Results 41 to 50 of about 178,982 (291)

Supplementary Material to Synthesis and biological activity of some triazole-bearing benzimidazole derivatives [PDF]

open access: yesJournal of the Serbian Chemical Society, 2011
n ...
R. K. KHITOLIYA, C. LAL, K. F. ANSAR
doaj  

Phlorizin does not ameliorate kanamycin-induced ototoxicity.

open access: yes, 2014
Three weeks after dosing, mice treated with kanamycin in DPBS or mice treated with kanamycin plus DMSO (vehicle for phlorizin) had significant ABR threshold shifts at 32 kHz only compared to mice treated with DPBS only ...
Hongzhe Li (26250)   +5 more
core   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

A Novel Electrochemiluminescent Biosensor Based on Nitrogen-Doped Graphyne for Ultrasensitive Kanamycin Residue Detection in Milk and Honey Samples

open access: yesChemosensors
A novel sensitive and selective electrochemiluminescence (ECL) sensor using nitrogen-doped graphyne as the platform was proposed for kanamycin (KAN) detection.
Yuxuan Liu   +5 more
doaj   +1 more source

Conformational Response of 30S-bound IF3 to A-Site Binders Streptomycin and Kanamycin

open access: yesAntibiotics, 2016
Aminoglycoside antibiotics are widely used to treat infectious diseases. Among them, streptomycin and kanamycin (and derivatives) are of importance to battle multidrug-resistant (MDR) Mycobacterium tuberculosis.
Roberto Chulluncuy   +4 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Combination of kanamycin resistance and nitrate reductase deficiency as selectable markers in one nuclear genome provides a universal somatic hybridizer in plants [PDF]

open access: yes, 1987
The combination in the nuclear genome of a dominant resistance marker (to select against unfused wild-type cells) and a recessive deficiency marker (to select against unfused mutant cells) in a cell line should provide a system for selecting fusion ...
Brunold, Christian   +4 more
core   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Comparative Study of Erythrocyte Sedimentation Rate after Aminoglycoside and Aminocyclitol Treatment in Goats (Capra hircus)

open access: yesİstanbul Üniversitesi Veteriner Fakültesi Dergisi, 2016
The aim of the present study was to follow up the erythrocyte sedimentation rate (ESR) in healthy female goats during and after 5-day parenteral treatment with amikacin (10 mg/kg), tobramycin (5 mg/kg), apramycin (20 mg/kg), gentamicin (4 mg/kg ...
Toncho DINEV   +4 more
doaj   +1 more source

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