Results 61 to 70 of about 2,381,535 (223)
PLoS ONE, 2013 BackgroundDevelopment of resistance to antituberculosis drugs during treatment (i.e., acquired resistance) can lead to emergence of resistant strains and consequent poor clinical outcomes. However, it is unknown whether Mycobacterium tuberculosis complex
Courtney M Yuen +4 more
doaj +1 more source
Annona squamosa: Phytochemical Fingerprinting, Health‐Improving Traits, and Functional Applications
Food Chemistry International, EarlyView.Annona squamosa (custard apple) is a nutrient‐rich fruit containing diverse bioactive phytochemicals (e.g., acetogenins, flavonoids, and alkaloids) that contribute to multiple health benefits, including antioxidant, antihyperlipidemic, and antimicrobial activities, highlighting its potential as a functional food and medicinal resource.
Mohamed Fawzy Ramadan +4 more
wiley +1 more source
, 2016 Isoniazid is an antituberculosis prodrug that requires activation by the catalase-peroxidase (KatG) of Mycobacterium tuberculosis. The activated species, presumed to be an isonicotinoyl radical, couples to NADH forming an isoniazid−NADH adduct that ...
Frank M. Rusnak (2669485) +3 more
core +2 more sources
GenoType MTBDRplus Assay for Rapid Detection of Multidrug Resistance in Mycobacterium tuberculosis: A Meta-Analysis. [PDF]
PLoS ONE, 2016 BACKGROUND:There is an urgent demand for rapid and accurate drug-susceptibility testing for the detection of multidrug-resistant tuberculosis. The GenoType MTBDRplus assay is a promising molecular kit designed for rapid identification of resistance to ...
Yuanyuan Bai +4 more
doaj +1 more source
, 2019 Anti-tubercular therapy is one of the effective strategies used to control tuberculosis, so, a planned and accurate treatment regimen is of utmost importance, but number of cases are being treated as MDR on the basis of rifampicin mono resistance.
Mazhar Maqsood, Sana Nudrat, Umar Farooq
core +1 more source
Journal of Clinical Laboratory Analysis, EarlyView.This large retrospective study compared the diagnostic performance of three commercial real‐time PCR assays (AdvanSure TB/NTM, Cobas MTB, and Xpert MTB/RIF) for MTBC detection in 3348 bronchial washing specimens. In a head‐to‐head comparison of 740 specimens, the Cobas MTB and Xpert MTB/RIF assays showed markedly higher sensitivity than the AdvanSure ...
Jimyung Kim, Yumi Park
wiley +1 more source
Safety of long-term isoniazid preventive therapy in children with HIV [PDF]
, 2014 Includes bibliographical references.Tuberculosis (TB) and HIV co-infection is association with significant morbidity and mortality, especially in young children.
Le Roux, Stanzi Maria
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Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley +1 more source
Prevalence (%) of isoniazid resistance among new and previously treated TB cases by WHO region.
, 2020 Prevalence (%) of isoniazid resistance among new and previously treated TB cases by WHO region.
Nazir Ismail (602087) +15 more
core +1 more source
[A case of isoniazid-resistant tuberculosis diagnosed during chemoprophylaxis with isoniazid].
Kekkaku : [Tuberculosis], 2001 A 15-year-old man, who was a classmate with the index case of a large outbreak of tuberculosis in a junior high school in Kochi city, showed strongly positive reaction to tuberculin skin test in March 1999. After taking a chest X-ray film, which showed no abnormal finding, chemoprophylaxis with isoniazid was started in April 1999. He was compliant with
TOYOTA, Makoto, MORIOKA, Shigeharu
openaire +2 more sources