Results 61 to 70 of about 5,167 (169)

Diagnostic assays for polyomavirus JC and progressive multifocal leukoencephalopathy [PDF]

Reviews in Medical Virology, 2015
SummaryProgressive multifocal leukoencephalopathy (PML) is a devastating and often fatal demyelinating disease of the central nervous system for which effective therapies are lacking. It is caused by the replication of polyomavirus JC (JCV) in the oligodendrocytes and astrocytes leading to their cytolytic death and loss of myelin from the subcortical ...
White MK, Sariyer IK, Gordon J, Delbue S, PIETROPAOLO, Valeria Antonietta, Berger JR, Khalili K.   +6 more
openaire   +3 more sources

Progressive multifocal leukoencephalopathy in a lung transplant recipient: Isolation of John Cunningham (JC) virus from bronchoalveolar lavage

Journal of Global Infectious Diseases, 2016
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by polyomavirus John Cunningham (JC) virus.
Tanmay S Panchabhai, Chirag Choudhary, Carlos Isada, Erik Folch, Atul C Mehta   +4 more
doaj   +1 more source

Beyond Human Papillomavirus (HPV): Detection of EBV and Polyomaviruses in Cervical and Anal Samples

Journal of Medical Virology, Volume 98, Issue 4, April 2026.
ABSTRACT Colorectal and cervical cancers represent an important public health problem worldwide, particularly in Brazil. Colorectal cancer is one of the most frequently diagnosed malignancies worldwide and the most common cancer in both men and woman in Brazil.
Ana Carolina Silva Guimarães, Luana L. S. Rodrigues, Letícia Bomfim Campos, Katrini G. Martinelli, Nathália Silva Carlos Oliveira, W. Martin Kast, Charlotte A. Gaydos, Carlos Silva de Jesus, José H. Pilotto, Mariza G. Morgado, Tarik Gheit, Vanessa Salete de Paula   +11 more
wiley   +1 more source

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source

Role of BK Virus CTLs in the Treatment of BK Virus–Associated Nephropathy in Kidney‐Transplant and Hematopoietic Cell Transplant Recipients

Transplant Infectious Disease, Volume 28, Issue 2, March/April 2026.
Third‐party, BK virus‐specific cytotoxic T lymphocytes (CTLs) were safe and effective in reducing viremia in kidney and stem cell transplant recipients with BK virus nephropathy. However, they did not improve kidney function. Earlier administration may be more beneficial before nephropathy and irreversible damage occur.
Amanda Olson, Ye Ethan Li, Rafet Basar, Pinaki Banerjee, Indresh Kaur, Glorette Abueg, Melihate Sylejmani, Nadima Uprety, Rejeena Shrestha, Francia Reyes Silva, Valda Page, Richard E. Champlin, Dimitrios P. Kontoyiannis, Roy F. Chemaly, Elizabeth J. Shpall, Linda Moore, Osama A. Gaber, Katayoun Rezvani, Ala Abudayyeh   +18 more
wiley   +1 more source

Characterization of Cells Transformed by the Human Polyomavirus JC Virus

Journal of General Virology, 1986
One unique feature of the prototype JC virus (JCV) (Mad 1) genome is the occurrence of a second TATA sequence within the early promoter region. A naturally occurring oncogenic variant of JCV (Mad 4) lacks this second TATA box. Several cell lines transformed by Mad 1, Mad 4 and simian virus 40 were characterized, in part to investigate whether the ...
C W, Mandl, R J, Frisque
openaire   +2 more sources

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, Volume 66, Issue S2, Page S29-S44, September 2026.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source

Impact of Infection‐Related Immune Responses on ANCA‐Associated Vasculitis in Finns: A Mendelian Randomization Study

Genetics Research , Volume 2026, Issue 1, 2026.
Background ANCA‐associated vasculitis (AAV) includes microscopic polyarteritis (MPA), granulomatosis with polyangiitis (GPA), and eosinophilic granulomatosis with polyangiitis (EGPA). Studies have revealed that infection‐related immune responses could trigger vasculitis.
Naidan Zhang, Caixia Ji, Tong Lv, Xiao Bao, Neetu Rawal   +4 more
wiley   +1 more source

Belatacept and the Risk of Cytomegalovirus, BK Polyomavirus, and Epstein–Barr Virus Post‐transplant Lymphoproliferative Disease After Kidney Transplantation: A Meta‐Analysis and Systematic Review

Journal of Transplantation, Volume 2026, Issue 1, 2026.
Background The long‐term risk of cytomegalovirus (CMV), Epstein–Barr virus (EBV)‐associated post‐transplant lymphoproliferative disorder (PTLD), and BK viral infections from belatacept is unclear. This review aimed to evaluate these outcomes. Methods Several databases were reviewed from inception through September 2025 using the keywords “belatacept ...
Cybele Lara R. Abad, Raymund R. Razonable, Richa Sharma   +2 more
wiley   +1 more source

Viral Genomic Characterization and Replication Pattern of Human Polyomaviruses in Kidney Transplant Recipients

Viruses, 2020
Human Polyomavirus (HPyV) infections are common, ranging from 60% to 100%. In kidney transplant (KTx) recipients, HPyVs have been associated with allograft nephropathy, progressive multifocal leukoencephalopathy, and skin cancer.
Lucia Signorini, Maria Dolci, Evaldo Favi, Caterina Colico, Mariano Ferraresso, Rosalia Ticozzi, Giuseppe Basile, Pasquale Ferrante, Serena Delbue   +8 more
doaj   +1 more source