Results 41 to 50 of about 38,460 (214)
Renal and vascular effects of kallikrein inhibition in a model of Lonomia obliqua venom-induced acute kidney injury. [PDF]
PLoS Neglected Tropical Diseases, 2019 BACKGROUND:Lonomia obliqua venom is nephrotoxic and acute kidney injury (AKI) is the main cause of death among envenomed victims. Mechanism underlying L.
Markus Berger +10 more
doaj +1 more source
Role of Serine Proteases at the Tumor-Stroma Interface
Frontiers in Immunology, 2022 During tumor development, invasion and metastasis, the intimate interaction between tumor and stroma shapes the tumor microenvironment and dictates the fate of tumor cells.
Ravichandra Tagirasa, Euna Yoo
doaj +1 more source
BioMed Research International, 2015 Caffeine, pentoxifylline, and kallikrein are substances that affect the efficiency of sperms in the fertilization process; however, they have not been adequately studied.
Ibrahim A. H. Barakat +3 more
semanticscholar +1 more source
A Missing Link Between a High Salt Intake and Blood Pressure Increase
Journal of Pharmacological Sciences, 2006 .: It is widely accepted that a high sodium intake triggers blood pressure rise. However, only one-third of the normotensive subjects were reported to show salt-sensitivity in their blood pressure.
Makoto Katori, Masataka Majima
doaj +1 more source
The 3rd International Symposium on Kallikreins and Kallikrein-Related Peptidases [PDF]
Biological Chemistry, 2010 No abstract ...
Magdolen, Viktor +3 more
openaire +3 more sources
Involvement of Kallikrein-Related Peptidases in Normal and Pathologic Processes
Disease Markers, 2015 Human kallikrein-related peptidases (KLKs) are a subgroup of serine proteases that participate in proteolytic pathways and control protein levels in normal physiology as well as in several pathological conditions. Their complex network of stimulatory and
A. C. Stefanini +3 more
semanticscholar +1 more source
The complex role of kininogens in hereditary angioedema
Frontiers in Allergy, 2022 Human high molecular weight kininogen (HK) is the substrate from which bradykinin is released as a result of activation of the plasma “contact” system, a cascade that includes the intrinsic coagulation pathway, and a fibrinolytic pathway leading to the ...
Allen P. Kaplan +2 more
doaj +1 more source
European Urology, 2014 BACKGROUND The four-kallikrein panel and the Prostate Health Index (PHI) have been shown to improve prediction of prostate cancer compared to prostate-specific antigen (PSA).
T. Nordström +5 more
semanticscholar +1 more source
Inhibition of Plasma Kallikrein by a Highly Specific Active Site Blocking Antibody
Journal of Biological Chemistry, 2014 Background: Unregulated plasma kallikrein proteolytic activity can result from C1-inhibitor deficiency, causing excessive and potentially fatal edema. Results: The antibody DX-2930 potently and specifically inhibits plasma kallikrein and exhibits a long ...
J. Kenniston +20 more
semanticscholar +1 more source
Mechanisms involved in hereditary angioedema with normal C1-inhibitor activity
Frontiers in Physiology, 2023 Patients with the inherited disorder hereditary angioedema (HAE) suffer from episodes of soft tissue swelling due to excessive bradykinin production.
Aleksandr Shamanaev +9 more
doaj +1 more source