Results 111 to 120 of about 19,238 (306)
Developmental Medicine &Child Neurology, Volume 67, Issue 5, Page 591-599, May 2025.Hypoxic‐ischemic encephalopathy (HIE) is a neurologic condition that is caused by insufficient oxygen and blood flow to a newborn infant’s brain. Although therapeutic hypothermia can reduce the degree of brain injury in some infants with HIE, many infants with HIE will have significant lifelong disabilities despite receiving this treatment.
Natalie H. Chan +5 more
wiley +1 more source
Semina: Ciências Agrárias, 2010 Herbicide selectivity is the basis for successfull weed chemical control in agricultural production, as it is considered as a measurement of the difeerential response of different plant species to a certain herbicide.
Rosecler Salete Canossa +6 more
doaj +1 more source
New routes towards reutericyclin analogues [PDF]
, 2013 A range of N-acylpyrrolo[3,4-c]isoxazoles and derived N-5 acyltetramides has been prepared via a nitrile oxide dipolar cycloaddition approach, as analogues of the acyltetramic acid metabolite reutericyclin, of interest for their antibiotic potential ...
Ching-Man (Carole) Law (7165019) +3 more
core +1 more source
Substituent effects in isoxazoles: identification of 4-substituted isoxazoles as Michael acceptors
Journal of the Chemical Society, Perkin Transactions 2, 2002 Crystallographic and theoretical studies have been used to investigate substituent effects, which are manifest in electrochemical and yeast-catalysed reactions of 4- and 5-acyl-, alkoxycarbonyl-, cyano- and phenyl-substituted isoxazoles. The results show that isoxazoles substituted at the 4-position with π-electron-withdrawing substituents have ...
Lee, Connie +6 more
openaire +2 more sources
Química Nova, 2010 The synthesis and reactivity of α-oxoketenes dithioacetals (S,S-acetals), general structure [(R¹C=OC(R²)=C(SR³)(SR4)], are reported. We also showed the application of S,S acetals as synthons for efficient synthesis of isoxazoles, pyrazoles ...
Geonir M. Siqueira +5 more
doaj +1 more source
CXX.—Action of alkalis on the nitro-compounds of the paraffin series. Part II. Reactions and constitution of methazonic acid and the mode of formation of isoxazoles [PDF]
, 1900 Wyndham R. Dunstan, Ernest Goulding
openalex +1 more source
Synthetic isoxazole as antiplatelet agent
Platelets, 2013 Abstract Nine synthetic isoxazoles were evaluated as antiplatelet agents and studied the possible mechanism of more active compound. The initial screening was evaluating all compounds against platelet aggregation assays. The most active compound was isoxazole 8 showing an inhibition of platelet aggregation around 70%. In subsequent experiments, ADP and
Gutierrez, Margarita +4 more
openaire +5 more sources
Organic Letters, 2018 A novel iminoxyl radical-promoted dichotomous regioselective 5-exo-trig cyclization onto vinylic halogen/1,2-halogen radical shift sequence is developed for the synthesis of halomethyl isoxazoles/cyclic nitrones using β-halo-β,γ- and γ-halo-γ,δ ...
Hong-Lei Chen +5 more
semanticscholar +1 more source
SynOpen, 2018 Reaction of enantiopure 3,4-dialkoxy-pyrroline N-oxides with benzyne affords the expected tetrahydrobenzo[d]pyrrolo[1,2-b]isoxazoles along with an unexpected 2,3-disubstitued-N-phenyl-pyrrole derived from an unprecedented rearrangement of the adduct of ...
Franca M. Cordero +3 more
doaj +1 more source