Results 111 to 120 of about 14,064 (215)

Efeito terapêutico do galato de etila na nocicepção neuropática e induzida por algógenos em camundongos [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2014.O galato de etila (GE) é um composto fenólico encontrado em um grande número de espécies de ...
Coelho, Igor dos Santos
core  

Targeted Overactivity of β Cell KATP Channels Induces Profound Neonatal Diabetes

, 2000
A paradigm for control of insulin secretion is that glucose metabolism elevates cytoplasmic [ATP]/[ADP] in β cells, closing KATP channels and causing depolarization, Ca2+ entry, and insulin release.
Koster, J.C, Ensor, N, Marshall, B.A, Corbett, J.A, Nichols, C.G   +4 more
core   +1 more source

KATP Channels and the Metabolic Regulation of Insulin Secretion in Health and Disease: The 2022 Banting Medal for Scientific Achievement Award Lecture. [PDF]

Diabetes, 2023
Ashcroft FM.
europepmc   +1 more source

Opening/blocking actions of pyruvate kinase antibodies on neuronal and muscular KATP channels

, 2012
ATP-sensitive-K+ (KATP) channels couple metabolism to the electrical activity of the cells. This channel is associated with glycolytic enzymes to form complexes regulating the channel activity in various tissues.
BUTTIGLIONE, Maura, Cannone G, TRICARICO, Domenico, Vitiello F, MELE, ANTONIETTA, CONTE, Diana   +5 more
core   +1 more source

[Retracted] Morphine‑induced delayed pre‑conditioning against anoxia/reoxygenation injury in pulmonary artery endothelial cells: The role of mitochondrial KATP channels. [PDF]

Mol Med Rep, 2023
Ding W, Guo Y, Cui X, Zhang B, Li D, Li W.   +5 more
europepmc   +1 more source

KATP channels in mouse spermatogenic cells and sperm, and their role in capacitation

, 2006
Mammalian sperm must undergo a series of physiological changes after leaving the testis to become competent for fertilization. These changes, collectively known as capacitation, occur in the female reproductive tract where the sperm plasma membrane is ...
Mendoza-Lujambio, Irene, Felix, Ricardo, Darszon, Alberto, Acevedo, Juan José, Treviño, Claudia L., de la Vega-Beltrán, José Luis   +5 more
core   +1 more source

Probing drug-binding to NBD1 of SUR2A, the regulatory subunit in cardiac KATP channels

, 2017
The sulfonylurea receptor 2A (SUR2A) forms the regulatory subunit in ATP-sensitive potassium (KATP) channels in the heart. KATP channels open upon MgATP binding and hydrolysis at the SUR2A nucleotide-binding domains (NBDs).
Park, Miriam Jungeun
core   +1 more source

Acute Metabolic Stress Induces Lymphatic Dysfunction Through KATP Channel Activation

Function
Lymphatic dysfunction is an underlying component of multiple metabolic diseases, including diabetes, obesity, and metabolic syndrome. We investigated the roles of KATP channels in lymphatic contractile dysfunction in response to acute metabolic stress ...
Hae Jin Kim, Charles E Norton, Scott D Zawieja, Jorge A Castorena-Gonzalez, Michael J Davis   +4 more
doaj   +1 more source

Closure by iptakalim, a cardiovascular KATP channel opener, of rat pancreatic β-cell KATP channels and its molecular basis [PDF]

application/pdfDiabetes mellitus is a group of diseases characterized by high levels of blood glucose resulting from defects in insulin production, insulin action, or both.
Wu, Jie, Wakui, Makoto, Misaki, Naoko, Suga, Sechiko, Lin, Yu-Fung, Mao, Xia   +5 more
core  

Cloning and functional expression of a rat heart KATP channel

, 1994
Potassium channels that are ATP-sensitive (KATP) couple membrane potential to the metabolic status of the cell. KATP channels are inhibited by intracellular ATP and are stimulated by intracellular nucleotide diphosphates.
Ashford, M. L. J.; id_orcid, M. L. J. Ashford, C. T. Bond, J. P. Adelmair, Bond, C. T., T. A. Blair, Blair, T. A., Adelman, J. P.   +7 more
core   +1 more source