Results 131 to 140 of about 59,651 (334)

Shedding Light on the Cellular Uptake Mechanisms of Bioactive Glass Nanoparticles as Controlled Intracellular Delivery Platforms: A Review of the Recent Literature

Advanced Healthcare Materials, EarlyView.
This review summarizes the main uptake pathways of bioactive glass nanoparticles (BGNs) and their intracellular localization, highlighting that BGNs are mainly internalized and entrapped within endosomes/lysosomes. Strategies for controlled intracellular ion release, with implications for targeted modulation of cell behavior, are discussed. The need to
Andrada‐Ioana Damian‐Buda, Aldo R. Boccaccini   +1 more
wiley   +1 more source

Hydrogen Sulfide (H₂S) Releasing Capacity of Isothiocyanates from Moringa oleifera Lam.

Molecules, 2018
Moringa oleifera Lam. is rich in phytochemical compounds especially glucosinolates (GSs) and isothiocyanates (ITCs), which are active compounds for cancer chemoprevention benefits of Brassicaceae vegetables.
Xiangshe Wang, Yunjiao Liu, Xingdi Liu, Yi Lin, Xueqin Zheng, Yuyun Lu   +5 more
doaj   +1 more source

Isothiocyanates as effective agents against enterohemorrhagic Escherichia coli: insight to the mode of action

Scientific Reports, 2016
Production of Shiga toxins by enterohemorrhagic Escherichia coli (EHEC) which is responsible for the pathogenicity of these strains, is strictly correlated with induction of lambdoid bacteriophages present in the host’s genome, replication of phage DNA ...
D. Nowicki, Olga Rodzik, A. Herman-Antosiewicz, A. Szalewska-Pałasz   +3 more
semanticscholar   +1 more source

SaxA-Mediated Isothiocyanate Metabolism in Phytopathogenic Pectobacteria [PDF]

, 2016
Cornelia U. Welte, Jamila Franca Rosengarten, Rob M. de Graaf, Mike S. M. Jetten   +3 more
openalex   +1 more source

Metronidazole‐Loaded Cyclodextrin Nanogels for Antibacterial Therapy and Microbiota Regulation in Periodontitis

Advanced Healthcare Materials, EarlyView.
A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji, Ruichen Zhang, Dongyi Xu, Patrick C. A. van der Wel, Alessia Lasorsa, Guotai Li, Fangze Guo, Qihui Zhou, Patrick van Rijn   +8 more
wiley   +1 more source

Effect of Heavy Metal Ions and Carbohydrates on the Activity of Cauliflower (Brassica oleracea Var. botrytis) Myrosinase [PDF]

, 2013
Myrosinase is an enzyme of cruciferous vegetables, hydrolyse glucosinolates. The breakdown products are involved in plant defence against insect and also have anti-fungal property.
Prakash, Om, Rai, Ajeet Kumar, Singh, Jagdish, Singh, P. M.   +3 more
core  

Metabolic Activity of Radish Sprouts Derived Isothiocyanates in Drosophila melanogaster

International Journal of Molecular Sciences, 2016
We used Drosophila melanogaster as a model system to study the absorption, metabolism and potential health benefits of plant bioactives derived from radish sprouts (Raphanus sativus cv.
N. Baenas, Stefanie Piegholdt, Anke Schloesser, D. Moreno, C. García‐Viguera, G. Rimbach, A. E. Wagner   +6 more
semanticscholar   +1 more source

Porous Coatings by Vapor Sublimation and Deposition for Molecular Channeling and Filtration in an Interstitial Fluid Microfiltration Device

Advanced Healthcare Materials, EarlyView.
A vapor‐based porous coating applied within nitinol tubes demonstrated complete suppression of cellular and tissue ingrowth, overcoming a major limitation of implantable interstitial fluid collection devices. Molecular channeling and diffusion are analyzed with probe molecules, showing reliable transport in vitro and in vivo. The coating also achieved >
Yu‐Ming Chang, Chi‐Yu Huang, Yi‐Jia Ke, Yi‐Wei Lin, Yen‐Hui Chan, Ying‐Chang Lu, Yu‐Chih Chiang, Chen‐Chi Wu, Hsien‐Yeh Chen   +8 more
wiley   +1 more source

Nanodelivery of Natural Isothiocyanates as a Cancer Therapeutic.

Free Radical Biology & Medicine, 2021
Qi Wang, Y. Bao
semanticscholar   +1 more source

Synthesis of 6-Phosphorylated Phenanthridines by Mn(II)-Promoted Tandem Reactions of 2-Biaryl Isothiocyanates with Phosphine Oxides.

Journal of Organic Chemistry, 2017
A novel Mn(II)-promoted tandem phosphorylation/cyclization reaction of 2-biaryl isothiocyanates with phosphine oxides is described. This is the first general method to synthesize 6-phosporylated phenanthridines from 2-biaryl isothiocyanates. The approach
Weisi Guo, Qian Dou, Jian‐Guo Hou, L. Wen, Ming Li   +4 more
semanticscholar   +1 more source