Results 41 to 50 of about 17,156 (211)
4-(4-Fluorophenyl)-2-methyl-3-(1-oxy-4-pyridyl)isoxazol-5(2H)-one
Acta Crystallographica Section E, 2008 The crystal structure of the title compound, C15H11FN2O3, was determined as part of a study on the biological activity of isoxazolone derivatives as p38 mitogen-activated protein kinase (MAPK) inhibitors.
Stefan Laufer +2 more
doaj +1 more source
WONOEP XVII appraisal: The immunopathogenesis of epilepsy
Epilepsia, EarlyView.Abstract There is a wealth of data indicating that the immune system plays an important role in seizure disorders. This includes autoimmune encephalitis, in which an immune response directed against neuronal antigens results in brain inflammation and subsequent seizure activity, as well as autoimmune‐associated epilepsy and neuroinflammatory changes ...
Nihan Çarçak +12 more
wiley +1 more source
SYNTHESIS OF UNSYMMETRICALLY SUBSTITUTED ISOXAZOLES AS INTERMEDIATES FOR BENT-CORE MESOGENS
Studia Universitatis Babes-Bolyai Chemia, 2016 3,5-Disubstituted isoxazoles have been designed and synthesized to be used as central units for bent-core mesogens. The substituents at position 3 of the isoxazole ring are either hydroxymethyl or carboxyl, while alkenyl-terminated substituents have ...
Gheorghe ROMAN
doaj
4-(4-Chlorophenyl)-5-phenylisoxazole
Acta Crystallographica Section E, 2009 The title compound, C15H10ClNO, is a functionalized isoxazole with a chlorophenyl and a phenyl substitutent. The mean plane of the isoxazole ring is inclined to those of the two benzene ring mean planes by 38.32 (16) and 43.91 (18 ...
M. Krishnaiah +3 more
doaj +1 more source
Magnetic Resonance in Chemistry, Volume 64, Issue 3, Page 324-332, March 2026.We report the results from a kinetic and mechanistic investigation of an inverse‐electron‐demand Diels–Alder (IEDDA) cycloaddition involving an oxazole‐type diene synthesized via an Ugi–Zhu multicomponent reaction (UZ‐3CR). ABSTRACT Pyridines are a crucial class of heterocycles with widespread applications in natural products, pharmaceuticals, and ...
Galdina V. Suárez‐Moreno +6 more
wiley +1 more source
3-Benzyl-5-methyl-1,2-benzoxazole 2-oxide
Acta Crystallographica Section E, 2012 In the title compound, C15H13NO2, the isoxazole unit and the attached benzene ring are almost coplanar, making a dihedral angle of 1.42 (8)°.
G. Anuradha +3 more
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Acta Crystallographica Section E: Crystallographic Communications, 2021 The title compound, C9H7NO2S crystallizes with two independent molecules (A and B) in the asymmetric unit with Z = 8. Both molecules are almost planar with a dihedral angle between the isoxazole and thiophen rings of 3.67 (2)° in molecule A and 10.00 (1)
Rima Laroum +5 more
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1-(3-p-Tolylisoxazol-5-yl)cyclohexanol
Acta Crystallographica Section E, 2009 The title compound, C16H19NO2, contains two molecules in the asymmetric unit. Each molecule is composed of three interconnected rings, two essentially planar rings, viz.
Lahcen El Ammari +4 more
doaj +1 more source
Acta Crystallographica Section E, 2011 In the title compound, C27H27NO4, the five-membered isoxazole ring adopts an envelope conformation and the six-membered pyran ring adopts a half-chair conformation.
J. Kanchanadevi +4 more
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Development of a Copper‐Free Click Reaction for Asymmetric Rh Diene Catalysis Under Confinement
Advanced Synthesis &Catalysis, Volume 368, Issue 1, January 2026.A copper‐free amino–yne click reaction enables the selective functionalization of chiral diene ligands with both soluble and immobilized amines. Substituent‐controlled stereoselectivity affords (E)‐ and (Z)‐enaminone ligands, which are converted into Rh complexes for asymmetric catalysis under homogeneous and heterogeneous conditions.
Manuel Kirchhof +10 more
wiley +1 more source