Differentiation of Human Embryonic Stem Cells into Cells with Corneal Keratocyte Phenotype [PDF]
, 2013 Corneal transparency depends on a unique extracellular matrix secreted by stromal keratocytes, mesenchymal cells of neural crest lineage. Derivation of keratocytes from human embryonic stem (hES) cells could elucidate the keratocyte developmental pathway
Chan, AA +8 more
core +9 more sources
Biomolecules, 2021 We developed two human-induced pluripotent stem cell (hiPSC)/human embryonic stem cell (hESC)-specific glycan-recognizing mouse antibodies, R-10G and R-17F, using the Tic (JCRB1331) hiPSC line as an antigen. R-10G recognizes a low-sulfate keratan sulfate,
Yuko Nagai +8 more
doaj +1 more source
Dietary Keratan Sulfate from Shark Cartilage Modulates Gut Microbiota and Increases the Abundance of Lactobacillus spp. [PDF]
Mar Drugs, 2016 Shang Q +9 more
europepmc +3 more sources
Human Corneal Keratan Sulfates [PDF]
Journal of Biological Chemistry, 1997 The keratan sulfate-containing proteoglycans were isolated from fourteen pooled human corneas (thirteen from 61- to 86-year-olds, plus one from a 12-year-old). These proteoglycans were subjected to digestion with the enzyme keratanase II, and the released oligosaccharides, which included nonreducing termini and repeat region oligosaccharides but not ...
Tai, G H +3 more
openaire +2 more sources
Immunolocalization of Keratan Sulfate Proteoglycan in Rat Calvaria.
Archives of Histology and Cytology, 2001 We investigate, by the immunogold method, the localization of keratan sulfate (KS) proteoglycan in rat calvaria in order to clarify the detailed process of intramembranous ossification. KS was localized in bone nodules corresponding to calcified nodules, close to the saggital suture of calvaria. The immunoreactivity decreased in fully calcified regions
Hiroaki Nakamura +3 more
openalex +5 more sources
KSGal6ST is essential for the 6-sulfation of galactose within keratan sulfate in early postnatal brain. [PDF]
J Histochem Cytochem, 2014 Hoshino H +6 more
europepmc +2 more sources
Urinary keratan sulfate of Morquio's disease.
The Tohoku Journal of Experimental Medicine, 1980 To elucidate precise chemical nature of urinary keratan sulfate (KS) of Morquio's disease, crude glycosaminoglycans (GAG) were separated from 24-hr urines of 3 patients with Morquio's disease and from pooled urine of a healthy boy, using cetylpyridinium chloride.
Osamu Namiki +4 more
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An improved method for the structural profiling of keratan sulfates: analysis of keratan sulfates from brain and ovarian tumors [PDF]
Glycobiology, 1999 A previously developed method for the structural fingerprinting of keratan sulfates (Brown et al., Glycobiology, 5, 311-317, 1995) has been adapted for use with oligosaccharides fluorescently labeled with 2-aminobenzoic acid following keratanase II digestion.
Karen Whitham +5 more
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Larynx proteomics after jellyfish collagen IL: Increased ECM/collagen and suppressed inflammation
Laryngoscope Investigative Otolaryngology, 2022 Objectives/Hypothesis Compare proteomic profiles of rabbit vocal folds (VFs) injected with micronized cross‐linked jellyfish collagen “collagen Type 0” (MX‐JC) against two clinical products for injection medialization laryngoplasty (IL).
Andrew J. Bowen +7 more
doaj +1 more source
Mucopolysaccharidosis IVA: Diagnosis, Treatment, and Management. [PDF]
, 2020 Mucopolysaccharidosis type IVA (MPS IVA, or Morquio syndrome type A) is an inherited metabolic lysosomal disease caused by the deficiency of the N-acetylglucosamine-6-sulfate sulfatase enzyme.
Couce, Maria L. +6 more
core +2 more sources