Results 41 to 50 of about 164,331 (306)
, 2022 c-Myc (Myc) is a well-known transcription factor that regulates many essential cellular processes. Myc has been implicated in regulating anti-mycobacterial responses.
Feng-Ling Luo (13211640) +6 more
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The role of JNK in the proinflammatory action of the SARS-CoV-2 protein ORF3a [PDF]
Medicinski PodmladakIntroduction: Coronavirus disease 2019 (COVID-19) is a contagious respiratory infection caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Aranđelović Lena +4 more
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SFRP1 suppresses granulosa cell proliferation and migration through inhibiting JNK pathway
Clinical and Experimental Obstetrics & Gynecology, 2021 Background: Secreted frizzled-related protein 1 (SFRP1) functions as a Wnt antagonist to repress the proliferation and migration of epithelial ovarian cancer cells.
Shan Zhou, Liang Xia, Liyuan Han
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Poly(ADP-ribose) polymerase family member 14 (PARP14) is a novel effector of the JNK2-dependent pro-survival signal in multiple myeloma [PDF]
, 2013 Copyright @ 2013 Macmillan Publishers Limited. This is the author's accepted manuscript. The final published article is available from the link below.Regulation of cell survival is a key part of the pathogenesis of multiple myeloma (MM).
Papa, S +9 more
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Molecules and Cells, 2006 The literature provides strong precedent for both pro-tumorigenic and tumor suppressor roles for the c-Jun N-terminal kinases (JNKs) in the setting of oncogenesis. Clearly, JNKs are activated by numerous oncogenes and growth factors and the literature documents a role for these MAP kinases in cell proliferation and transformation.
Lynn E, Heasley, Sun-Young, Han
openaire +2 more sources
, 2023 Graphical illustration of the IRE1-JNK-Beclin 1 signaling pathway involved in SADS-CoV-induced autophagy via PLP2-TM and GRP78 interaction.
Jianfei Chen (3186999) +19 more
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 3-alkyl-5-aryl-1-pyrimidyl-1H-pyrazole derivatives were designed and synthesised as selective inhibitors of JNK3, a target for the treatment of neurodegenerative diseases.
Youri Oh +6 more
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Role of c-Jun N-terminal Kinase (JNK) in Obesity and Type 2 Diabetes
Cells, 2020 Obesity has been described as a global epidemic and is a low-grade chronic inflammatory disease that arises as a consequence of energy imbalance. Obesity increases the risk of type 2 diabetes (T2D), by mechanisms that are not entirely clarified. Elevated
Justin Hou Ming Yung, Adria Giacca
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Requirement of JNK-mediated phosphorylation for translocation of group IVA phospholipase A2 to phagosomes in human macrophages [PDF]
, 2009 Eicosanoids are a broad family of lipids that play a critical role in host defense against bacterial and fungal infections. The first enzyme in the metabolic pathway for the generation of eicosanoids is group IVA phospholipase A2, also known as cytosolic
Meana González, Clara +6 more
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4 open, 2019 It is increasingly evident that carcinogenesis, in the vast majority of cancers, cannot be explained simply through an accumulation of somatic mutations, or epigenetics, the stem cell theory, or the Warburg effect.
Brücher Björn L.D.M., Jamall Ijaz S.
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