Results 101 to 110 of about 161,054 (247)
A case report on the long‐term use of teduglutide in a pediatric patient with short bowel syndrome
Nutrition in Clinical Practice, EarlyView.Abstract Short bowel syndrome (SBS) is the leading cause of intestinal failure, frequently necessitating long‐term parenteral nutrition (PN). Teduglutide (TED), a glucagon‐like peptide‐2 analog, has demonstrated efficacy in reducing PN dependence in both adults and children. However, long‐term data in pediatric populations remain limited.
Tsuyoshi Sakurai +8 more
wiley +1 more source
Structure and Mechanism of PhdC, a Prenylated‐Flavin Maturase
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT Prenylated flavin mononucleotide (prFMN) is a modified flavin cofactor required by the UbiD family of (de)carboxylase enzymes. While the reduced prFMNH2 form is produced by the flavin prenyltransferase UbiX, the corresponding two‐electron oxidized prFMNiminium form is required to support UbiD catalysis. Thus, oxidative maturation of prFMNH2 is
Dominic R. Whittall +4 more
wiley +1 more source
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT BorF is a short‐chain flavin reductase from a desert soil bacterium that uses NADH to reduce FAD to FADH2, which is used by the tryptophan‐6‐halogenase BorH to chlorinate tryptophan in the biosynthetic pathway of borregomycin A. The X‐ray crystal structure of BorF bound to FAD was solved to 2.37 Å by molecular replacement.
Zheng Ma +3 more
wiley +1 more source
Cell‐in‐Bead‐in‐Droplet Platform for pH‐Based Microfluidic Screening of Ureolytic Bacteria
Small, EarlyView.Efficient high‐throughput microbial screening in droplet microfluidics is often challenged by chemical crosstalk between droplets. This is particularly difficult in pH‐changing biological processes, for which more effective biochemical assays are needed.
Diego Giovanoli +8 more
wiley +1 more source
Small, EarlyView.A tri‐specific scaffold cell (TriSC) platform is engineered to enable programmable, reversible, and multiplex surface assembly through orthogonal and spontaneous coiled‐coil interactions. Independent targeting and therapeutic nanobodies are modularly recruited onto bacterial surfaces, allowing tunable combinatorial functionality.
Yong Joon Cho +3 more
wiley +1 more source
Veterinary Record, EarlyView.Abstract Background Changing legislation regarding antimicrobial consumption (AMC) forces Flemish bovine veterinary practitioners (BVP) to rethink their business models and shift their on‐farm practices from curative to preventive. However, little is known about their current practices and opinions regarding antibiotic stewardship, mastitis treatment ...
Lien Creytens +2 more
wiley +1 more source
World Journal of Surgery, EarlyView.Anastomotic leakage (AL) remains a severe complication after low anterior resection (LAR) for rectal cancer, despite advances in minimally invasive (MI) techniques. This study aimed to evaluate the impact of a surgery‐focused care bundle, implemented on an enhanced recovery after surgery (ERAS)‐based perioperative protocol, on preventing AL and ...
Koji Tamura +9 more
wiley +1 more source
Bicuculline reversal of aminoglycoside O-nucleotidyltransferase EanT-1-mediated kanamycin resistance. [PDF]
BMC MicrobiolWang J +8 more
europepmc +1 more source
Optimized bacterial expression of a synthetic BRIL antibody
Acta Crystallographica Section F, EarlyView.Here, we document the generation of a T7 Express ΔcybC strain allowing contaminant‐free expression of the anti‐BRIL Fab BAG2. We also report the crystal structure of BAG2 in complex with native cytochrome b562, a complex arising from expression in canonical Escherichia coli strains.The use of monoclonal fragments antigen binding (Fabs) is a prevalent ...
Benjamin F. Cooper, Georgia L. Isom
wiley +1 more source