Results 11 to 20 of about 19,238 (306)

A Facile Approach to Bis(isoxazoles), Promising Ligands of the AMPA Receptor

open access: yesMolecules, 2021
A convenient synthetic approach to novel functionalized bis(isoxazoles), the promising bivalent ligands of the AMPA receptor, was elaborated.
D. Vasilenko   +11 more
semanticscholar   +1 more source

Design, Synthesis, and Biological Assessment of Novel Vanillin-Isoxazole Derivatives as Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptor

open access: yesChemistry Proceedings, 2023
The homomeric α7 nicotinic acetylcholine receptor (α7 nAChR) is a cation-permeable pentameric ligand-gated channel present in the nervous system and non-neuronal cells.
Santiago Stabile   +3 more
doaj   +1 more source

Gold(I)-catalyzed synthesis of 3-sulfenyl pyrroles and indoles by a regioselective annulation of alkynyl thioethers [PDF]

open access: yes, 2021
[Image: see text] The combination of nucleophilic nitrenoids and π-acid catalysis has emerged as a powerful tool in heterocycle synthesis. Accessing more varied heterocycle-substitution patterns by maintaining the same reaction pathways across different ...
Davies, Paul   +3 more
core   +1 more source

Self Cycloaddition of o‐Naphthoquinone Nitrosomethide to (±) Spiro{naphthalene(naphthopyranofurazan)}‐one Oxide: An Insight into its Formation

open access: yesChemPlusChem, Volume 87, Issue 12, December 2022., 2022
2‐Hydroxy‐1‐naphthaldehyde oxime was oxidized by a D−A type self cycloaddition to spiro compound. Free reaction energy is calculated at −82.0 kcal/mol indicating its predominance over the intramolecular cyclization of −37.6 kcal/mol. 8‐methoxy substituted oxime is sterically guided to 9‐methoxynaphtho[1,2‐d] instead of spiro adduct resulting to the ...
Demeter Tzeli   +4 more
wiley   +1 more source

Über Triaryl‐isoxazole [PDF]

open access: yesBerichte der deutschen chemischen Gesellschaft (A and B Series), 1921
n ...
Meisenheimer, Jakob, Weibezahn, Karl
openaire   +3 more sources

MnVI-NP–Catalyzed Generation of Nitrile Oxides: Easy Access to Isoxazolines and Isoxazoles via Stereoselective 1,3-Dipolar Cyclo­addition Reactions

open access: yesSynOpen, 2022
The versatility and effectiveness of MnVI-NPs as a catalyst is examined for the generation of nitrile oxides from aldoximes and subsequent 1,3-dipolar cycloaddition reactions.
Yasmin Saima, Saikat Khamarui
doaj   +1 more source

Why Woodward and Hoffmann? And Why 1965?**

open access: yesThe Chemical Record, Volume 23, Issue 1, January 2023., 2023
R. B. Woodward and Roald Hoffmann provided perfect intellectual and experiential synergy for their collaboration on orbital symmetry control of pericyclic reactions. This publication describes their idiosyncratic qualities and how perfectly they matched, at the right place and at the right time.
Jeffrey I. Seeman
wiley   +1 more source

Synthesis and Antiprotozoal Profile of 3,4,5‐Trisubstituted Isoxazoles

open access: yesChemistryOpen, 2021
A series of 60 4‐aminomethyl 5‐aryl‐3‐substituted isoxazoles were synthesized by an efficient method and evaluated in vitro against Leishmania amazonensis and Trypanosoma cruzi, protozoa that cause the neglected tropical diseases leishmaniasis and Chagas
Prof. Fernanda Andreia Rosa   +9 more
doaj   +1 more source

Büchwald-Hartwig reaction applied to synthesis of new luminescent liquid crystal triarylamines derived from isoxazoles [PDF]

open access: yes, 2015
© 2015 Taylor & Francis Group, LLC. The present work describes the synthesis and characterization of novel series of triarylamines isoxazoles (TAA) addressed to the organic photovoltaic materials. Diarylisoxazoles were synthesized by sequential [3+2] 1,
Fernandes, T. H. M.   +3 more
core   +2 more sources

Exploiting the molecular diversity of the synapse to investigate neuronal communication: A guide through the current toolkit

open access: yesEuropean Journal of Neuroscience, Volume 56, Issue 12, Page 6141-6161, December 2022., 2022
Chemical synapses are tiny and overcrowded environments enriched with thousands of protein species. Many efforts have been devoted to developing sensors and actuators able to evaluate and control synaptic communication. Most of these recent tools are based on the engineering of one or more specific synaptic proteins used to target active moieties to ...
Jacopo Lamanna   +3 more
wiley   +1 more source

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