Results 71 to 80 of about 178,982 (291)

Investigation of METTL3 as an inhibitor of kanamycin-induced ototoxicity via stress granule formation

open access: yesFrontiers in Pharmacology
BackgroundMethyltransferase-like 3 (METTL3), a component of the N6-methyladenosine (m6A) methyltransferase family, exhibits significant expression in HEI-OC1 cells and cochlear explants.
Yan Wu   +13 more
doaj   +1 more source

Theoretical Studies on Mechanism of Inactivation of Kanamycin A by 4′-O-Nucleotidyltransferase

open access: yesFrontiers in Chemistry, 2019
This work is focused on mechanistic studies of the transfer of an adenylyl group (Adenoside-5′-monophosfate) from adenosine 5′-triphosphate (ATP) to a OH-4′ hydroxyl group of an antibiotic.
Sergio Martí   +2 more
doaj   +1 more source

Peritoneal transfer of kanamycin and its use in peritoneal dialysis [PDF]

open access: yes, 1973
Peritoneal transfer of kanamycin and its use in peritoneal dialysis. The effect of kanamycin administration on 15 functionally anephric chronic renal failure patients undergoing maintenance peritoneal dialysis was studied.
Despaux, Ernest   +5 more
core   +1 more source

A Disulfide‐Sticker Strategy for Marine Adhesive Coatings: From Deciphering Self‐Assembly Mechanism to Functional Application in Hair Regeneration

open access: yesAdvanced Science, EarlyView.
A disulfide‐sticker strategy, coupled with Ca2+ coordination, drives the hierarchical self‐assembly of a recombinant scallop adhesive protein into fishnet‐like nanostructures, affording a coating with versatile wet adhesion and intrinsic antioxidant activity. This biocompatible coating markedly promotes hair regeneration by activating follicular niches,
Lulu Wang   +7 more
wiley   +1 more source

IN VITRO AND IN VIVO SUSCEPTIBILITY OF MASTITIS PATHOGENS ISOLATED FROM BOVIN MASTITIS TO ANTIMICROBIAL DRUGS

open access: yesThe Iraqi Journal of Veterinary Medicine, 1992
The in vitro sensitivity testing of mastitis pathogens, associated with udder infections in cows, against 12 chemotherapeutic agents, showed that all strains (100%) tested are sensitive to gentamicin.
A. A. Yass
doaj   +1 more source

Co-Amorphization of Kanamycin with Amino Acids Improves Aerosolization

open access: yes, 2020
Different formulation techniques have been investigated to prepare highly aerosolizable dry powders to deliver a high dose of antibiotics to the lung for treating local infections. In this study, we investigated the influence of the co-amorphization of a
Shyamal C. Das   +4 more
core   +1 more source

A Phosphorylation‐Induced Micellization Switch in the Low‐Complexity Domain of TDP‐43

open access: yesAdvanced Science, EarlyView.
Phosphorylation of TAR DNA‐binding protein's 43 kDa (TDP‐43) low‐complexity domain by casein kinase 1 delta (CK1δ) acts as a molecular switch, redirecting its self‐assembly from macroscopic phase separation toward finite‐sized, spherical block‐copolymer micelles of ∼30 nm.
Rodrigo F. Dillenburg   +16 more
wiley   +1 more source

Additional file 1 of Diadenosine tetraphosphate modulated quorum sensing in bacteria treated with kanamycin

open access: yes, 2023
Additional file 1: Supplementary Figure 1. Screening Ap4A binding candidate proteins. Silver stain of the Ap4A binding candidate proteins after Ap4A-biotin immunoprecipitation (IP) with the protein lysate of 100 μg/ml kanamycin treatment or not treatment
Xia Ji (4101514)   +6 more
core   +1 more source

High‐Density E. Coli Cultivation Arrays for Combinatorial Drug Testing With Subsequent Lipid Profiling by MALDI‐MS

open access: yesAdvanced Science, EarlyView.
High‐throughput antibiotic cross‐gradient assays on microdroplet arrays. A multichannel printhead together with five pressure regulators forms droplet arrays of up to 20 832 droplets within 25 minutes. Each droplet contains unique concentrations of antibiotics, allowing to moniture a vast spectrum of bacterial repsonses over night. The bacterial growth
M. Breitfeld   +5 more
wiley   +1 more source

Immunoassay Analysis of Kanamycin in Serum Using the Tobramycin Kit [PDF]

open access: yes, 2016
Kanamycin is one of the aminoglycosides used in the treatment of multidrug-resistant tuberculosis. Blood concentrations of kanamycin are predictive for the treatment efficacy and the occurrence of side effects, and dose adjustments can be needed to ...
Touw, D J   +10 more
core   +2 more sources

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