Nuclear Transport of Yeast Proteasomes
Biomolecules, 2014 Proteasomes are conserved protease complexes enriched in the nuclei of dividing yeast cells, a major site for protein degradation. If yeast cells do not proliferate and transit to quiescence, metabolic changes result in the dissociation of proteasomes ...
Cordula Enenkel
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Reduced FBXW7 expression in pancreatic cancer correlates with poor prognosis, and chemotherapeutic resistance via accumulation of MCL1 [PDF]
, 2018 学位記番号 ...
Ishii, Norihiro +2 more
core
Secret life of importin-β; solenoid flexibility as the key to transport through the nuclear pore [PDF]
, 2016 open2siThe current issue of Acta Crystallographica Section D features ‘Impact of the crystal- lization condition on importin- conformation’ by Tauchert et al.
Alvisi, Gualtiero, Jans, David A.
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Calcium mediated regulation of karyopherin nuclear transport receptors
The FASEB Journal, 2013 Oxidative stress disrupts the normal function of cells and severe stress situations can result in apoptosis. A specific effect of oxidant stress is an increase in cellular calcium levels, which can be mimicked by treatment with the drug thapsigargin, which inhibits Ca 2+ uptake into the ...
Lauren Elizabeth Foltz +3 more
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Nuclear–Cytoplasmic Shuttling of the Usher Syndrome 1G Protein SANS Differs from Its Paralog ANKS4B
CellsThe USH1G protein SANS is a small multifunctional scaffold protein. It is involved in several different cellular processes, such as intracellular transport, in the cytoplasm, or splicing of pre-mRNA, in the cell nucleus.
Jacques S. Fritze +2 more
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Nuclear karyopherin α2 expression predicts poor survival in patients with advanced breast cancer irrespective of treatment intensity [PDF]
, 2008 Oleg Gluz +14 more
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BMC Cancer, 2018 Background Nucleocytoplasmic transport is a tightly regulated process carried out by specific transport machinery, the defects of which may lead to a number of diseases including cancer.
Elisa M. Vuorinen +3 more
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Disease-specific alteration of karyopherin-α subtype establishes feed-forward oncogenic signaling in head and neck squamous cell carcinoma [PDF]
, 2019 Masaharu Hazawa +11 more
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Regulation of cell cycle transcription factor Swi5 by karyopherin Msn5
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2012 Inactivation of S. cerevisiae β-karyopherin Msn5 causes hypersensitivity to the overexpression of mitotic cyclin Clb2 and aggravates growth defects of many mutant strains in mitotic exit, suggesting a connection between Msn5 and mitotic exit. We determined that Msn5 controlled subcellular localization of the mitotic exit transcription factor Swi5 ...
Taberner, Francisco José +4 more
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Changing expression and subcellular distribution of karyopherins during murine oogenesis [PDF]
, 2015 Bettina P. Mihalas +4 more
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