Results 141 to 150 of about 164,663 (253)

Optimized TadA‐derived base editors efficiently manipulate mRNA splicing by A‐to‐G and C‐to‐K editing in potato

Journal of Integrative Plant Biology, EarlyView.
Two optimized TadA‐derived base editors efficiently generate diverse splicing variants by targeting specific splice sites in potato. ABSTRACT Pre‐messenger RNA (pre‐mRNA) splicing is a critical mechanism for post‐transcriptional regulation in plants. Through alternative splicing, plants produce diverse transcriptomes and proteomes that finely regulate ...
Kaiyuan Chen, Yan Zhang, Jiuzhou Deng, Lumin Zhang, Huiying Zhou, Yaxin Duan, Enle Xiao, Guangtao Zhu, Chunzhi Zhang   +8 more
wiley   +1 more source

Genome editing of susceptibility gene <i>StDND2</i> enhances <i>Phytophthora</i> resistance in <i>Solanum tuberosum</i>. [PDF]

Front Plant Sci
Bibi A, Ullah I, Aftab S, Amin I, Bibi B, Schneiter R.   +5 more
europepmc   +1 more source

SlMED25‐SlPHR3‐SlSPX2 module fine‐tunes SlPHR3‐mediated transcriptional activation of phosphate starvation response in tomato

Journal of Integrative Plant Biology, EarlyView.
The Mediator subunit SlMED25 and the co‐repressor SlSPX2 competitively bind the N‐terminal domain of the phosphate starvation response transcription factor SlPHR3 in tomato to form a sensitive molecular switch, which dynamically modulates phosphate starvation responses and maintains phosphate homeostasis, offering valuable targets for breeding low ...
Mingtong Zhai, Hongyu Han, Yu Zhang, Yunfeng Zhao, Hongying Guo, Hui Wang, Chuanlong Sun, Xianwen Meng, Lei Deng, Qian Chen, Chuanyou Li   +10 more
wiley   +1 more source

Occurrence of Antimicrobial-Resistant <i>Listeria monocytogenes</i> and <i>Listeria</i> spp. Recovered From Cattle Farms and the Factors Associated With Their Distribution in Mpumalanga and North West Provinces in South Africa. [PDF]

Vet Med Int
Moabelo KC, Mtshali NC, Moerane R, Gcebe N, Ngoshe YB, Adesiyun AA.   +5 more
europepmc   +1 more source

Identification and functional analysis of class 3 lipases associated with triacylglycerol metabolism in Nannochloropsis oceanica (Eustigmatophyceae)

Journal of Phycology, EarlyView.
Abstract Microalgae accumulate triacylglycerols (TAGs) as storage lipids in response to nutrient limitation, yet the mechanisms governing TAG turnover remain incompletely understood. In the oleaginous microalga Nannochloropsis oceanica, functional studies of TAG degradation have focused on lipases containing patatin domains, whereas the roles of other ...
Masako Iwai, Koichi Hori, Tomokazu Kurita, Kumiko Okazaki, Shinichiro Maeda, Akihide Takami, Takashi Yamamoto, Atsushi Sakamoto, Hiroyuki Ohta, Mie Shimojima   +9 more
wiley   +1 more source

Correlation between antimicrobial susceptibility data and clinical efficacy for <i>Helicobacter cinaedi</i> bacteraemia. [PDF]

JAC Antimicrob Resist
Araoka H, Tomida J, Yoshino C, Baba M, Ogura S, Kimura M, Kawamura Y.   +6 more
europepmc   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

A novel positive selection system for plant transformation based on microbial biuret hydrolase and biuret. [PDF]

PLoS One
Luo X, Yu Q, Hu D, Gong M, Zou Z.
europepmc   +1 more source

A Phosphorylation‐Dependent Partner‐Switching‐Like Module Regulates a Glycosyltransferase Required for Heterocyst Polysaccharide Layer Formation in Anabaena sp. Strain PCC 7120

Molecular Microbiology, EarlyView.
The glycosyltransferase All4160 is regulated by the reversible phosphorylation of Ser74. The kinase Alr3423 phosphorylates and inactivates All4160, while the SpoIIE‐like phosphatase HenR restores its activity through dephosphorylation. A nonphosphorylatable variant of All4160 bypasses the need for HenR, which demonstrates that a phosphorylation ...
Mai Harada, Satoshi Matsuoka, Shigeki Ehira   +2 more
wiley   +1 more source

Tumor-targeted aptamer-conjugated engineered bacteria for CXCL9 cytokine delivery in non-small cell lung cancer immunotherapy. [PDF]

J Transl Med
Gu Q, Wang R, Zhang L, Pan D, Bian C, Jia E, Chang J, Zhang H.   +7 more
europepmc   +1 more source