Effects of a synthetic bioactive peptide on neurite growth and nerve growth factor release in chondroitin sulfate hydrogels. [PDF]
, 2011 Previous work has revealed robust dorsal root ganglia neurite growth in hydrogels of chondroitin sulfate. In the current work, it was determined whether addition of a synthetic bioactive peptide could augment neurite growth in these matrices via enhanced
Beier, Brooke L +3 more
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How Growth Cones Sense Extracellular Cues and Drive Neuronal Migration
BioEssays, Volume 47, Issue 10, October 2025.Migrating neurons and growing axons utilize structurally and functionally similar growth cones to detect guidance cues. Shared receptors and signaling pathways mediate cytoskeletal reorganization to direct movement. This conserved mechanism underlies both neuronal migration and axon extension, providing insights into neuronal development and potential ...
Takahiro Kanzawa +3 more
wiley +1 more source
Transport studies of chondroitin sulfate disaccharide through articular cartilage [PDF]
, 1997 Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1997.Includes bibliographical references (leaves 56-57).by Julianne Jiang Zhu.M ...
Zhu, Julianne Jiang
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Application of Chondroitin Sulfate Derivatives for Understanding Axonal Guidance in the Nervous System during Development [PDF]
, 2013 Neuronal axons and their growth cones recognize molecular guidance cues within the local environment, forming axonal pathways to produce precise neuronal networks during nervous system development.
Ichijo Hiroyuki +2 more
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The Sweet Aspects of Orthoflavivirus Treatment Design and Vaccine Development
Journal of Medical Virology, Volume 97, Issue 10, October 2025.ABSTRACT Viruses in the genus Orthoflavivirus are among the most important human pathogens because of their significant public health impact. Many strategies have been proposed to develop specific or broad‐spectrum treatments and preventive measures for these viral infections in humans.
Ana C. Alcalá +2 more
wiley +1 more source
Arthritis Research & Therapy, 2017 Background We aimed to determine whether synovial fluid (SF) biomarkers can predict the progression of articular cartilage damage as determined by arthroscopic evaluation during and after anterior cruciate ligament (ACL) reconstruction.
Yasumori Sobue +6 more
doaj +1 more source
Contaminants in commercial preparations of ‘purified’ small leucine-rich proteoglycans may distort mechanistic studies [PDF]
, 2017 The authors are grateful to Genodisc (EC’s 7th Framework Programme (FP7, 2007-2013) under grant agreement no. HEALTH-F2-2008-201626) and the Orthopaedic Institute Ltd for funding.This paper reports the perplexing results that came about because of ...
Botting, Catherine H. +6 more
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A systemic review of existing serological possibilities to diagnose canine osteoarthritis with a particular focus on extracellular matrix proteoglycans and protein [PDF]
, 2017 Extra-cellular matrix (ECM) components are important and their stabilization is significant in maintaining normal healthy joint environment. In osteoarthritis (OA), ECM components are altered and indicate disease progression. The joint ECM is composed
Fatima, A. +6 more
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Identification of a carbohydrate-based endothelial ligand for a lymphocyte homing receptor. [PDF]
, 1991 Lymphocyte attachment to high endothelial venules within lymph nodes is mediated by the peripheral lymph node homing receptor (pnHR), originally defined on mouse lymphocytes by the MEL-14 mAb.
Fennie, C +4 more
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Elucidating glycosaminoglycan–protein–protein interactions using carbohydrate microarray and computational approaches [PDF]
, 2011 Glycosaminoglycan polysaccharides play critical roles in many cellular processes, ranging from viral invasion and angiogenesis to spinal cord injury.
Bothwell +39 more
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