Results 51 to 60 of about 32,281 (298)
Platelet protective efficacy of 3,4,5 trisubstituted isoxazole analogue by inhibiting ROS-mediated apoptosis and platelet aggregation [PDF]
Thrombocytopenia is a major hematological concern in oxidative stress-associated pathologies and chronic clinical disorders, where premature platelet destruction severely affects the normal functioning of thrombosis and hemostasis.
Basappa, .+9 more
core +1 more source
The synthesis and catalytic properties of Ni(II) complexes, with the general formula Ni(NHC)[P(OR)3](Ar)Cl, are described. These air‐stable complexes are effective under mild conditions and low catalytic loading for the Suzuki‐Miyaura cross‐coupling for a range of electronically and sterically differentiated coupling partners.
Morgan E. John+9 more
wiley +2 more sources
Synthesis of Some Novel Heterocyclic and Schiff Base Derivatives as Antimicrobial Agents
Treatment of 2,3-diaryloxirane-2,3-dicarbonitriles 1a–c with different nitrogen nucleophiles, e.g., hydrazine, methyl hydrazine, phenyl hydrazine, hydroxylamine, thiosemicarbazide, and/or 2-amino-5-phenyl-1,3,4-thiadiazole, afforded pyrazole, isoxazole ...
Mohamed E. Azab+2 more
doaj +1 more source
Symmetric 3,5-Pyrazole and Isoxazole Heterocycles Comprising a Bent Core Unit: Synthesis and Mesomorphic Characterisation [PDF]
The synthesis and characterisation of some new liquid crystalline (LC) heteroaromatic compounds containing the five-membered pyrazole/isoxazole rings is reported. Some of the compounds exhibited enantiotropic LC properties.
Hariprasad, S., Srinivasa, H.T.
core +1 more source
5-(Benzoyloxymethyl)isoxazole-3-carboxylic Acid Ethyl Ester
We describe here the palladium hydrogenation of ethyl 5-(benzoyloxymethyl)isoxazole-3-carboxylate. The presence of two reducible sites in the molecule, namely the benzylic-like position and the isoxazole N–O bond, creates a possible competition.
Cosimo Antonini+2 more
doaj +1 more source
5-[5-(4-Chlorophenyl)isoxazol-3-yl]-N-phenyl-1,3,4-oxadiazol-2-amine
The title compound, C17H11ClN4O2, consists of chlorophenyl (A), isoxazolyl (B), oxadiazolyl (C) and phenyl (D) rings with twist angles between the planes through neighbouring rings A/B, B/C and C/D of 14.9 (1), 1.8 (1) and 8.9 (1)° respectively.
Gamal A. El-Hiti+5 more
doaj +1 more source
Ring-Opening Fluorination of Isoxazoles
A ring-opening fluorination of isoxazoles has been developed. By treating isoxazoles with an electrophilic fluorinating agent (Selectfluor®), fluorination followed by deprotonation leads to tertiary fluorinated carbonyl compounds. The present method features mild reaction conditions, good functional group tolerance, and simple experimental procedure ...
Masaaki Komatsuda+4 more
openaire +2 more sources
Time-Resolved Photoelectron Spectroscopy Studies of Isoxazole and Oxazole
The excited state relaxation pathways of isoxazole and oxazole upon excitation with UV-light were investigated by nonadiabatic ab initio dynamics simulations and time-resolved photoelectron spectroscopy.
T. Geng+6 more
semanticscholar +1 more source
The synthetic and therapeutic expedition of isoxazole and its analogs
Isoxazole, constituting an important family of five-membered heterocycles with one oxygen atom and one nitrogen atom at adjacent positions is of immense importance because of its wide spectrum of biological activities and therapeutic potential.
N. Agrawal, P. Mishra
semanticscholar +1 more source
The title compound, C17H13NO3, adopts a Z configuration about the C=C bond. The isoxazole and methoxybenzylidene rings are almost coplanar with a dihedral angle of 9.63 (7)° between them.
Assia Benouatas+5 more
doaj +1 more source