Results 181 to 190 of about 14,064 (215)

The KATP Channel and the Sulfonylurea Receptor

2001
ATP-sensitive K+ channels (KAgp channels) were first described in cardiac myocytes (1) and were subsequently found in many other tissues including pancreatic 13-cells (25), skeletal muscle (6), smooth muscle (7), brain (8), pituitary (9), and kidney (10) and in mitochondria (11).
Susumu Seino, Takashi Miki, Hideki Yano
openaire   +1 more source

Dihydropyridine KATP potassium channel openers

Bioorganic & Medicinal Chemistry Letters, 1993
Abstract Three related series of dihydropyridine K ATP potassium channel openers are described.
C.A. Frank, J.M. Forst, T. Grant, R.J. Harris, S.T. Kau, J.H. Li, C.J. Ohnmacht, R.W. Smith, D.A. Trainor, S. Trivedi   +9 more
openaire   +1 more source

KATP channels in ischaemic preconditioning

Cardiovascular Research, 1994
J R, Parratt, K A, Kane
openaire   +4 more sources

KATP channels as molecular sensors of cellular metabolism

Nature, 2006
In responding to cytoplasmic nucleotide levels, ATP-sensitive potassium (K(ATP)) channel activity provides a unique link between cellular energetics and electrical excitability. Over the past ten years, a steady drumbeat of crystallographic and electrophysiological studies has led to detailed structural and kinetic models that define the molecular ...
openaire   +2 more sources

KATP Channel-Independent Pathway and the Glucoreceptor

2018
The biphasic response is a unique characteristic of glucose-stimulated insulin secretion by islet beta cells. Namely, upon exposure to a high concentration of glucose, insulin secretion increases sharply for approximately 5 min before it gradually wanes at the end of the first phase.
Toru Aizawa, Mitsuhisa Komatsu
openaire   +1 more source

Cardiac KATP Channels in Health and Diseases

2013
Adenosine triphosphate (ATP)-sensitive K+ (KATP) channels were discovered in the heart almost 30 years ago. They are present in multiple tissues and link membrane excitability to the metabolic state of the cell. Under physiological conditions, cardiac KATP channels are predominantly closed, but they may open during exertion, stress, and ischemia ...
Hai Xia Zhang, Jonathan R. Silva, Colin G. Nichols   +2 more
openaire   +1 more source

KATP channel opening and cardioprotection

Cardiovascular Research, 1992
openaire   +3 more sources

KATP Channels

2006
openaire   +2 more sources

KATP Channels in the Pancreas

2016
M.S. Remedi, C.G. Nichols
openaire   +1 more source

KATP channels and migraine

2008
Inger Jansen-Olesen, Kenneth Beri Ploug
openaire   +1 more source