Results 21 to 30 of about 30,372 (240)

Role of human tissue kallikrein in gastrointestinal stromal tumour invasion [PDF]

, 2010
Background: Human tissue kallikrein (hK1) generates vasodilator kinins from kininogen and promotes angiogenesis by kinin-dependent and kinin-independent mechanisms.
Sharman, JA, Mangialardi, GMVU, Sharman, J.A., J A Sharman, Pignatelli, M., Campagnolo, P., H. Zadeh M, P Dominek, Spinetti G, Kränkel, N, Madeddu, P, Kränkel N, H-Zadeh, M., Emanueli, C., M Pignatelli, Spinetti, G., M Chilosi, H-Zadeh, M, A Caporali, Campagnolo P, Dominek, P., Pignatelli M, P Madeddu, Mangialardi G, M H-Zadeh, Emanueli C, N Kränkel, Caporali, A, Pignatelli, M, Spinetti, G, Madeddu, P., Chilosi, M., Mangialardi, G, Emanueli, C, Dominek, PK, Kraenkel, N, Sharman, J A, G Mangialardi, Caporali A, Dominek P, Sharman JA, Madeddu, PR, Mangialardi, G., CHILOSI, Marco, P Campagnolo, Chilosi, M, G Spinetti, Campagnolo, P, Madeddu P., Kränkel, N., C Emanueli, Caporali, A., Caporali, A; id_orcid, Dominek, P   +53 more
core   +1 more source

Molecular biology of the kallikrein-kinin system: from structure to function

Brazilian Journal of Medical and Biological Research, 1998
The participation of the kallikrein-kinin system, comprising the serine proteases kallikreins, the protein substrates kininogens and the effective peptides kinins, in some pathological processes like hypertension and cardiovascular diseases is still a ...
J.B. Pesquero, M. Bader
doaj   +1 more source

Transcriptional regulation of prostate kallikrein-like genes by androgen. [PDF]

, 1992
Using gene-specific synthetic oligonucleotides the expression and regulation of kallikrein-like genes in the human prostatic cancer cell line LNCaP were studied.
Schulz, Peter, Fittler, Friedrich, Wolf, Dieter A.   +2 more
core   +1 more source

New tools to study contact activation.

Frontiers in Medicine, 2016
The recent availability of a sensitive chromogenic method approach for determination of FXIa activity has been explored for designing sensitive methods for FXIIa and Kallikrein, both using FXa formation as the read-out. For both enzymes the assay range 1-
Steffen Rosén
doaj   +1 more source

Potassium Intake Prevents the Induction of the Renin-Angiotensin System and Increases Medullary ACE2 and COX-2 in the Kidneys of Angiotensin II-Dependent Hypertensive Rats

Frontiers in Pharmacology, 2019
In angiotensin II (Ang II)-dependent hypertensive rats there is an increased expression of proximal tubule angiotensinogen (AGT), collecting duct renin and angiotensin converting enzyme (ACE), which contributes to intratubular Ang II formation.
Alexis A. Gonzalez, Matias Gallardo, Carlos Cespedes, Carlos Cespedes, Carlos P. Vio, Carlos P. Vio   +5 more
doaj   +1 more source

Contact pathway in surgical and transcatheter aortic valve replacement

Frontiers in Cardiovascular Medicine, 2022
BackgroundAortic valve replacement is the gold standard treatment for severe symptomatic aortic stenosis, but thrombosis of bioprosthetic valves (PVT) remains a concern.ObjectiveTo analyze the factors involved in the contact pathway during aortic valve ...
María Eugenia de la Morena-Barrio, Javier Corral, Cecilia López-García, Víctor Alonso Jiménez-Díaz, Antonia Miñano, Pablo Juan-Salvadores, María Asunción Esteve-Pastor, José Antonio Baz-Alonso, Ana María Rubio, Francisco Sarabia-Tirado, Miguel García-Navarro, Juan García-Lara, Francisco Marín, Vicente Vicente, Eduardo Pinar, Sergio José Cánovas, Gonzalo de la Morena   +16 more
doaj   +1 more source

Interdependence of kallikrein-related peptidases in proteolytic networks [PDF]

