Results 1 to 10 of about 60 (59)
Genome-wide identification of the jumonji C domain- containing histone demethylase gene family in wheat and their expression analysis under drought stress [PDF]
Frontiers in Plant Science, 2022 Methylation and demethylation of histone play a crucial role in regulating chromatin formation and gene expression. The jumonji C (JmjC) domain-containing proteins are demethylases that are involved in regulating epigenetic modification in plants. In our
Xinhua Wang +12 more
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Biomolecules, 2021 Histone methylation tightly regulates chromatin accessibility, transcription, proliferation, and cell differentiation, and its perturbation contributes to oncogenic reprogramming of cells.
Hans Felix Staehle +2 more
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The JMJD Family Histone Demethylases in Crosstalk Between Inflammation and Cancer
Frontiers in Immunology, 2022 Inflammation has emerged as a key player in regulating cancer initiation, progression, and therapeutics, acting as a double edged sword either facilitating cancer progression and therapeutic resistance or inducing anti-tumor immune responses ...
Jia Yang +4 more
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Frontiers in Plant Science, 2022 Vernalization is the promotion of flowering after prolonged exposure to cold. In Arabidopsis thaliana, vernalization induces epigenetic silencing of the floral repressor gene FLOWERING LOCUS C (FLC).
Takashi Maruoka +4 more
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Targeting epigenetic regulators to overcome drug resistance in cancers
Signal Transduction and Targeted Therapy, 2023 Drug resistance is mainly responsible for cancer recurrence and poor prognosis. Epigenetic regulation is a heritable change in gene expressions independent of nucleotide sequence changes.
Nan Wang, Ting Ma, Bin Yu
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JMJD family proteins in cancer and inflammation
Signal Transduction and Targeted Therapy, 2022 The occurrence of cancer entails a series of genetic mutations that favor uncontrollable tumor growth. It is believed that various factors collectively contribute to cancer, and there is no one single explanation for tumorigenesis.
Wang Manni +4 more
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Biomolecules, 2021 Exposure to moderately high temperature enables plants to acquire thermotolerance to high temperatures that might otherwise be lethal. In Arabidopsis thaliana, histone H3 lysine 27 trimethylation (H3K27me3) at the heat shock protein 17.6C (HSP17.6C) and ...
Nobutoshi Yamaguchi, Toshiro Ito
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Frontiers in Plant Science, 2020 Abscisic acid (ABA) interacts antagonistically with brassinosteroids (BRs) to control plant growth and development in response to stress. The response to environmental cues includes hormonal control via epigenetic regulation of gene expression.
Jinfeng Wu +11 more
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Vitamin C and epigenetics: A short physiological overview
Open Medicine, 2023 In recent years, ascorbic acid (vitamin C) has acquired great interest due to its multiple functions, which results in homeostasis of normal tissues and organs. On the other hand, it has been shown that epigenetic modifications may have an important role
Pavlovic Voja +3 more
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Scientific Reports, 2022 JmjC (Jumonji-C) domain-containing 5 (JMJD5) plays important roles in circadian regulation in plants and humans and is involved in embryonic development and cell proliferation.
Md. Saiful Islam +3 more
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