Results 71 to 80 of about 19,238 (306)
A Two-Step Synthesis of Unprotected 3-Aminoindoles via Post Functionalization with Nitrostyrene
Molecules, 2023 A novel, low-cost method for the preparation of not easily accessible free 3-aminoindoles has been developed. This approach is based on a well-established reaction between indoles and nitrostyrene in the presence of phosphorous acid, which results in the
Nicolai A. Aksenov +9 more
doaj +1 more source
Arabian Journal of Chemistry, 2019 3,6-Dimethyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one 3 was prepared by an intramolecular cyclization of N-(4-cyano-3-methyl-1-phenyl-1H-pyrazol-5-yl) acetamide 2 in ethanol in the presence of piperidine.
Ameur Rahmouni +5 more
doaj
Simple Access to Isoxazole-Containing Heterocyclic Hybrids: Isoxazole/Oxazole and Isoxazole/Pyridine
Russian Journal of General Chemistry, 2023 Abstract The synthesis of substituted isoxazole–oxazole hybrids by the noncatalytic reaction of methyl 2-diazo-2-(alkyl/aryl/hetarylisoxazol-5-yl)acetates with alkyl and aryl cyanides has been reported. According to DFT calculations, the reaction proceeds through the intermediate formation of a nitrile ylide and its ...
A. E. Taishev +3 more
openaire +1 more source
Journal of Organic Chemistry, 2019 A facile synthetic route towards either 3- or 5-fluoroalkyl-substituted isoxazoles or pyrazoles containing an additional functionalization site was developed and applied on a multigram scale.
B. Chalyk +9 more
semanticscholar +1 more source
Benzochalcogenodiazoles, synthesis and applications in medicinal chemistry and photomedicine.
European Journal of Organic Chemistry, Accepted Article.Benzochalcogenodiazoles BXDs (BOD: benzoxadiazole, BTD: benzothiadiazole, or BSD: benzoselenadiazole) are aromatic bicyclic compounds, containing chalcogen atoms, with applications ranging from material to medicinal chemistry. The recent developments in their preparation and functionalization are taking advantage of new methodologies such as C‐H ...
Jean-Elie Zheng +2 more
wiley +1 more source
ChemistryOpen, 2019 Anthracenenitrile oxide undergoes 1,3‐dipolar cycloaddition reaction with propargyl bromide affording the expected isoxazole as single regioisomer, suitably synthetically elaborated and functionalized with a protected triple bond.
Dr. Mattia Moiola +7 more
doaj +1 more source
Synthesis and Antimicrobial Evaluation of Some Heterocyclic Chalcone Derivatives
Molecules, 2011 Some new heterocyclic compounds containing isoxazole, pyrazole and oxadiazole ring systems were prepared from various chalcones. The synthesized compounds have been characterized by elemental analysis and spectral methods.
Essam Mohamed Sharshira +1 more
doaj +1 more source
Synthesis of Isoxazoles via Electrophilic Cyclization. [PDF]
ChemInform, 2005 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Richard C. Larock, Jesse Waldo
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Chemical Science, 2019 Gold-catalyzed bicyclic annulations of 4-methoxy-1,2-dienyl-5-ynes with isoxazoles afford indolizine derivatives; the reaction mechanism involves alkyne attack on a gold π-allene to yield a vinyl gold carbene.
Antony Sekar Kulandai Raj +4 more
semanticscholar +1 more source
Effects of perampanel on bone health in adult patients with epilepsy
Epilepsia Open, EarlyView.Abstract Objective The objective was to assess the effects of perampanel (PER) on bone metabolism and bone mineral density (BMD) in adult patients with epilepsy. Methods This retrospective study included consecutive patients admitted to the Epilepsy Center of Sichuan Provincial People's Hospital from January 2023 to June 2024.
Mingxing Yu +8 more
wiley +1 more source