Results 121 to 130 of about 10,912 (234)

Variation in proteoglycan metabolism by articular chondrocytes in different joint regions is determined by post-natal mechanical loading [PDF]

, 1997
SummaryIn this study we investigated the hypothesis that cartilage from defined regions of ovine stifle joints, which were subjected to differing mechanical stresses, contained phenotypically distinct chondrocyte populations.
Ghosh, Peter, Little, Chris B.
core   +1 more source

Polymorphisms in Tunisian patients with N-acetylgalactosamine-6-sulfate sulfatase gene deficiency: Implication in Morquio A disease

Diagnostic Pathology, 2011
Mucopolysaccharidosis type IVA or Morquio A syndrome is characterized by the lack of N-acetylgalactosamine-6-sulfate-sulfatase and the accumulation of keratan sulfate and chondroitin-6-sulfate in the lysosomes.
Chkioua Latifa, Khedhiri Souhir, Ferchichi Salima, Miled Abdelhedi, Laradi Sandrine   +4 more
doaj   +1 more source

Iron oxide-coupled CRISPR-nCas9-based genome editing assessment in mucopolysaccharidosis IVA mice

Molecular Therapy: Methods & Clinical Development, 2023
Mucopolysaccharidosis (MPS) IVA is a lysosomal storage disorder caused by mutations in the GALNS gene that leads to the lysosomal accumulation of keratan sulfate (KS) and chondroitin 6-sulfate, causing skeletal dysplasia and cardiopulmonary complications.
Andrés Felipe Leal, Betul Celik, Nidhi Fnu, Shaukat Khan, Shunji Tomatsu, Carlos Javier Alméciga-Díaz   +5 more
doaj  

Structural Characterization and Anticoagulant Activities of a Keratan Sulfate-like Polysaccharide from the Sea Cucumber Holothuria fuscopunctata. [PDF]

Mar Drugs, 2023
Chen R, Wang W, Yin R, Pan Y, Xu C, Gao N, Luo X, Zhao J.   +7 more
europepmc   +1 more source

Effects of a synthetic bioactive peptide on neurite growth and nerve growth factor release in chondroitin sulfate hydrogels. [PDF]

, 2011
Previous work has revealed robust dorsal root ganglia neurite growth in hydrogels of chondroitin sulfate. In the current work, it was determined whether addition of a synthetic bioactive peptide could augment neurite growth in these matrices via enhanced
Beier, Brooke L, Conovaloff, Aaron W, Irazoqui, Pedro P, Panitch, Alyssa   +3 more
core   +1 more source

Bisphosphonate Treatment in a Patient Affected by MPS IVA with Osteoporotic Phenotype

Case Reports in Medicine, 2013
Morquio A syndrome (Mucopolysaccharidosis type IVA) (MPS IVA) is a rare inherited metabolic disorder characterized by the defective degradation of keratan sulfate and chondroitin-6-sulfate.
Albina Tummolo, Orazio Gabrielli, Alberto Gaeta, Maristella Masciopinto, Lucia Zampini, Luigi Michele Pavone, Paola Di Natale, Francesco Papadia   +7 more
doaj   +1 more source

Involvement of langerin in the protective function of a keratan sulfate-based disaccharide in an emphysema mouse model. [PDF]

J Biol Chem, 2023
Ohkawa Y, Kanto N, Nakano M, Fujinawa R, Kizuka Y, Johnson EL, Harada Y, Tamura JI, Taniguchi N.   +8 more
europepmc   +1 more source

Transport studies of chondroitin sulfate disaccharide through articular cartilage [PDF]

, 1997
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1997.Includes bibliographical references (leaves 56-57).by Julianne Jiang Zhu.M ...
Zhu, Julianne Jiang
core  

The relationship between keratan sulfate glycosaminoglycan density and mechanical stiffening of CXL treatment. [PDF]

Exp Eye Res, 2023
Hatami-Marbini H, Emu ME.
europepmc   +1 more source

Glycosaminoglycans: Sweet as Sugar Targets for Topical Skin Anti-Aging

Clinical, Cosmetic and Investigational Dermatology, 2021
Siew Tein Wang, Boon Hoe Neo, Richard J Betts L’Oréal Research & Innovation, L’Oréal Singapore, SingaporeCorrespondence: Richard J Betts Email richard.betts@rd.loreal.comAbstract: Glycosaminoglycans (GAGs) are long, linear polysaccharides comprised of ...
Wang ST, Neo BH, Betts RJ
doaj