Results 11 to 20 of about 19,561 (308)
Molecules, 2021 Diabetes mellitus is a major health problem globally. The management of carbohydrate digestion provides an alternative treatment. Flavonoids constitute the largest group of polyphenolic compounds, produced by plants widely consumed as food and/or used ...
Faisal K. Algethami +6 more
doaj +2 more sources
Ring-Opening Fluorination of Isoxazoles
Organic Letters, 2022 A ring-opening fluorination of isoxazoles has been developed. By treating isoxazoles with an electrophilic fluorinating agent (Selectfluor®), fluorination followed by deprotonation leads to tertiary fluorinated carbonyl compounds. The present method features mild reaction conditions, good functional group tolerance, and simple experimental procedure ...
Masaaki Komatsuda +4 more
openaire +3 more sources
ISOXAZOLE – A POTENT PHARMACOPHORE [PDF]
International Journal of Pharmacy and Pharmaceutical Sciences, 2017 Isoxazole is an azole with an oxygen atom next to the nitrogen. Isoxazole rings are found in some natural products, such as ibotenic acid and also found in a number of drugs, including COX-2 inhibitor valdecoxib. Furoxan, a nitric oxide donor is containing isoxazolyl group & found in many β-lactamase resistant antibiotics, such as cloxacillin ...
S. Raja, Krishna Veni Chikkula
openaire +5 more sources
Gold-Catalyzed Cyclization of Yndiamides with Isoxazoles via α-Imino Gold Fischer Carbenes. [PDF]
Chemistry, 2023 Gold catalysis is an important method for alkyne functionalization. Here we report the gold-catalyzed formal [3+2] aminative cyclization of yndiamides and isoxazoles in a direct synthesis of polysubstituted diaminopyrroles, which are important motifs in ...
Tong Z +4 more
europepmc +3 more sources
A Facile Approach to Bis(isoxazoles), Promising Ligands of the AMPA Receptor
Molecules, 2021 A convenient synthetic approach to novel functionalized bis(isoxazoles), the promising bivalent ligands of the AMPA receptor, was elaborated.
D. Vasilenko +11 more
semanticscholar +1 more source
Synthesis and Antiprotozoal Profile of 3,4,5‐Trisubstituted Isoxazoles
ChemistryOpen, 2021 A series of 60 4‐aminomethyl 5‐aryl‐3‐substituted isoxazoles were synthesized by an efficient method and evaluated in vitro against Leishmania amazonensis and Trypanosoma cruzi, protozoa that cause the neglected tropical diseases leishmaniasis and Chagas
Prof. Fernanda Andreia Rosa +9 more
doaj +1 more source
Green Chemistry Letters and Reviews, 2022 A convenient and efficient [3 + 2] cycloaddition reaction of alkenes and alkynes with the in situ generated nitrile oxides from aldoximes in the presence of NaCl, Oxone and Na2CO3 has been developed to afford a series of isoxazoles and isoxazolines at ...
Run-Kai Fang +3 more
doaj +1 more source
Büchwald-Hartwig reaction applied to synthesis of new luminescent liquid crystal triarylamines derived from isoxazoles [PDF]
, 2015 © 2015 Taylor & Francis Group, LLC. The present work describes the synthesis and characterization of novel series of triarylamines isoxazoles (TAA) addressed to the organic photovoltaic materials. Diarylisoxazoles were synthesized by sequential [3+2] 1,
Fernandes, T. H. M. +3 more
core +2 more sources
Facile synthesis of isoxazoles and pyrazoles from ß-diketohydrazones [PDF]
, 2009 Indexación: ScieloNew 3,5-dimethyl-4-[(E)-4-(R1-phenyl)diazenyl]isoxazoles and 3,5-dimethyl-1-(R2-phenyl)-4-[(E)-(R1-phenyl)diazenyl]-1H-pyrazoles may be obtained by reaction of 3-[2-(R1-phenyl)hydrazono)]pentane-2,4-dione with H2NOH-HCl and R2-4-C6H4 ...
Bustos, Carlos +4 more
core +1 more source
Synthesis of 3,5-Disubstituted Isoxazoles and Isoxazolines in Deep Eutectic Solvents [PDF]
, 2015 The synthesis of different 3,5-disubstituted isoxazoles and related isoxazolines using choline chloride:urea as deep eutectic solvent (DES) in a one-pot three step reaction has been accomplished successfully. The use of highly nucleophilic functionalized
Pérez Galera, Juana María +1 more
core +3 more sources