Synthesis and characterization of selected fused isoxazole and pyrazole derivatives and their antimicrobial activity [PDF]
Journal of the Serbian Chemical Society, 2009 New potent antibacterials, fused isoxazole and pyrazole derivatives, were synthesized using 5,5-dimethylcyclohexane-1,3-dione (1) and 3-[(4-chlorobenzylidene) amino]-2-thioxoimidazolidin-4-one (2) as synthons.
Dabholkar Vijay V., Ansari Faisal Y.
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1-Methyl-3-(2-methylphenyl)-3,3a,4,9b-tetrahydro-1H-chromeno[4,3-c][1,2]oxazole-3a-carbonitrile [PDF]
Acta Crystallographica Section E, 2011 In the title compound, C19H18N2O2, the five-membered isoxazole ring adopts an envelope conformation and the deviation of the N atom from the mean plane of the isoxazole ring is −0.3256 (11) Å.
K. Swaminathan +3 more
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1-Methyl-3-p-tolyl-3,3a,4,9b-tetrahydro-1H-chromeno[4,3-c]isoxazole-3a-carbonitrile [PDF]
Acta Crystallographica Section E, 2011 In the title compound, C19H18N2O2, the dihedral angle between the mean planes of the fused chromeno and isoxazole units is 43.71 (7)°. The isoxazole and pyran rings exhibit envelope and half chair conformations, respectively.
Rajeswari Gangadharan +3 more
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4-(4-Chlorophenyl)-5-phenylisoxazole [PDF]
Acta Crystallographica Section E, 2009 The title compound, C15H10ClNO, is a functionalized isoxazole with a chlorophenyl and a phenyl substitutent. The mean plane of the isoxazole ring is inclined to those of the two benzene ring mean planes by 38.32 (16) and 43.91 (18 ...
M. Krishnaiah +3 more
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4-(4-Fluorophenyl)-2-methyl-3-(1-oxy-4-pyridyl)isoxazol-5(2H)-one [PDF]
Acta Crystallographica Section E, 2008 The crystal structure of the title compound, C15H11FN2O3, was determined as part of a study on the biological activity of isoxazolone derivatives as p38 mitogen-activated protein kinase (MAPK) inhibitors.
Stefan Laufer +2 more
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2,10-Bis(3-bromophenyl)-3,7,11,15-tetraoxa-8,16-diazatricyclo[12.2.1.16,9]octadeca-1(16),6(18),8,14(17)-tetraene [PDF]
Acta Crystallographica Section E, 2010 The title compound, C24H20Br2N2O4, is an 18-membered tricycle including two isoxazole rings. The asymmetric unit contains one half of the formula unit; a centre of inversion is located at the centroid of the compound.
Kwang Ha +3 more
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Methyl 3-(4-isopropylphenyl)-1-phenyl-3,3a,4,9b-tetrahydro-1H-chromeno[4,3-c]isoxazole-3a-carboxylate [PDF]
Acta Crystallographica Section E, 2011 In the title compound, C27H27NO4, the five-membered isoxazole ring adopts an envelope conformation and the six-membered pyran ring adopts a half-chair conformation.
J. Kanchanadevi +4 more
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1-(3-p-Tolylisoxazol-5-yl)cyclohexanol [PDF]
Acta Crystallographica Section E, 2009 The title compound, C16H19NO2, contains two molecules in the asymmetric unit. Each molecule is composed of three interconnected rings, two essentially planar rings, viz.
Lahcen El Ammari +4 more
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4-(4-Methoxyphenyl)-3-methyl-1,6-dioxa-2,8-diaza-s-indacen-5(7H)-one [PDF]
Acta Crystallographica Section E, 2009 In the molecule of the title compound, C16H12N2O4, the pyridine ring is oriented at the same dihedral angle of 2.92 (3)° with respect to the furan and isoxazole rings, while the dihedral angle between furan and isoxazole rings is 1.34 ...
Shu Yan, Xiao-Hong Zhang, Li-Xin Zhang
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Regulating AMPA Receptors with Isoxazole-4-Carboxamide Derivatives: An Electrophysiological Study [PDF]
Journal of XenobioticsIsoxazole carboxamide derivatives are intriguing modulators of ionotropic glutamate receptors; more specifically, their prospective analgesic activities based on non-opioid pathways have sparked widespread research.
Mohammad Qneibi +6 more
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