Results 11 to 20 of about 17,156 (211)

Molecular modeling, synthesis, and antiproliferative evaluation of new isoxazole ring linked by Schiff bases and azo bond

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2023
Lung cancer is the most common malignancy worldwide, with approximately 1.8 million new cases yearly. Cytotoxic drugs are frequently used in cancer treatment.
Duha E Taha   +2 more
doaj   +1 more source

Isoxazolyl-Derived 1,4-Dihydroazolo[5,1-c][1,2,4]Triazines: Synthesis and Photochemical Properties

open access: yesMolecules, 2023
New fluorescent dyes containing an assembled 1,4-dihydroazolo[5,1-c][1,2,4]triazine (DAT) core and an isoxazole ring were synthesized through a reaction between diazopyrazole or diazoimidazoles and isoxazolyl-derived enamines in mild conditions.
Elena V. Sadchikova   +4 more
doaj   +1 more source

Synthesis and characterization of selected fused isoxazole and pyrazole derivatives and their antimicrobial activity [PDF]

open access: yesJournal of the Serbian Chemical Society, 2009
New potent antibacterials, fused isoxazole and pyrazole derivatives, were synthesized using 5,5-dimethylcyclohexane-1,3-dione (1) and 3-[(4-chlorobenzylidene) amino]-2-thioxoimidazolidin-4-one (2) as synthons.
Dabholkar Vijay V., Ansari Faisal Y.
doaj   +3 more sources

New Approaches for the Synthesis of Heterocyclic Compounds Derived from Cyclohexan-1,3-dione with Anti-proliferative Activities

open access: yesActa Chimica Slovenica, 2021
In the present work a series of heterocyclization reactions were adopted using cyclohexan-1,3-dione through its reaction with either furan-2-carbaldehyde or thiophene-2-carbaldehyde to give the corresponding ylidene derivatives 3a,b. The latter compounds
Rafat Milad Mohareb   +2 more
doaj   +1 more source

(3-Methyl-3a,4,7,7a-tetrahydro-5H-4,7-methanoisoxazolo[4,5-d][1,2]oxazin-5-yl)(phenyl)methanone

open access: yesActa Crystallographica Section E, 2014
The title compound, C14H14N2O3, is the exo isomer with a syn arrangement of two O atoms in the isoxazole and oxazine rings. The dihedral angle between the isoxazole and phenyl rings is 60.38 (4)°.
Alan J. Lough   +2 more
doaj   +1 more source

Synthesis and evaluation of anti-leishmania activity of analogs isoxazoles derivatives of grandisin and veraguensin neolignans

open access: yesOrbital: The Electronic Journal of Chemistry, 2012
Using the concept of bioisosterismo, the new analogs isoxazole were designed from the molecular modification of grandisin and veraguensin neolignans, which have a grouping that is a furan ring bioisóstero isoxazole.
Ozildéia Soares   +5 more
doaj   +1 more source

5,8-Dimethoxy-3,9-dimethyl-3a,4,9,9a-tetrahydro-4,9-epoxynaphtho[2,3-d]isoxazole

open access: yesActa Crystallographica Section E, 2014
The title compound, C15H17NO4, is the exo isomer with a syn arrangement of the O atom in the isoxazole ring to the methyl group of the bicyclic alkene. The dihedral angle between the isoxazole ring and the benzene ring is 7.42 (9)°.
Alan J. Lough   +2 more
doaj   +1 more source

1-Methyl-3-(2-methylphenyl)-3,3a,4,9b-tetrahydro-1H-chromeno[4,3-c][1,2]oxazole-3a-carbonitrile

open access: yesActa Crystallographica Section E, 2011
In the title compound, C19H18N2O2, the five-membered isoxazole ring adopts an envelope conformation and the deviation of the N atom from the mean plane of the isoxazole ring is −0.3256 (11) Å.
K. Swaminathan   +3 more
doaj   +1 more source

Ethyl 5-methyl-3-phenylisoxazole-4-carboxylate

open access: yesActa Crystallographica Section E, 2013
In the title compound, C13H13NO3, the dihedral angle between the phenyl and isoxazole rings is 43.40 (13)°. The ethoxycarbonyl group is rotated out of the plane of the isoxazole ring by 16.2 (13)°.
Chandra   +4 more
doaj   +1 more source

Lewis acid-promoted direct synthesis of isoxazole derivatives

open access: yesBeilstein Journal of Organic Chemistry, 2023
Isoxazole derivatives were synthesized via a one-pot method utilizing 2-methylquinoline derivatives as template substrates, sodium nitrite as a nitrogen-oxygen source, and solely using aluminum trichloride as the additive.
Dengxu Qiu   +3 more
doaj   +1 more source

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