Results 31 to 40 of about 26,580 (200)

Chemical Isoprenoid Synthases and Uses Thereof [PDF]

open access: yes, 2000
Disclosed is a chimeric isoprenoid synthase polypeptide including a first domain from a first isoprenoid synthase joined to a second domain from a second, heterologous isoprenoid synthase, whereby the chimeric isoprenoid synthase is capable of catalyzing
Back, Kyoungwhan, Chappell, Joseph
core   +1 more source

Enhanced ER-associated degradation of HMG CoA reductase causes embryonic lethality associated with Ubiad1 deficiency

open access: yeseLife, 2020
UbiA prenyltransferase domain-containing protein-1 (UBIAD1) synthesizes the vitamin K subtype menaquinone-4 (MK-4). Previous studies in cultured cells (Schumacher et al., 2015) revealed that UBIAD1 also inhibits endoplasmic reticulum (ER)-associated ...
Youngah Jo   +9 more
doaj   +1 more source

Metabolic engineering of isoprenoid production: Reconstruction of multistep heterologous pathways in tractable hosts

open access: yes, 2013
Isoprenoids represent a wide group of chemically active compounds that can find a wide range of applications as flavors, perfumes, vitamins, nutraceuticals, and pharmaceuticals.
Asadollahi, M. A.,   +12 more
core   +1 more source

Phosphomevalonate kinase is a cytosolic protein in humans

open access: yesJournal of Lipid Research, 2004
In the past decade, a predominant peroxisomal localization has been reported for several enzymes functioning in the presqualene segment of the cholesterol/isoprenoid biosynthesis pathway.
Sietske Hogenboom   +5 more
doaj   +1 more source

Diversifying Isoprenoid Platforms via Atypical Carbon Substrates and Non-model Microorganisms

open access: yesFrontiers in Microbiology, 2021
Isoprenoid compounds are biologically ubiquitous, and their characteristic modularity has afforded products ranging from pharmaceuticals to biofuels. Isoprenoid production has been largely successful in Escherichia coli and Saccharomyces cerevisiae with ...
David N. Carruthers   +3 more
doaj   +1 more source

Isoprenoid GDGTs in Lake Challa sediments

open access: yes, 2012
Isoprenoid GDGTs in Lake Challa ...
Schouten, Stefan   +7 more
core   +1 more source

Chimeric Isoprenoid Synthases and Uses Thereof [PDF]

open access: yes, 2012
Disclosed is a chimeric isoprenoid synthase polypeptide including a first domain from a first isoprenoid synthase joined to a second domain from a second, heterologous isoprenoid synthase, whereby the chimeric isoprenoid synthase is capable of catalyzing
Back, Kyoungwhan, Chappell, Joe
core   +1 more source

Volatile isoprenoid emission potentials are correlated with essential isoprenoid concentrations in five plant species [PDF]

open access: yes, 2013
This study offers new insight and data in support of the “opportunist hypothesis”. Five species of volatile isoprenoid-emitting plants (Eucalyptus globulus, Eucalyptus gunnii, Mucuna pruriens, Lycopersicon esculentum and Quercus ilex) were exposed to a ...
Owen, Susan Margaret, Penuelas, Josep
core   +1 more source

Tocopherol biosynthesis in Leishmania (L.) amazonensis promastigotes

open access: yesFEBS Open Bio, 2019
Leishmaniasis is a neglected disease caused by a trypanosomatid protozoan of the genus Leishmania. Most drugs used to treat leishmaniasis are highly toxic, and the emergence of drug‐resistant strains has been observed.
José Mário F. Balanco   +5 more
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

open access: yesAdvanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li   +7 more
wiley   +1 more source

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