Results 21 to 30 of about 20,875 (302)

Simple Access to Isoxazole-Containing Heterocyclic Hybrids: Isoxazole/Oxazole and Isoxazole/Pyridine

open access: yesRussian Journal of General Chemistry, 2023
Abstract The synthesis of substituted isoxazole–oxazole hybrids by the noncatalytic reaction of methyl 2-diazo-2-(alkyl/aryl/hetarylisoxazol-5-yl)acetates with alkyl and aryl cyanides has been reported. According to DFT calculations, the reaction proceeds through the intermediate formation of a nitrile ylide and its ...
A. E. Taishev   +3 more
openaire   +1 more source

A Facile Approach to Bis(isoxazoles), Promising Ligands of the AMPA Receptor

open access: yesMolecules, 2021
A convenient synthetic approach to novel functionalized bis(isoxazoles), the promising bivalent ligands of the AMPA receptor, was elaborated.
D. Vasilenko   +11 more
semanticscholar   +1 more source

Synthesis of new 3,5-substiuted isoxazole derivatives possessing potential anti-aggregative activity

open access: greenТонкие химические технологии, 2010
Two new compounds belonging to 3,5-substituted isoxazoles class were synthesized for the action mechanism investigation and the pharmacophore fragment determination of potential anti-aggregative compounds of this class.
O. V. Demina   +8 more
doaj   +1 more source

An overview of metal-free synthetic routes to isoxazoles: the privileged scaffold

open access: yesRSC Advances, 2021
In the field of drug discovery, isoxazole is a five-membered heterocyclic moiety commonly found in many commercially available drugs. In view of their enormous significance, it is always imperative to unleash new eco-friendly synthetic strategies.
Soumyadip Das, K. Chanda
semanticscholar   +1 more source

MnVI-NP–Catalyzed Generation of Nitrile Oxides: Easy Access to Isoxazolines and Isoxazoles via Stereoselective 1,3-Dipolar Cyclo­addition Reactions

open access: yesSynOpen, 2022
The versatility and effectiveness of MnVI-NPs as a catalyst is examined for the generation of nitrile oxides from aldoximes and subsequent 1,3-dipolar cycloaddition reactions.
Yasmin Saima, Saikat Khamarui
doaj   +1 more source

Facile synthesis of isoxazoles and pyrazoles from ß-diketohydrazones [PDF]

open access: yes, 2009
Indexación: ScieloNew 3,5-dimethyl-4-[(E)-4-(R1-phenyl)diazenyl]isoxazoles and 3,5-dimethyl-1-(R2-phenyl)-4-[(E)-(R1-phenyl)diazenyl]-1H-pyrazoles may be obtained by reaction of 3-[2-(R1-phenyl)hydrazono)]pentane-2,4-dione with H2NOH-HCl and R2-4-C6H4 ...
Bustos, Carlos   +4 more
core   +1 more source

Büchwald-Hartwig reaction applied to synthesis of new luminescent liquid crystal triarylamines derived from isoxazoles [PDF]

open access: yes, 2015
© 2015 Taylor & Francis Group, LLC. The present work describes the synthesis and characterization of novel series of triarylamines isoxazoles (TAA) addressed to the organic photovoltaic materials. Diarylisoxazoles were synthesized by sequential [3+2] 1,
Fernandes, T. H. M.   +3 more
core   +2 more sources

[3 + 2] Cycloaddition reactions of nitrile oxides generated in situ from aldoximes with alkenes and alkynes under ball-milling conditions

open access: yesGreen Chemistry Letters and Reviews, 2022
A convenient and efficient [3 + 2] cycloaddition reaction of alkenes and alkynes with the in situ generated nitrile oxides from aldoximes in the presence of NaCl, Oxone and Na2CO3 has been developed to afford a series of isoxazoles and isoxazolines at ...
Run-Kai Fang   +3 more
doaj   +1 more source

Synthesis of 3,5-Disubstituted Isoxazoles and Isoxazolines in Deep Eutectic Solvents [PDF]

open access: yes, 2015
The synthesis of different 3,5-disubstituted isoxazoles and related isoxazolines using choline chloride:urea as deep eutectic solvent (DES) in a one-pot three step reaction has been accomplished successfully. The use of highly nucleophilic functionalized
Pérez Galera, Juana María   +1 more
core   +3 more sources

Chalcones as versatile synthons for the synthesis of 5- and 6-membered nitrogen heterocylces [PDF]

open access: yes, 2014
Chalcones belong to the flavonoid family which constitutes one of the major classes of naturally occurring oxygen heterocyclic compounds. The alpha,beta-unsaturated carbonyl system of chalcones possesses two electrophilic reactive centers allowing them ...
Albuquerque, Hélio   +3 more
core   +1 more source

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