HCV affects K<sub>ATP</sub> channels through GnT-IVa-mediated N-glycosylation of GLUT2 on the surface of pancreatic β-cells leading to impaired insulin secretion. [PDF]
Niu B, Ma L, Yao L, Zhang Y, Su H.
europepmc +1 more source
Stimulation of the calcium-sensing receptor induces relaxations of rat mesenteric arteries by endothelium-dependent and -independent pathways via BK<sub>Ca</sub> and K<sub>ATP</sub> channels. [PDF]
Carlton-Carew SRE +5 more
europepmc +1 more source
Co-occurrence of Loss-of-Function GCK and ABCC8 Variants in a Pedigree With a Spectrum of Dysglycemia. [PDF]
Saint-Martin C +6 more
europepmc +1 more source
Spent Coffee Ground Extracts: A Sustainable Source of Antioxidant and Immunomodulatory Bioactives for Managing Lifestyle-Related Chronic Diseases. [PDF]
Hasna A +10 more
europepmc +1 more source
KATP Channels in the Cardiovascular System.
Foster MN, Coetzee WA.
europepmc +1 more source
Related searches:
Modulation of vascular KATP channels in hypothyroidism
European Journal of Pharmacology, 1996The role of vascular KATP channels in hypothyroidism-induced decrease in myogenic activity of rat portal vein was examined by using pharmacologically relevant concentrations of K+ channel ligands. As compared to controls, a significant decrease in the myogenic tone and noradrenaline (10(-9)-10(-5) M)-induced contractions was observed in portal veins ...
M, Jagadish +3 more
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KATP channel mutations in congenital hyperinsulinism
Seminars in Pediatric Surgery, 2011Adenosine triphosphate (ATP)-sensitive potassium channels (K(ATP) channels) have a central role in the regulation of insulin secretion in pancreatic β cells. They are octameric complexes organized around the central core constituted by the Kir6.2 subunits. The regulation of the channel itself takes place on the sulfonylurea receptor-1 subunit.
Cécile, Saint-Martin +3 more
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KATP channels in vascular smooth muscle
Cardiovascular Research, 1994ATP sensitive potassium channels (KATP channels) appear widely distributed in the vascular system. At the single channel level, channels with both small and large conductance have been described, though the former appear to be activated by potassium channel openers or ATP depletion in whole cell studies.
J M, Quayle, N B, Standen
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