A novel and efficient approach for the synthesis of functionalized isoxazoles via palladium-catalyzed cascade annulation/allylation of alkynyl oxime ethers with allyl halides has been established.
Can Li +4 more
semanticscholar +1 more source
Synthesis of N-Fmoc-ProtectedAmino Alkyl Thiocyanates/Selenocyanates and their Applicationin the Preparation of 5-Substituted S/Se-Linked Tetrazoles [PDF]
A novel class of N-Fmoc-protected amino alkyl thiocy- anates/selenocyanates has been prepared by thiocyanation/seleno-cyanation of the corresponding alkyl iodides. These thiocyanates/selenocyanates undergo a facile [2+3]-cycloaddition reaction
Basavalingappa, P. Vasantha +2 more
core +1 more source
Effects of Isoxazolyl Steroids on Key Genes of Sonic Hedgehog Cascade Expression in Tumor Cells
Activation of the Hedgehog (Hh) signaling pathway is often associated with the progression of various types of cancer. The purpose of study was to search for inhibitors of the Hh signaling pathway among eight compounds belonging to the group of ...
Anna Aleksandrova +10 more
doaj +1 more source
Estudio del efecto antiagregante plaquetario de isozaxoles [PDF]
49 p.Introducción. Las enfermedades cardiovasculares (ECV) representan la principal causa de muerte en el mundo. Las plaquetas cumplen un rol fundamental en la fisiopatología de las ECV, por lo que buscar nuevas formas de inhibición plaquetaria podría ...
Palomo González, Iván (Prof. Guía) +1 more
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Increased Insertion of Glutamate Receptor 2-Lacking α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid (AMPA) Receptors at Hippocampal Synapses upon Repeated Morphine Administration [PDF]
Sophie K. Billa +6 more
openalex +1 more source
Microwave induced synthesis of some fused thiazoloquinazoline derivatives under solvent free conditions using LiBr as a catalyst [PDF]
Two rapid and efficient methods for the preparation off used thiazoloquinazoline derivatives by the reaction of chalcones with hydroxylamine, urea and hydrazine hydrate under solvent free condition and microwave exposure are reported.
Ameta, Chetna +4 more
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Electrochemical Synthesis of New Isoxazoles and Triazoles Tethered with Thiouracil Base as Inhibitors of Histone Deacetylases in Human Breast Cancer Cells [PDF]
Divakar Vishwanath +9 more
openalex +1 more source
Palladium-catalyzed 2,5-diheteroarylation of 2,5-dibromothiophene derivatives
Conditions allowing the one pot 2,5-diheteroarylation of 2,5-dibromothiophene derivatives in the presence of palladium catalysts are reported.
Fatma Belkessam +4 more
doaj +1 more source
Synthesis of some isoxazoline, isoxazole and pyrazole carboxylic acids as the precursors of new 1,2-diacyl-1-alkylhydrazines [PDF]
A number of isoxazoline, isoxazole and pyrazole carboxylic acids or their esters has been synthesized via the 1,3-dipolar cycloaddition of corresponding nitrile oxides or diazomethane to unsaturated dipolarophiles.
Antonevich, I. P., Katok, Ya. M.
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