Results 51 to 60 of about 32,281 (298)

Platelet protective efficacy of 3,4,5 trisubstituted isoxazole analogue by inhibiting ROS-mediated apoptosis and platelet aggregation [PDF]

open access: yes, 2016
Thrombocytopenia is a major hematological concern in oxidative stress-associated pathologies and chronic clinical disorders, where premature platelet destruction severely affects the normal functioning of thrombosis and hemostasis.
Basappa, .   +9 more
core   +1 more source

Efficient Nickel Precatalysts for Suzuki‐Miyaura Cross‐Coupling of Aryl Chlorides and Arylboronic Acids Under Mild Conditions

open access: yesAngewandte Chemie, EarlyView.
The synthesis and catalytic properties of Ni(II) complexes, with the general formula Ni(NHC)[P(OR)3](Ar)Cl, are described. These air‐stable complexes are effective under mild conditions and low catalytic loading for the Suzuki‐Miyaura cross‐coupling for a range of electronically and sterically differentiated coupling partners.
Morgan E. John   +9 more
wiley   +2 more sources

Synthesis of Some Novel Heterocyclic and Schiff Base Derivatives as Antimicrobial Agents

open access: yesMolecules, 2015
Treatment of 2,3-diaryloxirane-2,3-dicarbonitriles 1a–c with different nitrogen nucleophiles, e.g., hydrazine, methyl hydrazine, phenyl hydrazine, hydroxylamine, thiosemicarbazide, and/or 2-amino-5-phenyl-1,3,4-thiadiazole, afforded pyrazole, isoxazole ...
Mohamed E. Azab   +2 more
doaj   +1 more source

Symmetric 3,5-Pyrazole and Isoxazole Heterocycles Comprising a Bent Core Unit: Synthesis and Mesomorphic Characterisation [PDF]

open access: yes, 2015
The synthesis and characterisation of some new liquid crystalline (LC) heteroaromatic compounds containing the five-membered pyrazole/isoxazole rings is reported. Some of the compounds exhibited enantiotropic LC properties.
Hariprasad, S., Srinivasa, H.T.
core   +1 more source

5-(Benzoyloxymethyl)isoxazole-3-carboxylic Acid Ethyl Ester

open access: yesMolbank
We describe here the palladium hydrogenation of ethyl 5-(benzoyloxymethyl)isoxazole-3-carboxylate. The presence of two reducible sites in the molecule, namely the benzylic-like position and the isoxazole N–O bond, creates a possible competition.
Cosimo Antonini   +2 more
doaj   +1 more source

5-[5-(4-Chlorophenyl)isoxazol-3-yl]-N-phenyl-1,3,4-oxadiazol-2-amine

open access: yesIUCrData, 2019
The title compound, C17H11ClN4O2, consists of chlorophenyl (A), isoxazolyl (B), oxadiazolyl (C) and phenyl (D) rings with twist angles between the planes through neighbouring rings A/B, B/C and C/D of 14.9 (1), 1.8 (1) and 8.9 (1)° respectively.
Gamal A. El-Hiti   +5 more
doaj   +1 more source

Ring-Opening Fluorination of Isoxazoles

open access: yesOrganic Letters, 2022
A ring-opening fluorination of isoxazoles has been developed. By treating isoxazoles with an electrophilic fluorinating agent (Selectfluor®), fluorination followed by deprotonation leads to tertiary fluorinated carbonyl compounds. The present method features mild reaction conditions, good functional group tolerance, and simple experimental procedure ...
Masaaki Komatsuda   +4 more
openaire   +2 more sources

Time-Resolved Photoelectron Spectroscopy Studies of Isoxazole and Oxazole

open access: yesJournal of Physical Chemistry A, 2020
The excited state relaxation pathways of isoxazole and oxazole upon excitation with UV-light were investigated by nonadiabatic ab initio dynamics simulations and time-resolved photoelectron spectroscopy.
T. Geng   +6 more
semanticscholar   +1 more source

The synthetic and therapeutic expedition of isoxazole and its analogs

open access: yesMedicinal Chemistry Research, 2018
Isoxazole, constituting an important family of five-membered heterocycles with one oxygen atom and one nitrogen atom at adjacent positions is of immense importance because of its wide spectrum of biological activities and therapeutic potential.
N. Agrawal, P. Mishra
semanticscholar   +1 more source

Structural study and Hirshfeld surface analysis of (Z)-4-(2-methoxybenzylidene)-3-phenylisoxazol-5(4H)-one

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2021
The title compound, C17H13NO3, adopts a Z configuration about the C=C bond. The isoxazole and methoxybenzylidene rings are almost coplanar with a dihedral angle of 9.63 (7)° between them.
Assia Benouatas   +5 more
doaj   +1 more source

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