Results 81 to 90 of about 4,990 (166)

A Review on JC Virus Infection in Kidney Transplant Recipients

Clinical and Developmental Immunology, 2013
The polyomavirus (PyV), JC virus (JCV), is a small nonenveloped DNA virus that asymptomatically infects about 80% of healthy adults and establishes latency in the kidney tissue.
Serena Delbue, Mariano Ferraresso, Luciana Ghio, Camilla Carloni, Silvia Carluccio, Mirco Belingheri, Alberto Edefonti, Pasquale Ferrante   +7 more
doaj   +1 more source

A loop-mediated isothermal amplification assay for the detection and quantification of JC polyomavirus in cerebrospinal fluid: a diagnostic and clinical management tool and technique for progressive multifocal leukoencephalopathy

Virology Journal, 2018
Background JC polyomavirus (JCV) is the causative agent of progressive multifocal leukoencephalopathy (PML), a demyelinating disease of the central nervous system in immunosuppressed patients. PML usually has a poor prognosis.
Hitomi Kinoshita, Kazuo Nakamichi, Chang-Kweng Lim, Mutsuyo Takayama-Ito, Lixin Wang, Itoe Iizuka, Ichiro Kurane, Masayuki Saijo   +7 more
doaj   +1 more source

Evidence for modulation of BAG3 by polyomavirus JC early protein

Journal of General Virology, 2009
Polyomavirus JC (JCV) infects oligodendrocytes and astrocytes in the brain and is the cause of the demyelinating disease progressive multifocal leukoencephalopathy (PML). In cell culture, JCV infection is characterized by severe damage to cellular DNA, which begins early in infection, and a viral cytopathic effect, which is observed late in infection ...
Anna, Basile, Nune, Darbinian, Rafal, Kaminski, Martyn K, White, Antonio, Gentilella, Maria Caterina, Turco, Kamel, Khalili   +6 more
openaire   +2 more sources

JC Polyomavirus (JCV) and Monoclonal Antibodies: Friends or Potential Foes?

Clinical and Developmental Immunology, 2013
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system (CNS), observed in immunodeficient patients and caused by JC virus ((JCV), also called JC polyomavirus (JCPyV)).
Roberta Antonia Diotti, Akira Nakanishi, Nicola Clementi, Nicasio Mancini, Elena Criscuolo, Laura Solforosi, Massimo Clementi   +6 more
doaj   +1 more source

The importance of mouse models to define immunovirologic determinants of progressive multifocal leukoencephalopathy

Frontiers in Immunology, 2015
Progressive multifocal leukoencephalopathy (PML) is a severely debilitating and often fatal demyelinating disease of the central nervous system (CNS) in immunosuppressed individuals caused by JC polyomavirus (JCV), a ubiquitous human pathogen ...
Aron eLukacher, Elizabeth eFrost
doaj   +1 more source

JC polyomavirus-associated nephropathy in a kidney transplant recipient

BMJ Case Reports
This report describes a man in his late 50s who underwent donation-after-circulatory-death kidney transplantation in 2012, due to end-stage kidney disease of unknown origin. More than a decade post-transplant, he presented with a progressive decline in graft function after maintenance immunosuppression had been reduced due to multiple skin carcinomas ...
Wouter T Moest, Joris I Rotmans, Gijs Fortrie, Henny G Peltenburg, Jesper Kers, Mariet C W Feltkamp, Aiko P J de Vries   +6 more
openaire   +2 more sources

Prevalence of JC Polyomavirus in Patients with Neuroinvasive Disease of Unknown Etiology in Croatia. [PDF]

Medicina (Kaunas), 2023
Vilibic-Cavlek T, Bogdanic M, Peric T, Radmanic L, Antolasic L, Milasincic L, Zidovec-Lepej S.   +6 more
europepmc   +1 more source

JC Polyomavirus Modifies the Expression of Human microRNAs in Progressive Multifocal Leukoencephalopathy Brain. [PDF]

J Infect Dis, 2023
Honkimaa A, Suppula J, Tynninen O, Saarela M, Liimatainen H, Laine P, Auvinen P, Auvinen E.   +7 more
europepmc   +1 more source

Comprehensive proteomic analysis of JC polyomavirus-infected human astrocytes and their extracellular vesicles. [PDF]

Microbiol Spectr, 2023
Oberholster L, Mathias A, Perriot S, Blaser E, Canales M, Jones S, Culebras L, Gimenez M, Kaynor GC, Sapozhnik A, Richetin K, Goelz S, Du Pasquier R.   +12 more
europepmc   +1 more source

Case report: JC polyomavirus nephropathy in simultaneous heart-kidney transplantation: the role of viral-specific in situ hybridization staining. [PDF]

Front Med (Lausanne), 2023
Abu Jawdeh BG, Smith ML, Hudson MR, Mour GK, Budhiraja P, Rosenthal JL.   +5 more
europepmc   +1 more source