Results 111 to 120 of about 20,504 (258)

Synthesis and Biological Evaluation of Some New Pyridines, Isoxazoles and Isoxazolopyridazines Bearing 1,2,3-Triazole Moiety

open access: yesActa Poloniae Pharmaceutica - Drug Research, 2019
: Some new isoxazole derivatives 3a-d were synthesized via the reaction of 3-(dimethylamino)-1-(5- methyl-1-(3-nitrophenyl)-1 H -1,2,3-triazol-4-yl)prop-2-en-1-one ( 1 ) with different hydroximoyl chloride derivatives 2a-d .
Anhar Hassan   +3 more
semanticscholar   +1 more source

Estudio del efecto antiagregante plaquetario de isozaxoles [PDF]

open access: yes, 2008
49 p.Introducción. Las enfermedades cardiovasculares (ECV) representan la principal causa de muerte en el mundo. Las plaquetas cumplen un rol fundamental en la fisiopatología de las ECV, por lo que buscar nuevas formas de inhibición plaquetaria podría ...
Palomo González, Iván (Prof. Guía)   +1 more
core  

Effects of Isoxazolyl Steroids on Key Genes of Sonic Hedgehog Cascade Expression in Tumor Cells

open access: yesMolecules
Activation of the Hedgehog (Hh) signaling pathway is often associated with the progression of various types of cancer. The purpose of study was to search for inhibitors of the Hh signaling pathway among eight compounds belonging to the group of ...
Anna Aleksandrova   +10 more
doaj   +1 more source

Microwave induced synthesis of some fused thiazoloquinazoline derivatives under solvent free conditions using LiBr as a catalyst [PDF]

open access: yes
Two rapid and efficient methods for the preparation off used thiazoloquinazoline derivatives by the reaction of chalcones with hydroxylamine, urea and hydrazine hydrate under solvent free condition and microwave exposure are reported.
Ameta, Chetna   +4 more
core  

Synthesis of the omega-brominated alpha-trifluoroacetylcycloalkanones and their isoxazole derivatives

open access: yesJournal of the Brazilian Chemical Society, 2006
The reactions of a serie of the 2-trifluoroacetyl-1-methoxy-1-cycloalkenes (1a-1e) and 2-trifluoroacetylcycloalkanones (2a-2e) with molecular bromine to obtain omega-bromo-alpha-trifluoroacetylcycloalkanones (3a-3e, 4a) is reported. Was determined that 2-
Flores Alex F. C.   +5 more
doaj  

Palladium-catalyzed 2,5-diheteroarylation of 2,5-dibromothiophene derivatives

open access: yesBeilstein Journal of Organic Chemistry, 2014
Conditions allowing the one pot 2,5-diheteroarylation of 2,5-dibromothiophene derivatives in the presence of palladium catalysts are reported.
Fatma Belkessam   +4 more
doaj   +1 more source

An Overview of Biological and Synthetic Aspects of Thiazole Derivatives in Heterocyclic Chemistry [PDF]

open access: yes, 2016
These overviews signify a study covering the literature on thiazole derivatives in heterocyclic chemistry. This brief analysis as well provides a revise on current reports and demonstrates the utility and the effectiveness of this approach.
Jain, N. (Nidhi), Singh, B. (Bhawani)
core  

Direct ring fluorination of 3-substituted 5-(1,3-dioxane) acetal isoxazoles: application to the formal synthesis of a bioactive fluorinated isoxazole

open access: yesComptes Rendus. Chimie
The access to a novel variety of 4-fluorinated isoxazoles bearing an aryl or alkyl group at the C-3 position and an acetal fragment at the C-5 position has been achieved through a direct fluorination using N-fluorobenzenesulfonimide (NFSI) with yields up
Bacheley, Lucas   +3 more
doaj   +1 more source

Synthesis and Physiological Activity of 3-Hydroxyphenyl 5-Aryl Isoxazoles [PDF]

open access: green, 1973
A. KRISHNA MURTHY   +2 more
openalex   +1 more source

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