Results 51 to 60 of about 2,381,535 (223)

Design and Performance of a High‐Efficiency Inhibitor: Synergistic Effect of Modified Chitosan and Boron Nitride Nanosheets on Steel Protection

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Metal corrosion causes significant economic losses and safety hazards, underscoring the urgent need for effective, environmentally friendly corrosion inhibitors. In this study, an organic–inorganic composite inhibitor, chitosan–glucose–BN (CS–GL–BN) was developed to protect Q235 mild steel in a 3.5‐wt% NaCl solution.
Shanjun Xu, Bing Xia, Penghang Yan, Deqing Kong, Dong Li   +4 more
wiley   +1 more source

Evaluating the performance of the InnowaveDx MTB/RIF/INH for simultaneous detection of Mycobacterium tuberculosis and resistance to rifampicin and isoniazid

Journal of Global Antimicrobial Resistance
Objective: To evaluate the diagnostic performance of the InnowaveDx MTB/RIF/INH assay for the simultaneous detection of Mycobacterium tuberculosis and resistance to rifampicin and isoniazid. Methods: We evaluated the performance of the InnowaveDx MTB/RIF/
Dapeng Fan, Hao Li, Xuechai Shang, Miaofen Yang, Huanyu Li, Yongning Yue, Long Cai   +6 more
doaj   +1 more source

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

Novel benzimidazole TREA‐0247 as non‐peptidic allosteric EGFR L858R/T790M/C797S inhibitor

Bulletin of the Korean Chemical Society, EarlyView.
A novel non‐peptidic EGFR allosteric inhibitor TREA‐0247 is disclosed. TREA‐0247 contains 5‐chloro‐2‐hydroxyl phenyl along with the benzimidazole core and its molecular interaction is also discussed. Abstract Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) improve overall survival rate in patients with EGFR mutated non‐small ...
Jiwon Kim, Seoyoung Lee, Chang Hak Chae, Gildon Choi, Byoung Chul Cho, Kwangho Lee   +5 more
wiley   +1 more source

Percentage of all, new and retreatment TB cases with isoniazid resistance by WHO region.

, 2013
Percentage of (a) all TB cases, (b) new TB cases and (c) retreatment TB cases with any resistance to isoniazid, resistance to isoniazid but not rifampin and multi-drug resistance by WHO region (AFR =  African region, AMR =  region for the Americas, EMR = 
Helen E. Jenkins (307031), Matteo Zignol (94959), Ted Cohen (118302)   +2 more
core   +1 more source

Impact of isoniazid monoresistance on overall and vulnerable patient populations in Taiwan

Emerging Microbes and Infections
Isoniazid is an early bactericidal anti-tuberculosis (TB) agent and isoniazid mono-resistance TB is the most prevalent drug-resistant TB worldwide. Concerns exist regarding whether resistance to isoniazid would lead to delayed culture conversion and ...
Meng-Rui Lee, Li-Ta Keng, Ming-Chia Lee, Jin-Hua Chen, Chih-Hsin Lee, Jann-Yuan Wang   +5 more
doaj   +1 more source

Evaluation of Geno Type MTBDRplus Line Probe Assay for Early Detection of Drug Resistance in Tuberculous Meningitis Patients in India

Journal of Global Infectious Diseases, 2015
Background: Molecular methods which allow for rapid and reliable detection of drug resistance have yet not been sufficiently evaluated for timely management of patients with tuberculous meningitis.
Renu Gupta, Rajeev Thakur, Prerna Gupta, Nupur Jalan, Suman Kushwaha, Meena Gupta, Piyush Gupta, Amitesh Aggarwal, Vikas Manchanda   +8 more
doaj   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Evaluation of High-Dose Isoniazid in Multidrug-Resistant Tuberculosis Treatment

Emerging Infectious Diseases
High-dose isoniazid is recommended to treat multidrug-resistant tuberculosis (MDR TB). Among 958 MDR TB isolates identified in France during 2008–2022, 93.1% exhibited high-level isoniazid resistance, and molecular testing showed limited diagnostic ...
Valentina Gerussi, Tania Petersen, Isabelle Bonnet, Alexandra Aubry, Marwa Bachir, Esther Gyde, Florence Morel, Corentin Poignon, Brigitte Rached, Valérie Pourcher, Christophe Rioux, Dorothée Vallois, Nicolas Veziris, Jérôme Robert, Lorenzo Guglielmetti   +14 more
doaj   +1 more source

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source