Results 21 to 30 of about 32,281 (298)

Synthesis of Spiro Pyrazolone-Oxindole and Bicyclic Pyrazolone Derivatives via Solvent-Dependent Regioselective Aza-1,4/1,6-Michael and Intramolecular Cycloaddition under Catalyst-Free Conditions

SynOpen, 2021
A solvent-dependent, highly regioselective [3+2]-cyclo­addition reaction of isoxazole-styrenes and azomethine imines under catalyst-free conditions is reported, furnishing a library of pyrazolone–spirooxindole hybrids.
Kota Sathish, Sakkani Nagaraju, Dhurke Kashinath   +2 more
doaj   +1 more source

Co-crystalization and in vitro biological characterization of 5-Aryl-4-(5-substituted-2-4-dihydroxyphenyl)-1,2,3-thiadiazole Hsp90 inhibitors [PDF]

, 2012
A potential therapeutic strategy for targeting cancer that has gained much interest is the inhibition of the ATP binding and ATPase activity of the molecular chaperone Hsp90.
Chrisostomos Prodromou, Daumantas Matulis, Egidijus Kazlauskas, Inga Čikotienė, Paul Workman, S. Mark Roe, Swee Y. Sharp, Wenqing Xu   +7 more
core   +5 more sources

Effect of building block transformation in covalent triazine‐based frameworks for enhanced CO2 uptake and metal‐free heterogeneous catalysis [PDF]

, 2020
Invited for the cover of this issue is the group of Pascal Van Der Voort at the University of Ghent and colleagues at Technische Universitat Berlin. The image depicts the covalent triazine frameworks reported in the manuscript for the sorption of CO2 and
Jena, Himanshu, Krishnaraj, Chidharth, Leus, Karen, Schmidt, Johannes, Van Der Voort, Pascal, Van Hecke, Kristof   +5 more
core   +2 more sources

Über Triaryl‐isoxazole [PDF]

Berichte der deutschen chemischen Gesellschaft (A and B Series), 1921
n ...
Meisenheimer, Jakob, Weibezahn, Karl
openaire   +3 more sources

Synthesis and Biological Evaluation of Novel Isoxazole-Amide Analogues as Anticancer and Antioxidant Agents

BioMed Research International, 2021
Cancer now is one of the leading causes of mortality in the world. There has been a lot of effort to discover new anticarcinogenic agents that allow treatment with fewer side effects. A series of isoxazole-carboxamide derivatives (2a–2g) were synthesised
A. Eid, Mohammed Hawash, J. Amer, Abdullah Jarrar, Samira Qadri, Iman Alnimer, Aya Sharaf, Raya Zalmoot, Osama Hammoudie, S. Hameedi, A. Mousa   +10 more
semanticscholar   +1 more source

Synthesis of novel indole-isoxazole hybrids and evaluation of their cytotoxic activities on hepatocellular carcinoma cell lines

BMC Chemistry, 2021
Background Liver cancer is predicted to be the sixth most diagnosed cancer globally and fourth leading cause of cancer deaths. In this study, a series of indole-3-isoxazole-5-carboxamide derivatives were designed, synthesized, and evaluated for their ...
Mohammed Hawash, D. Kahraman, S. Ergun, R. Cetin-Atalay, S. Baytas   +4 more
semanticscholar   +1 more source

Lewis acid-promoted direct synthesis of isoxazole derivatives

Beilstein Journal of Organic Chemistry, 2023
Isoxazole derivatives were synthesized via a one-pot method utilizing 2-methylquinoline derivatives as template substrates, sodium nitrite as a nitrogen-oxygen source, and solely using aluminum trichloride as the additive.
Dengxu Qiu, Chenhui Jiang, Pan Gao, Yu Yuan   +3 more
doaj   +1 more source

New Approaches for the Synthesis of Heterocyclic Compounds Derived from Cyclohexan-1,3-dione with Anti-proliferative Activities

Acta Chimica Slovenica, 2021
In the present work a series of heterocyclization reactions were adopted using cyclohexan-1,3-dione through its reaction with either furan-2-carbaldehyde or thiophene-2-carbaldehyde to give the corresponding ylidene derivatives 3a,b. The latter compounds
Rafat Milad Mohareb, Yara Raafat Milad, Ayat Ali Masoud   +2 more
doaj   +1 more source

Büchwald-Hartwig reaction applied to synthesis of new luminescent liquid crystal triarylamines derived from isoxazoles [PDF]

, 2015
© 2015 Taylor & Francis Group, LLC. The present work describes the synthesis and characterization of novel series of triarylamines isoxazoles (TAA) addressed to the organic photovoltaic materials. Diarylisoxazoles were synthesized by sequential [3+2] 1,
Fernandes, T. H. M., Kelly, S. M., Merlo, A. A., Vilela, G. D.   +3 more
core   +2 more sources

Antimicrobial, Antioxidant, and Anticancer Activities of Some Novel Isoxazole Ring Containing Chalcone and Dihydropyrazole Derivatives

Molecules, 2020
Our previous work identified isoxazole-based chalcones and their dihydropyrazole derivatives as two important five-membered heterocycles having antitubercular activity.
A. Shaik, Richie R. Bhandare, Kishor Palleapati, Srinath Nissankararao, V. Kancharlapalli, Shahanaaz Shaik   +5 more
semanticscholar   +1 more source