior (497767), Habibah A. Wahab (1425556)   +4 more
core   +1 more source

Response to treatment with isoniazid plus PAS of tuberculous patients with primary isoniazid resistance

, 1969
The response to treatment with isoniazid plus PAS was studied in 30 patients with primary isoniazid resistance and 459 patients with initially isoniazid-sensitive cultures.
Stott, H, Tripathy, S P, Menon, N K, Narayana, A S L, Somasundaram, P R, Mitchison, D A, Velu, S   +6 more
core   +1 more source

A cross-sectional study on the factors influencing drug resistance in clinical Mycobacterium tuberculosis in Hulunbuir, Inner Mongolia [PDF]

Srpski Arhiv za Celokupno Lekarstvo
Introduction/Objective. This study aimed to improve the understanding of drug-resistant tuberculosis (TB) by conducting a retrospective analysis of clinical data from TB patients in Hulunbuir, Inner Mongolia, collected between 2015 and 2017. Methods.
Guo Huijun, Yu Yanqin, Hao Jinqi, Zhang Lan, Hao Mingyuan   +4 more
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Association between body mass index and newly diagnosed drug-resistant pulmonary tuberculosis in Shandong, China from 2004 to 2019

BMC Pulmonary Medicine, 2021
Background Drug-resistant tuberculosis (DR-TB), obesity, and malnutrition are growing public health problems in the world. However, little has discussed the impact of different BMI status on the emergence of TB drug resistance.
Wan-mei Song, Jing Guo, Ting-ting Xu, Shi-jin Li, Jin-yue Liu, Ning-ning Tao, Yao Liu, Qian-yun Zhang, Si-qi Liu, Qi-qi An, Yi-fan Li, Chun-bao Yu, Ji-hua Dong, Huai-chen Li   +13 more
doaj   +1 more source

Integration of scRNA‐Seq and scATAC‐Seq Revealed the Role of lncRNA RP11‐661C8.2 by Promoting EMT in Clear Cell Renal Cell Carcinoma

Molecular Carcinogenesis, EarlyView.
ABSTRACT Long noncoding RNAs (lncRNAs) play an important role in tumor progression. However, most of the previously discovered lncRNAs that promote or inhibit tumor progression were derived from bulk RNA‐seq results. Data from single‐cell RNA sequencing (scRNA‐seq) and single‐cell assay for transposase‐accessible chromatin using sequencing (scATAC‐seq)
Jizhen Cen, Xuefang Liang, Zheng Wen, Shengzhu Huang, Jiaping Li, Haibiao Yan, Kaiqiang Tang, Guifen Zhou, Ning Liang, Qi Zheng, Cheng Su, Zengnan Mo, Zhenyuan Yu   +12 more
wiley   +1 more source

Treatment outcomes of high- and low-level isoniazid-resistant tuberculosis: Analysis from a Nationwide Pulmonary Tuberculosis Cohort

International Journal of Infectious Diseases
Objectives: Isoniazid resistance is the most common first-line drug resistance in tuberculosis (TB) and is associated with poor outcomes when standard therapy is used.
Chia-Hao Chang, Ming-Chia Lee, Li-Ta Keng, Jin-Hua Chen, Meng-Rui Lee, Chih-Hsin Lee, Jann-Yuan Wang   +6 more
doaj   +1 more source

High Prevalence of inhA Promoter Mutations among Patients with Drug-Resistant Tuberculosis in KwaZulu-Natal, South Africa.

PLoS ONE, 2015
BackgroundDrug-resistant tuberculosis (TB) remains extremely difficult to treat because there are often few remaining active medications and limited diagnostic options to detect resistance.
Abraham J Niehaus, Koleka Mlisana, Neel R Gandhi, Barun Mathema, James C M Brust   +4 more
doaj   +1 more source

Resistance patterns of Mycobacterium tuberculosis isolates from pulmonary tuberculosis patients in Nairobi

Journal of Infection in Developing Countries, 2011
Introduction: In Kenya, which ranks thirteenth of 27 high tuberculosis burden countries, diagnosis is based on Ziehl-Neelsen staining alone and patients are treated without information on sensitivity patterns.
Perpetual Wangui Ndung'u, Samuel Kariuki, Zipporah Ng'ang'a, Gunturu Revathi   +3 more
doaj   +1 more source