Results 71 to 80 of about 113,930,362 (191)

Therapeutic implication of ‘Iturin A’ for targeting MD-2/TLR4 complex to overcome angiogenesis and invasion

open access: yes, 2017
Tumor angiogenesis and invasion are deregulated biological processes that drive multistage transformation of tumors from a benign to a life-threatening malignant state activating multiple signaling pathways including MD-2/TLR4/NF-κB.
Ojha, Probir Kumar   +21 more
core   +1 more source

Marine lipopeptide Iturin A inhibits Akt mediated GSK3β and FoxO3a signaling and triggers apoptosis in breast cancer [PDF]

open access: yes, 2015
Akt kinase is a critical component of the PI3K/Akt signaling pathway, which is frequently over expressed in human cancers including breast. Therapeutic regimens for inhibiting breast cancer with aberrant Akt activity are essential.
Dhanarajan, Gunaseelan   +7 more
core   +1 more source

Comparing methods for identifying Bacillus strains capable of producing the antifungal lipopeptide iturin A

open access: yes, 2014
Lipopeptides represent a unique class of bioactive microbial secondary metabolites, and iturin A shows attractive antibiotic properties among them.
Hsieh, F.C.   +4 more
core   +1 more source

Targeted transcriptional and proteomic studies explicate specific roles of Bacillus subtilis iturin A, fengycin, and surfactin on elicitation of defensive systems in mandarin fruit during stress.

open access: yesPLoS ONE, 2019
Application of Bacillus cyclic lipopeptides (CLPs); fengycin, iturin A and surfactin has shown a great potential in controlling the spread of green mold pathogen invasion (Penicillium digitatum) in wounded mandarin fruit during postharvest period.
Paiboon Tunsagool   +5 more
doaj   +1 more source

Iturin AL - A new long chain iturin a possessing an unusual high content of C16-.BETA.-amino acids.

open access: yesThe Journal of Antibiotics, 1983
From a strain of Bacillus subtilis a new antifungal peptidolipid complex of the iturin group was isolated. This antibiotic complex contained six lipophilic beta-amino acids with 3-amino-14-methylpentanoic acid as the predominant component. Iturin AL contains: 2 D-Asp, 1 L-Asp, 1 L-Glu, 1 L-Pro, 1 L-Ser, 1 D-Tyr and a mixture of 2.9% iso-C14-beta-amino ...
G, Winkelmann   +3 more
openaire   +3 more sources

Optical and fluorescence microscopy analyses of FG treated with and without iturin A and plipastatin A.

open access: yes, 2015
In control treatment (CK), conidia showed typical canoe shape and widespread fluorescence; hyphae had equal widths, even surfaces, and symmetrically distributed branching, with strong fluorescence along hyphae.
An-Dong Gong (692780)   +7 more
core   +1 more source

Biological control of Pythium ultimum and Fusarium solani by indigenous strains Bacillus subtilis [PDF]

open access: yesBiological Journal of Microorganism, 2017
Introduction: Different Bacillus subtilis products of secondary metabolits include iturin lipopeptids, that may control plant disease effectively. The aim of this study was to investigate the antifungal activity of Indigenous strains Bacillus subtilis ...
Afagh Mohamady   +2 more
doaj  

Characterization of Bacillus amyloliquefaciens DA12 Showing Potent Antifungal Activity against Mycotoxigenic Fusarium Species

open access: yesThe Plant Pathology Journal, 2017
In an attempt to develop a biological control agent against mycotoxigenic Fusarium species, we isolated Bacillus amyloliquefaciens strain DA12 from soil and explored its antimicrobial activities.
Theresa Lee   +13 more
doaj   +1 more source

DataSheet1_Enhanced iturin a production in a two-compartment biofilm reactor by Bacillus velezensis ND.docx

open access: yes, 2023
In this study, a two-compartment biofilm reactor was designed for iturin A production. The biofilm reactor consists of a stirred-tank fermentor containing exclusively suspended cells and a packing column where the biofilm is attached.
Zhongmin Tang (3858142)   +4 more
core   +1 more source

Pre-clinical risk assessment and therapeutic potential of antitumor lipopeptide ‘Iturin A’ in an in vivo and in vitro model [PDF]

open access: yes, 2016
Lipopeptides are versatile bio-active weapons having antifungal, antibacterial, antimycoplasma and anticancer properties. In this study, the therapeutic potential and safety assessment of a lipopeptide molecule ‘Iturin A’ were evaluated.
Das, Anjan Kumar   +9 more
core   +1 more source

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