Results 81 to 90 of about 606,579 (281)

Calorimetric readout of a superconducting proximity-effect thermometer

, 2009
A proximity-effect thermometer measures the temperature dependent critical supercurrent in a long superconductor - normal metal - superconductor (SNS) Josephson junction.
A.D. Zaikin, D.R. Schmidt, D.R. Schmidt, D.V. Averin, F. Giazotto, F. Giazotto, F.C. Wellstood, F.W.J. Hekking, H. Courtois, H. Courtois, H. Courtois, J. Bardeen, J. P. Pekola, J. T. Peltonen, M. Meschke, M. Meschke, M.A. Sillanpää, M.L. Roukes, M.M. Leivo, P. Dubos, R.C. Dynes, S. Rajauria, T.T. Heikkilä, W. Belzig   +23 more
core   +4 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Time-Dependent Optothermal Performance Analysis of a Flexible RGB-W LED Light Engine

Micromachines
The wide application of light emitting diodes (LEDs) in lighting systems has necessitated the inclusion of spectral tunability by using multi-color LED chips.
Md Shafiqul Islam, Mehmet Arik
doaj   +1 more source

Thermal Modeling of GaN HEMT Devices With Diamond Heat-Spreader

IEEE Journal of the Electron Devices Society, 2020
Harvesting the potential performance of GaN-based devices in terms of the areal power density and reliability, relies on the efficiency of their thermal management.
M. Mahrokh, Hongyu Yu, Yuejin Guo
doaj   +1 more source

Control of Coulomb blockade in a mesoscopic Josephson junction using single electron tunneling [PDF]

, 2003
We study a circuit where a mesoscopic Josephson junction (JJ) is embedded in an environment consisting of a large bias resistor and a normal metal - superconductor tunnel junction (NIS).
Delahaye, J., Hakonen, P., Hassel, J., Seppa, H.   +3 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Modeling and Analysis for Estimation of Junction Temperature Under Various Operating Conditions and Optimization of Pin-Fin Heat Sink for Automotive IGBT Modules

Applied Sciences
New energy vehicles (NEVs) rely heavily on Insulated-Gate Bipolar Transistors (IGBTs) to perform frequent battery voltage conversions for operations such as acceleration, deceleration, and hill climbing.
Chuncen Wu, Feng Wang, Yifan Song
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

INSULATED GATE BIPOLAR TRANSISTOR TEMPERATURE CALCULATION USING SIMSCAPE/SIMULINK ENVIRONMENT WITH VARIOUS SWITCHING FREQUENCY

Journal of Engineering and Sustainable Development
Because of developments in high-power converters, it has become crucial to investigate how effective inverter performance is. consequently, via being aware of the temperature value of the junction for the inverter switch.
Ahmed Shihab Ahmed, Riyadh Ghanim Omar
doaj   +1 more source

An online extraction method of junction temperature in IGBT devices with saturation voltage drop

机车电传动, 2023
The junction temperature, working performance, lifespan, and reliability of insulated gate bipolar transistor (IGBT) modules are closely related. Achieving online monitoring of IGBT junction temperature is of great significance to improve the reliability
WANG Zequn, TIAN Xiaoyu, SONG Zhiru, SONG Wensheng   +3 more
doaj