Results 1 to 10 of about 383 (148)
Frontiers in Plant Science, 2022 It is critical to develop plant isoprenoid production when dealing with human-demanded industries such as flavoring, aroma, pigment, pharmaceuticals, and biomass used for biofuels.
Ali Movahedi +2 more
exaly +3 more sources
Shortcut for isoprenoid biosynthesis [PDF]
Nature Catalysis, 2019 Voller Jan-Stefan, Jan‐Stefan Voller
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Diversifying Isoprenoid Platforms via Atypical Carbon Substrates and Non-model Microorganisms
Frontiers in Microbiology, 2021 Isoprenoid compounds are biologically ubiquitous, and their characteristic modularity has afforded products ranging from pharmaceuticals to biofuels. Isoprenoid production has been largely successful in Escherichia coli and Saccharomyces cerevisiae with ...
David N. Carruthers +3 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2022 (E)-4-hydroxy-3-methylbut-2-enyl pyrophosphate (HMBPP) reductase (IspH) is a [4Fe-4S] cluster-containing enzyme, involved in isoprenoid biosynthesis as the final enzyme of the methylerythritol phosphate (MEP) pathway found in many bacteria and malaria ...
Shiyong Huang +4 more
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Growth-uncoupled isoprenoid synthesis in Rhodobacter sphaeroides
Biotechnology for Biofuels, 2020 Background Microbial cell factories are usually engineered and employed for cultivations that combine product synthesis with growth. Such a strategy inevitably invests part of the substrate pool towards the generation of biomass and cellular maintenance.
Enrico Orsi +8 more
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Distinct Peculiarities of In Planta Synthesis of Isoprenoid and Aromatic Cytokinins
Biomolecules, 2020 The biosynthesis of aromatic cytokinins in planta, unlike isoprenoid cytokinins, is still unknown. To compare the final steps of biosynthesis pathways of aromatic and isoprenoid cytokinins, we synthesized a series of nucleoside derivatives of natural ...
Vladimir E. Oslovsky +4 more
doaj +1 more source
Frontiers in Plant Science, 2022 Programmed cell death (PCD), a characteristic feature of hypersensitive response (HR) in plants, is an important cellular process often associated with the defense response against pathogens.
Sanghun Lee +7 more
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Downregulation of Squalene Synthase Broadly Impacts Isoprenoid Biosynthesis in Guayule
Metabolites, 2022 Production of natural rubber by Parthenium argentaum (guayule) requires increased yield for economic sustainability. An RNAi gene silencing strategy was used to engineer isoprenoid biosynthesis by downregulation of squalene synthase (SQS), such that the ...
Dante Placido +8 more
doaj +1 more source
Isoprenoid Biosynthesis in Plasmodium falciparum [PDF]
Eukaryotic Cell, 2014 ABSTRACT Malaria kills nearly 1 million people each year, and the protozoan parasite Plasmodium falciparum has become increasingly resistant to current therapies. Isoprenoid synthesis via the methylerythritol phosphate (MEP) pathway represents an attractive target for the development of new antimalarials ...
Guggisberg, Ann M +2 more
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Role of Peroxisomes in Isoprenoid Biosynthesis [PDF]
Journal of Histochemistry & Cytochemistry, 1999 Our group and others have recently demonstrated that peroxisomes contain a number of enzymes involved in cholesterol biosynthesis that previously were considered to be cytosolic or located in the endoplasmic reticulum (ER). Peroxisomes have been shown to contain HMG-CoA reductase, mevalonate kinase, phosphomevalonate kinase, phosphomevalonate ...
N, Aboushadi +3 more
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