Saikosaponin b1 attenuates liver fibrosis by competitively disrupting the interaction between signal transducer and activator of transcription 3 (STAT3) and glioma‐associated oncogene‐1 (Gli1) in the activated hepatic stellate cells (HSCs). The blocked interaction of STAT3 and Gli1 promotes the degradation of Gli1, inhibits Gli1 transcriptional ...
Meiyu Shao+15 more
wiley +1 more source
Typing of human polyomavirus JC virus on the basis of restriction fragment length polymorphisms [PDF]
Yoshiaki Yogo+4 more
openalex +1 more source
ABSTRACT Objectives To determine if the assessment of CD8+ tumor‐infiltrating lymphocytes (TILs) adds prognostic information to the PD‐L1 combined positive score (CPS) in recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC). Methods A retrospective case series was performed of 77 patients with R/M HNSCC between 2003 and 2019.
Catherine T. Haring+8 more
wiley +1 more source
The POU domain protein Tst-1 and papovaviral large tumor antigen function synergistically to stimulate glia-specific gene expression of JC virus. [PDF]
Karin Renner+2 more
openalex +1 more source
Kidney Allograft Dysfunction Due to John Cunningham (JC) Virus Nephropathy. [PDF]
Sharma N, Abdulkhalek S.
europepmc +1 more source
A novel sequence-specific DNA-binding protein, LCP-1, interacts with single-stranded DNA and differentially regulates early gene expression of the human neurotropic JC virus [PDF]
Hayato Tada, Kamel Khalili
openalex +1 more source
Deep Sequencing and Molecular Characterisation of BK Virus and JC Virus WHO International Reference Materials for Clinical Diagnostic Use. [PDF]
Govind S+7 more
europepmc +1 more source
A 53 kDa protein binds to the negative regulatory region of JC virus early promoter [PDF]
Arun K. Sharma, Gyanendra Kumar
openalex +1 more source
Teaching NeuroImage: Cerebellar Atrophy Due to JC Virus Granule Cell Neuronopathy: A Clinical Syndrome Distinct From Classic PML. [PDF]
Silva-Rosas C+3 more
europepmc +1 more source
The pivotal image findings of progressive multifocal leukoencephalopathy: A case report
Progressive multifocal leukoencephalopathy (PML) is a rare disease associated with the reactivation of the JC virus, particularly in immunocompromised patients.
Shou-De Ma+4 more
doaj +1 more source