Results 151 to 160 of about 811,037 (204)
Mechanisms Underlying the Biphasic Effects of Hydrogen Sulfide in Rat Intrapulmonary Arteries. [PDF]
Tunaitytė A +5 more
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Co-occurrence of Loss-of-Function GCK and ABCC8 Variants in a Pedigree With a Spectrum of Dysglycemia. [PDF]
Saint-Martin C +6 more
europepmc +1 more source
KATP Channels in the Cardiovascular System.
Foster MN, Coetzee WA.
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Postnatal refinement of Ca<sub>V</sub> channel isoform composition, electrical activity, and insulin release in mouse pancreatic β-cells. [PDF]
Theiner T +3 more
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Modulation of vascular KATP channels in hypothyroidism
European Journal of Pharmacology, 1996The role of vascular KATP channels in hypothyroidism-induced decrease in myogenic activity of rat portal vein was examined by using pharmacologically relevant concentrations of K+ channel ligands. As compared to controls, a significant decrease in the myogenic tone and noradrenaline (10(-9)-10(-5) M)-induced contractions was observed in portal veins ...
M, Jagadish +3 more
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KATP channels in vascular smooth muscle
Cardiovascular Research, 1994ATP sensitive potassium channels (KATP channels) appear widely distributed in the vascular system. At the single channel level, channels with both small and large conductance have been described, though the former appear to be activated by potassium channel openers or ATP depletion in whole cell studies.
J M, Quayle, N B, Standen
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KATP channel mutations in congenital hyperinsulinism
Seminars in Pediatric Surgery, 2011Adenosine triphosphate (ATP)-sensitive potassium channels (K(ATP) channels) have a central role in the regulation of insulin secretion in pancreatic β cells. They are octameric complexes organized around the central core constituted by the Kir6.2 subunits. The regulation of the channel itself takes place on the sulfonylurea receptor-1 subunit.
Cécile, Saint-Martin +3 more
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From congenital hyperinsulinism to diabetes mellitus: the role of pancreatic β-cell KATP channels
Pancreatic β-cell adenosine triphosphate (ATP)-sensitive potassium (KATP) channels play a pivotal role in linking glucose metabolism to regulated insulin secretion.
Khalid Hussain, Karen E Cosgrove
exaly +2 more sources
Brain glucosensing and the KATP channel
Nature Neuroscience, 2001An ATP-sensitive K+ channel in glucose-responsive neurons is shown to be required for the emergency response to severe glucose deprivation, but not necessarily for normal feeding.
Barry E. Levin +2 more
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Nature's KATP-Channel Knockout
Physiology, 1997We describe here how ion-channel dysfunction in b-cells is associated with the pathogenesis of a potentially lethal condition in newborn children and early infancy. We review how nature's KATP-channel knockout has important medical implications and how key lessons in physiology can be learned from studies of rare diseases.
MJ Dunne, A Aynsley-Green, KJ Lindley
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