3,5-Bisdimethylamino-isoxazoles II are obtained easily from 1,3-dichloro-trimethinecyanine I and a water solution of hydroxylamine. Besides precedented photo-isomerization of 4-substituted isoxazoles IIb,c to azirines IIIb,c near quantitative thermal ...
G.J. de Voghel+3 more
doaj +1 more source
Chalcones as versatile synthons for the synthesis of 5- and 6-membered nitrogen heterocylces [PDF]
Chalcones belong to the flavonoid family which constitutes one of the major classes of naturally occurring oxygen heterocyclic compounds. The alpha,beta-unsaturated carbonyl system of chalcones possesses two electrophilic reactive centers allowing them ...
Albuquerque, Hélio+3 more
core +1 more source
Copper Nanoparticles on Montmorillonite K-10: A Versatile Catalyst for the One-Pot Synthesis of 3,5-Disubstituted Isoxazoles Using Various Methodologies [PDF]
A readily prepared and versatile heterogeneous catalyst composed of copper nanoparticles supported on montmorillonite MK-10 (CuNPs/MK10) has proven to be highly effective in catalyzing the synthesis of isoxazoles through various one-pot methodologies ...
Bjerg, Esteban Eloy+2 more
core +1 more source
A continuous flow process is presented that directly converts isoxazoles into their oxazole counterparts via a photochemical transposition reaction.
Cormac Bracken, M. Baumann
semanticscholar +1 more source
Co-ingestion of amatoxins and isoxazoles-containing mushrooms and successful treatment: A case report [PDF]
Mushroom poisonings occur when ingestion of wild mushrooms containing toxins takes place, placing the consumers at life-threatening risk. In the present case report, an unusual multiple poisoning with isoxazoles- and amatoxins-containing mushrooms in a ...
Andrade, Sérgio+10 more
core +1 more source
Symmetric 3,5-Pyrazole and Isoxazole Heterocycles Comprising a Bent Core Unit: Synthesis and Mesomorphic Characterisation [PDF]
The synthesis and characterisation of some new liquid crystalline (LC) heteroaromatic compounds containing the five-membered pyrazole/isoxazole rings is reported. Some of the compounds exhibited enantiotropic LC properties.
Hariprasad, S., Srinivasa, H.T.
core +1 more source
Development of Simplified Heterocyclic Acetogenin Analogues as Potent and Selective Trypanosoma brucei Inhibitors [PDF]
This work was funded by the Leverhulme Trust (GJF), and the Wellcome Trust (TKS, WT 093228).Neglected tropical diseases caused by parasitic infections are an on-going and increasing concern and burden to human and animal health, having the most ...
Alali+28 more
core +2 more sources
One-step synthesis of differently bis-functionalized isoxazoles by cycloaddition of carbamoylnitrile oxide with β-keto esters [PDF]
A new protocol for synthesizing different functionalized isoxazoles is provided. Carbamoylnitrile oxide generated from nitroisoxazolone underwent inverse electron-demand 1,3-dipolar cycloaddition with 1,3-dicarbonyl compounds in the presence of magnesium
975+15 more
core +1 more source
Isoxazole derivatives as new nitric oxide elicitors in plants
Several 3,5-disubstituted isoxazoles were obtained in good yields by regiospecific 1,3-dipolar cycloaddition reactions between aromatic nitrile oxides, generated in situ from the corresponding hydroxyimidoyl chlorides, with non-symmetrical activated ...
Anca Oancea+9 more
doaj +1 more source
Method of identifying inhibitors of glutathione S-transferase (GST) gene expression [PDF]
Complementary DNA and genomic clones for three variants of GST-.pi. are disclosed. It is demonstrated that certain of these variants are overexpressed in gliomas, thereby indicating an involvement with that form of cancer.
Akande, Olanike+6 more
core +1 more source