, 2010
Human kallikrein-related peptidases (KLKs) are 15 homologous serine proteases involved in several (patho)physiological processes, including cancer. Secreted as precursors, they are activated upon proteolytic release of a short propeptide. We searched for
Burkhart, Julia M., Schwarz, Amelie, Christian Ries, Utzschneider, Daniel, Karolina Plaza, Debela, M., Amelie Schwarz, Plaza, Karolina, Beaufort, Nathalie, Creutzburg, Sabine, Ries, C., Schmitt, M., Burkhart, J. M., Beaufort, N., Plaza, K., Ries, Christian, Schwarz, A., Sabine Creutzburg, Mekdes Debela, Creutzburg, S., Schmitt, Manfred, Utzschneider, D., Julia M. Burkhart, Magdolen, Viktor, Debela, Mekdes, Viktor Magdolen, Nathalie Beaufort, Magdolen, V., Beaufort, N;Plaza, K;Utzschneider, D;Schwarz, A;Burkhart, JM;Creutzburg, S;Debela, M;Schmitt, M;Ries, C;Magdolen, V   +28 more
core   +1 more source

A comprehensive nomenclature for serine proteases with homology to tissue kallikreins [PDF]

, 2006
The human kallikrein locus on chromosome 19q13.3-13.4 contains kallikrein 1 - the tissue kallikrein - and 14 related serine proteases. Recent investigations into their function and evolution have indicated that the present nomenclature for these proteins
Scorilas, Andreas, Malm, Johan,, Talieri, M, Courty, Yves, Ulf-Håkan Stenman, Lundwall, Åke,, Yousef, George M, Georgia Sotiropoulou, Lois J. Maltais, Talieri, Maroulio, Olsson, A Yvonne, Yousef, George, Talieri, M., Malm, Johan, Carsten Stephan, Stephan, Carsten, Blaber, M., Liija, H., Malm, J., Fritz, Hans, Petraki, C, Scorilas, A, Diamandis, EP, Blaber, Michael, Clements, Judith A, Lundwall, A., Lilja, Hans, Andreas Scorilas, Scorilas, A., Olsson, A. Yvonne, Hans Fritz, Judith A. Clements, Clements, JA, Fritz, H., Lundwall, Åke, Constantina Petraki, Maltais, Lois J, Sotiropoulou, Georgia, Clements, J A, Clements, Judith, Lilja, H, Lund University., Blaber, M, Olsson, AY, Vimla Band, A. Yvonne Olsson, Lundwall, A, Band, Vimla, Maroulio Talieri, Stephan, C., Sotiropoulou, G, Lilja, Hans,, Yousef, G M, Petraki, Constantina, Courty, Y, Fritz, H, Sotiropoulou, G., Courty, Y., Eleftherios P. Diamandis, Maltais, LJ, Åke Lundwall, Michael Blaber, Yousef, GM, Diamandis, Eleftherios P, Hans Lilja, Stenman, Ulf-Hakan, Diamandis, E P, Maltais, L J, Stephan, C, Petraki, C., George M. Yousef, Stenman, UH, Malm, J, Band, V, Yves Courty, Olsson, A Y, Band, V., Maltais, Lois, Diamandis, Eleftherios, Johan Malm   +79 more
core   +1 more source

Cleavage of the vaspin N-terminus releases cell-penetrating peptides that affect early stages of adipogenesis and inhibit lipolysis in mature adipocytes

Adipocyte, 2021
Vaspin expression and function is related to metabolic disorders and comorbidities of obesity. In various cellular and animal models of obesity, diabetes and atherosclerosis vaspin has shown beneficial, protective and/or compensatory action.
Catherine A. Tindall, Estelle Erkner, Jan Stichel, Annette G. Beck-Sickinger, Anne Hoffmann, Juliane Weiner, John T. Heiker   +6 more
doaj   +1 more source

Biochemistry and functional aspects of human glandular kallikreins [PDF]

, 1980
Human urinary kallikrein was purified by gel filtration on Sephacryl S-200 and affinity chromatography on aprotinin-Sepharose, followed by ion exchange chromatography on DEAE-Sepharose.
Geiger, Reinhard, Stuckstedte, Ulrike, Edwin Fink, Reinhard Geiger, Ulrike Stuckstedte, Förg-Brey, Bruni, Fink, Edwin, Bqruni Förg-Brey   +7 more
core   +1 more source