INVOLVEMENT OF JNK MAPK CASCADES IN THE FORMATION OF ADHESIONS IN THE ABDOMINAL CAVITY
Adhesive process in the abdominal cavity is one of the most frequent complications of intra-abdominal surgery.The aim of the study was to evaluate the activation of the JNK MAPK cascade during the experimental adhesion process.Materials and methods ...
I. A. Shurygina +4 more
doaj +1 more source
The functional contrariety of JNK [PDF]
AbstractThe JNK proteins are activated by multiple and diverse stimuli, leading to varied and seemingly contradictory cellular responses. In particular, JNKs have been reported to have a role in the induction of apoptosis, but have also been implicated in enhancing cell survival and proliferation. Thus the JNK proteins seem to represent an archetype of
Ann M, Bode, Zigang, Dong
openaire +2 more sources
Heat shock protein 90 mediates the protective effects of vericiguat on myocardial ischemia/reperfusion injury by inhibiting toll-like receptor 4 and c-Jun N-terminal kinases [PDF]
Objective(s): This study aimed to investigate whether vericiguat exerts a protective effect against myocardial ischemia-reperfusion injury (MIRI) by inhibiting toll-like receptor 4 (TLR4) and c-Jun N-terminal kinases (JNK) activation and whether heat ...
Sijie Pan +7 more
doaj +1 more source
Renal cell carcinoma (RCC) is generally acknowledged as the most resistant primary malignancy unresponsive to conventional radiotherapy and chemotherapy treatments.
Huang Shuaishuai +5 more
doaj +1 more source
c-Myc (Myc) is a well-known transcription factor that regulates many essential cellular processes. Myc has been implicated in regulating anti-mycobacterial responses.
Feng-Ling Luo (13211640) +6 more
core +1 more source
Estudi del factor de transcripció Cabut en el desenvolupament i la regeneració de Drosophila melanogaster [PDF]
[cat] El procés de regeneració permet als organismes refer parts o teixits del seu cos que han sofert algun dany. Els discs imaginals de Drosophila melanogaster, primordis larvaris de les estructures adultes, tenen capacitat de promoure processos de ...
Ruiz Romero, Marina
core +3 more sources
Serum CA19-9 and CEA levels, serum CAT, GSH, oxidised glutathione levels, 8-dihidro-2'-deoksiguanosina and F2-isoprostanes levels in colorectal cancer patients and Lactobacillus: A randomised double-blind controlled trial [PDF]
Background: Oxidative stress (OS) plays a crucial role in colorectal cancer (CRC) progression. Lactobacillus has been proposed as a potential modulator of OS. This randomised controlled trial aimed to evaluate the effects of Lactobacillus supplementation
Chen Shiru +5 more
doaj +1 more source
Cell-to-cell communication mediates glioblastoma progression in Drosophila
Glioblastoma (GB) is the most aggressive and lethal tumour of the central nervous system (CNS). GB cells grow rapidly and display a network of projections, ultra-long tumour microtubes (TMs), that mediate cell to cell communication.
Marta Portela +2 more
doaj +1 more source
JNK and p38 gene and protein expression during liver ischemia-reperfusion in a rat model treated with silibinin [PDF]
Objective(s): Signal transduction of mitogen-activated protein kinases (MAPKs) is activated during ischemia. In this study, c-Jun N-terminal Kinase (JNK) and p38 MAPK (p38) gene and protein expression were evaluated as two members of the MAPK family ...
Nastaran Aamani +4 more
doaj +1 more source
C-Jun N-terminal kinases/c-Jun and p38 pathways cooperate in ceramide-induced neuronal apoptosis [PDF]
Understanding the regulation of the apoptotic program in neurons by intracellular pathways is currently a subject of great interest. Recent results suggest that c-Jun N-terminal kinases (JNK), mitogen-activated protein kinases and the transcription ...
Brugg, B. +4 more
core +1 more source

